Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation F Modarresi, MA Faghihi, MA Lopez-Toledano, RP Fatemi, M Magistri, ... Nature biotechnology 30 (5), 453-459, 2012 | 675 | 2012 |
Emerging treatment strategies for glioblastoma multiforme SK Carlsson, SP Brothers, C Wahlestedt EMBO molecular medicine 6 (11), 1359-1370, 2014 | 398 | 2014 |
Pharmacologic rescue of conformationally‐defective proteins: implications for the treatment of human disease A Ulloa‐Aguirre, JA Janovick, SP Brothers, PM Conn Traffic 5 (11), 821-837, 2004 | 294 | 2004 |
Therapeutic potential of neuropeptide Y (NPY) receptor ligands SP Brothers, C Wahlestedt EMBO molecular medicine 2 (11), 429-439, 2010 | 288 | 2010 |
A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome AM Khalil, MA Faghihi, F Modarresi, SP Brothers, C Wahlestedt PLoS One 3 (1), e1486, 2008 | 198 | 2008 |
Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model KJ Janczura, CH Volmar, GC Sartor, SJ Rao, NR Ricciardi, G Lambert, ... Proceedings of the National Academy of Sciences 115 (47), E11148-E11157, 2018 | 165 | 2018 |
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD R Andero, SP Brothers, T Jovanovic, YT Chen, H Salah-Uddin, ... Science translational medicine 5 (188), 188ra73-188ra73, 2013 | 161 | 2013 |
BET bromodomain proteins are required for glioblastoma cell proliferation C Pastori, M Daniel, C Penas, CH Volmar, AL Johnstone, SP Brothers, ... Epigenetics 9 (4), 611-620, 2014 | 155 | 2014 |
Addition of catfish gonadotropin-releasing hormone (GnRH) receptor intracellular carboxyl-terminal tail to rat GnRH receptor alters receptor expression and regulation X Lin, JA Janovick, S Brothers, M Blömenrohr, J Bogerd, PM Conn Molecular Endocrinology 12 (2), 161-171, 1998 | 143 | 1998 |
Regulation of Gq/11α by the Gonadotropin-Releasing Hormone Receptor D Stanislaus, JA Janovick, S Brothers, PM Conn Molecular Endocrinology 11 (6), 738-746, 1997 | 125 | 1997 |
Oxytocin and social functioning C Jones, I Barrera, S Brothers, R Ring, C Wahlestedt Dialogues in clinical neuroscience 19 (2), 193-201, 2017 | 114 | 2017 |
Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: molecular basis of the dominant-negative effect SP Brothers, A Cornea, JA Janovick, PM Conn Molecular Endocrinology 18 (7), 1787-1797, 2004 | 100 | 2004 |
Systemic reprogramming of translation efficiencies on oxygen stimulus JJD Ho, M Wang, TE Audas, D Kwon, SK Carlsson, S Timpano, ... Cell reports 14 (6), 1293-1300, 2016 | 99 | 2016 |
mRNA-to-protein translation in hypoxia NT Chee, I Lohse, SP Brothers Molecular cancer 18 (1), 49, 2019 | 90 | 2019 |
Epigenetic readers of lysine acetylation regulate cocaine-induced plasticity GC Sartor, SK Powell, SP Brothers, C Wahlestedt Journal of Neuroscience 35 (45), 15062-15072, 2015 | 76 | 2015 |
Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening SP Brothers, SA Saldanha, TP Spicer, M Cameron, BA Mercer, P Chase, ... Molecular pharmacology 77 (1), 46-57, 2010 | 76 | 2010 |
Regulation of G protein-coupled receptor trafficking by inefficient plasma membrane expression: molecular basis of an evolved strategy JA Janovick, PE Knollman, SP Brothers, R Ayala-Yáñez, AS Aziz, ... Journal of Biological Chemistry 281 (13), 8417-8425, 2006 | 76 | 2006 |
Unexpected effects of epitope and chimeric tags on gonadotropin-releasing hormone receptors: implications for understanding the molecular etiology of hypogonadotropic hypogonadism SP Brothers, JA Janovick, PM Conn The Journal of Clinical Endocrinology & Metabolism 88 (12), 6107-6112, 2003 | 64 | 2003 |
Pathogenesis and treatment of pancreatic cancer related pain I Lohse, SP Brothers Anticancer research 40 (4), 1789-1796, 2020 | 61 | 2020 |
Protein folding as posttranslational regulation: evolution of a mechanism for controlled plasma membrane expression of a G protein-coupled receptor PM Conn, PE Knollman, SP Brothers, JA Janovick Molecular endocrinology 20 (12), 3035-3041, 2006 | 61 | 2006 |