| Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints DA Skoufias, PR Andreassen, FB Lacroix, L Wilson, RL Margolis Proceedings of the National Academy of Sciences 98 (8), 4492-4497, 2001 | 376 | 2001 |
| Crystal structure of human survivin reveals a bow tie–shaped dimer with two unusual α-helical extensions L Chantalat, DA Skoufias, JP Kleman, B Jung, O Dideberg, RL Margolis Molecular cell 6 (1), 183-189, 2000 | 359 | 2000 |
| Human survivin is a kinetochore-associated passenger protein DA Skoufias, C Mollinari, FB Lacroix, RL Margolis The Journal of cell biology 151 (7), 1575-1582, 2000 | 355 | 2000 |
| S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression DA Skoufias, S DeBonis, Y Saoudi, L Lebeau, I Crevel, R Cross, ... Journal of biological chemistry 281 (26), 17559-17569, 2006 | 302 | 2006 |
| Structure and dynamics of a 197 bp nucleosome in complex with linker histone H1 J Bednar, I Garcia-Saez, R Boopathi, AR Cutter, G Papai, A Reymer, ... Molecular cell 66 (3), 384-397. e8, 2017 | 288 | 2017 |
| In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities S Debonis, DA Skoufias, L Lebeau, R Lopez, G Robin, RL Margolis, ... Molecular cancer therapeutics 3 (9), 1079-1090, 2004 | 274 | 2004 |
| Interaction of the mitotic inhibitor monastrol with human kinesin Eg5 S DeBonis, JP Simorre, I Crevel, L Lebeau, DA Skoufias, A Blangy, ... Biochemistry 42 (2), 338-349, 2003 | 239 | 2003 |
| Mechanism of inhibition of microtubule polymerization by colchicine: inhibitory potencies of unliganded colchicine and tubulin-colchicine complexes DA Skoufias, L Wilson Biochemistry 31 (3), 738-746, 1992 | 187 | 1992 |
| New chemical tools for investigating human mitotic kinesin Eg5 E Klein, S DeBonis, B Thiede, DA Skoufias, F Kozielski, L Lebeau Bioorganic & medicinal chemistry 15 (19), 6474-6488, 2007 | 180 | 2007 |
| Isolation of a sea urchin egg kinesin-related protein using peptide antibodies DG Cole, WZ Cande, RJ Baskin, DA Skoufias, CJ Hogan, JM Scholey Journal of cell science 101 (2), 291-301, 1992 | 143 | 1992 |
| The carboxyl-terminal domain of kinesin heavy chain is important for membrane binding. DA Skoufias, DG Cole, KP Wedaman, JM Scholey Journal of Biological Chemistry 269 (2), 1477-1485, 1994 | 141 | 1994 |
| Inhibition of DNA decatenation, but not DNA damage, arrests cells at metaphase DA Skoufias, FB Lacroix, PR Andreassen, L Wilson, RL Margolis Molecular cell 15 (6), 977-990, 2004 | 130 | 2004 |
| Cytoplasmic microtubule-based motor proteins DA Skoufias, JM Scholey Current opinion in cell biology 5 (1), 95-104, 1993 | 130 | 1993 |
| Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressed DA Skoufias, RL Indorato, F Lacroix, A Panopoulos, RL Margolis The Journal of cell biology 179 (4), 671-685, 2007 | 125 | 2007 |
| Structure of an H1-bound 6-nucleosome array reveals an untwisted two-start chromatin fiber conformation I Garcia-Saez, H Menoni, R Boopathi, MS Shukla, L Soueidan, ... Molecular cell 72 (5), 902-915. e7, 2018 | 102 | 2018 |
| The flexible ends of CENP-A nucleosome are required for mitotic fidelity Y Roulland, K Ouararhni, M Naidenov, L Ramos, M Shuaib, SH Syed, ... Molecular cell 63 (4), 674-685, 2016 | 98 | 2016 |
| Structural Basis of Cytotoxicity Mediated by the Type III Secretion Toxin ExoU from Pseudomonas aeruginosa C Gendrin, C Contreras-Martel, S Bouillot, S Elsen, D Lemaire, ... PLoS pathogens 8 (4), e1002637, 2012 | 96 | 2012 |
| Structure–Activity Relationship of S-Trityl-l-Cysteine Analogues as Inhibitors of the Human Mitotic Kinesin Eg5 S DeBonis, DA Skoufias, RL Indorato, F Liger, B Marquet, C Laggner, ... Journal of medicinal chemistry 51 (5), 1115-1125, 2008 | 80 | 2008 |
| Molecular distinctions between Aurora A and B: a single residue change transforms Aurora A into correctly localized and functional Aurora B F Hans, DA Skoufias, S Dimitrov, RL Margolis Molecular biology of the cell 20 (15), 3491-3502, 2009 | 79 | 2009 |
| Eg5 targeting agents: From new anti-mitotic based inhibitor discovery to cancer therapy and resistance I Garcia-Saez, DA Skoufias Biochemical Pharmacology 184, 114364, 2021 | 73 | 2021 |
