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Guangxin Li
Guangxin Li
Verified email at yale.edu
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Cited by
Year
Endothelial-to-mesenchymal transition drives atherosclerosis progression
PY Chen, L Qin, N Baeyens, G Li, T Afolabi, M Budatha, G Tellides, ...
The Journal of clinical investigation 125 (12), 4514-4528, 2015
4852015
Endothelial TGF-â signalling drives vascular inflammation and atherosclerosis
PY Chen, L Qin, G Li, Z Wang, JE Dahlman, J Malagon-Lopez, S Gujja, ...
Nature metabolism 1 (9), 912-926, 2019
2042019
Smooth muscle cell reprogramming in aortic aneurysms
PY Chen, L Qin, G Li, J Malagon-Lopez, Z Wang, S Bergaya, S Gujja, ...
Cell stem cell 26 (4), 542-557. e11, 2020
1422020
Caveolin-1 regulates atherogenesis by attenuating low-density lipoprotein transcytosis and vascular inflammation independently of endothelial nitric oxide synthase activation
CM Ramírez, X Zhang, C Bandyopadhyay, N Rotllan, MG Sugiyama, ...
Circulation 140 (3), 225-239, 2019
1202019
Tissue-engineered vascular grafts with advanced mechanical strength from human iPSCs
J Luo, L Qin, L Zhao, L Gui, MW Ellis, Y Huang, MH Kural, JA Clark, S Ono, ...
Cell Stem Cell 26 (2), 251-261. e8, 2020
1102020
Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells
J Cui, L Qin, J Zhang, P Abrahimi, H Li, G Li, GT Tietjen, G Tellides, ...
Nature Communications 8 (1), 191, 2017
892017
Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGFâ)-dependent smooth muscle cell phenotype modulation
PY Chen, L Qin, G Li, G Tellides, M Simons
Scientific reports 6 (1), 33407, 2016
822016
Smooth muscle FGF/TGF â cross talk regulates atherosclerosis progression
PY Chen, L Qin, G Li, G Tellides, M Simons
EMBO molecular medicine 8 (7), 712-728, 2016
822016
Pharmacologically improved contractility protects against aortic dissection in mice with disrupted transforming growth factor-â signaling despite compromised extracellular …
J Ferruzzi, SI Murtada, G Li, Y Jiao, S Uman, MYL Ting, G Tellides, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (5), 919-927, 2016
752016
Chronic mTOR activation induces a degradative smooth muscle cell phenotype
G Li, M Wang, AW Caulk, NA Cilfone, S Gujja, L Qin, PY Chen, Z Chen, ...
The Journal of clinical investigation 130 (3), 1233-1251, 2020
722020
Complement membrane attack complexes activate noncanonical NF-êB by forming an Akt+ NIK+ signalosome on Rab5+ endosomes
D Jane-wit, YV Surovtseva, L Qin, G Li, R Liu, P Clark, TD Manes, C Wang, ...
Proceedings of the National Academy of Sciences 112 (31), 9686-9691, 2015
682015
Complement membrane attack complexes assemble NLRP3 inflammasomes triggering IL-1 activation of IFN-ã–primed human endothelium
CB Xie, L Qin, G Li, C Fang, NC Kirkiles-Smith, G Tellides, JS Pober, ...
Circulation research 124 (12), 1747-1759, 2019
622019
Improving in vivo outcomes of decellularized vascular grafts via incorporation of a novel extracellular matrix
NJ Kristofik, L Qin, NE Calabro, S Dimitrievska, G Li, G Tellides, ...
Biomaterials 141, 63-73, 2017
592017
Deficient circumferential growth is the primary determinant of aortic obstruction attributable to partial elastin deficiency
Y Jiao, G Li, A Korneva, AW Caulk, L Qin, MR Bersi, Q Li, W Li, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (5), 930-941, 2017
522017
Inhibition of the mTOR pathway in abdominal aortic aneurysm: implications of smooth muscle cell contractile phenotype, inflammation, and aneurysm expansion
G Li, L Qin, L Wang, X Li, AW Caulk, J Zhang, PY Chen, S Xin
American Journal of Physiology-Heart and Circulatory Physiology 312 (6 …, 2017
442017
Vascular smooth muscle cells derived from inbred swine induced pluripotent stem cells for vascular tissue engineering
J Luo, L Qin, MH Kural, J Schwan, X Li, O Bartulos, X Cong, Y Ren, L Gui, ...
Biomaterials 147, 116-132, 2017
402017
Glycocalyx‐Like Hydrogel Coatings for Small Diameter Vascular Grafts
S Dimitrievska, J Wang, T Lin, A Weyers, H Bai, L Qin, G Li, C Cai, ...
Advanced Functional Materials 30 (23), 1908963, 2020
392020
Endothelial cell–derived interleukin-18 released during ischemia reperfusion injury selectively expands t peripheral helper cells to promote alloantibody production
L Liu, C Fang, W Fu, B Jiang, G Li, L Qin, J Rosenbluth, G Gong, CB Xie, ...
Circulation 141 (6), 464-478, 2020
342020
ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-êB via phosphoinosotide remodeling of endosomes
C Fang, TD Manes, L Liu, K Liu, L Qin, G Li, Z Tobiasova, ...
Nature communications 10 (1), 2247, 2019
322019
mTOR (mechanistic target of rapamycin) inhibition decreases mechanosignaling, collagen accumulation, and stiffening of the thoracic aorta in elastin-deficient mice
Y Jiao, G Li, Q Li, R Ali, L Qin, W Li, Y Qyang, DM Greif, A Geirsson, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 37 (9), 1657-1666, 2017
312017
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