PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans IL Berg, R Neumann, KWG Lam, S Sarbajna, L Odenthal-Hesse, CA May, ... Nature genetics 42 (10), 859-863, 2010 | 376 | 2010 |
Noninvasive prenatal diagnosis of monogenic diseases by targeted massively parallel sequencing of maternal plasma: application to â-thalassemia KWG Lam, P Jiang, GJW Liao, KCA Chan, TY Leung, RWK Chiu, YMD Lo Clinical chemistry 58 (10), 1467-1475, 2012 | 222 | 2012 |
Quantitative RT-PCR methods for evaluating toxicant-induced effects on steroidogenesis using the H295R cell line JP Zhang, X., Yu, R. M. K., Jones, P. D., Lam, G. K. W., Newsted, J. L ... Environ Sci Technol 39, 2777-2785, 2005 | 129 | 2005 |
High-throughput single-cell sequencing with linear amplification Y Yin, Y Jiang, KWG Lam, JB Berletch, CM Disteche, WS Noble, ... Molecular cell 76 (4), 676-690. e10, 2019 | 95 | 2019 |
Processes of copy-number change in human DNA: the dynamics of á-globin gene deletion KWG Lam, AJ Jeffreys Proceedings of the National Academy of Sciences 103 (24), 8921-8927, 2006 | 90 | 2006 |
Extensive sex differences at the initiation of genetic recombination K Brick, S Thibault-Sennett, F Smagulova, KWG Lam, Y Pu, F Pratto, ... Nature 561 (7723), 338-342, 2018 | 79 | 2018 |
Processes of de novo duplication of human á-globin genes KWG Lam, AJ Jeffreys Proceedings of the National Academy of Sciences 104 (26), 10950-10955, 2007 | 73 | 2007 |
Recombination regulator PRDM9 influences the instability of its own coding sequence in humans AJ Jeffreys, VE Cotton, R Neumann, KWG Lam Proceedings of the National Academy of Sciences 110 (2), 600-605, 2013 | 54 | 2013 |
Meiotic recombination mirrors patterns of germline replication in mice and humans F Pratto, K Brick, G Cheng, KWG Lam, JM Cloutier, D Dahiya, SR Wellard, ... Cell 184 (16), 4251-4267. e20, 2021 | 38 | 2021 |
Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis KWG Lam, K Brick, G Cheng, F Pratto, RD Camerini-Otero Nature Communications 10 (1), 3821, 2019 | 32 | 2019 |
A BDNF-TrkB autocrine loop enhances senescent cell viability C Anerillas, AB Herman, R Munk, A Garrido, KWG Lam, MJ Payea, ... Nature communications 13 (1), 6228, 2022 | 14 | 2022 |
The YAP–TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress C Anerillas, K Mazan-Mamczarz, AB Herman, R Munk, KWG Lam, ... Nature Aging 3 (10), 1237-1250, 2023 | 6 | 2023 |
Germline DNA replication shapes the recombination landscape in mammals F Pratto, K Brick, G Cheng, G Lam, JM Cloutier, D Dahiya, SR Wellard, ... bioRxiv, 2020.09. 23.308874, 2020 | 2 | 2020 |
Increased PTCHD4 expression via m6A modification of PTCHD4 mRNA promotes senescent cell survival M Rossi, N Banskota, CH Shin, C Anerillas, D Tsitsipatis, JH Yang, ... Nucleic Acids Research, gkae322, 2024 | | 2024 |
High resolution maps of chromatin reorganization through mouse meiosis reveal novel features of the 3D meiotic structure G Cheng, F Pratto, K Brick, X Li, B Alleva, M Huang, G Lam, ... bioRxiv, 2024.03. 25.586627, 2024 | | 2024 |
DNA instability in the human alpha-globin gene cluster KWG Lam PQDT-UK & Ireland, 2007 | | 2007 |