Bertus Eksteen
Bertus Eksteen
Associate Professor of Medicine, University of Calgary
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Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells
JR Mora, M Iwata, B Eksteen, SY Song, T Junt, B Senman, KL Otipoby, ...
Science 314 (5802), 1157-1160, 2006
Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans
E Jaensson, H Uronen-Hansson, O Pabst, B Eksteen, J Tian, JL Coombes, ...
The Journal of experimental medicine 205 (9), 2139-2149, 2008
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
JZ Liu, JR Hov, T Folseraas, E Ellinghaus, SM Rushbrook, NT Doncheva, ...
Nature genetics 45 (6), 670-675, 2013
Hepatic endothelial CCL25 mediates the recruitment of CCR9+ gut-homing lymphocytes to the liver in primary sclerosing cholangitis
B Eksteen, AJ Grant, A Miles, SM Curbishley, PF Lalor, SG Hübscher, ...
The Journal of experimental medicine 200 (11), 1511-1517, 2004
Aberrant homing of mucosal T cells and extra-intestinal manifestations of inflammatory bowel disease
DH Adams, B Eksteen
Nature Reviews Immunology 6 (3), 244-251, 2006
Patient age, sex, and inflammatory bowel disease phenotype associate with course of primary sclerosing cholangitis
TJ Weismüller, PJ Trivedi, A Bergquist, M Imam, H Lenzen, CY Ponsioen, ...
Gastroenterology 152 (8), 1975-1984. e8, 2017
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver
YH Oo, CJ Weston, PF Lalor, SM Curbishley, DR Withers, GM Reynolds, ...
The Journal of Immunology 184 (6), 2886-2898, 2010
Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10
B Eksteen, A Miles, SM Curbishley, C Tselepis, AJ Grant, LSK Walker, ...
The Journal of Immunology 177 (1), 593-603, 2006
CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver
YH Oo, V Banz, D Kavanagh, E Liaskou, DR Withers, E Humphreys, ...
Journal of hepatology 57 (5), 1044-1051, 2012
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
SG Ji, BD Juran, S Mucha, T Folseraas, L Jostins, E Melum, N Kumasaka, ...
Nature genetics 49 (2), 269-273, 2017
CXCR3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow
SM Curbishley, B Eksteen, RP Gladue, P Lalor, DH Adams
The American journal of pathology 167 (3), 887-899, 2005
Impact of obesity on remission and disease activity in rheumatoid arthritis: a systematic review and meta‐analysis
Y Liu, GS Hazlewood, GG Kaplan, B Eksteen, C Barnabe
Arthritis care & research 69 (2), 157-165, 2017
Gut homing receptors on CD8 T cells are retinoic acid dependent and not maintained by liver dendritic or stellate cells
B Eksteen, JR Mora, EL Haughton, NC Henderson, L Lee–Turner, ...
Gastroenterology 137 (1), 320-329, 2009
Characterization of animal models for primary sclerosing cholangitis (PSC)
P Fickert, MJ Pollheimer, U Beuers, C Lackner, G Hirschfield, C Housset, ...
Journal of hepatology 60 (6), 1290-1303, 2014
Lymphocyte homing and its role in the pathogenesis of IBD
B Eksteen, E Liaskou, DH Adams
Inflammatory bowel diseases 14 (9), 1298-1312, 2008
Kupffer cells undergo fundamental changes during the development of experimental NASH and are critical in initiating liver damage and inflammation
DT Reid, JL Reyes, BA McDonald, T Vo, RA Reimer, B Eksteen
PloS one 11 (7), e0159524, 2016
Postoperative mortality among patients with inflammatory bowel diseases: a systematic review and meta-analysis of population-based studies
S Singh, A Al-Darmaki, AD Frolkis, CH Seow, Y Leung, KL Novak, ...
Gastroenterology 149 (4), 928-937, 2015
Immunology of the gut and liver: a love/hate relationship
DH Adams, B Eksteen, SM Curbishley
Gut 57 (6), 838-848, 2008
Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice
JD Coombes, M Swiderska-Syn, L Dollé, D Reid, B Eksteen, L Claridge, ...
Gut 64 (7), 1120-1131, 2015
The nonsteroidal farnesoid X receptor agonist cilofexor (GS‐9674) improves markers of cholestasis and liver injury in patients with primary sclerosing cholangitis
M Trauner, A Gulamhusein, B Hameed, S Caldwell, ML Shiffman, ...
Hepatology 70 (3), 788-801, 2019
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