Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome RW Tothill, AV Tinker, J George, R Brown, SB Fox, S Lade, DS Johnson, ... Clinical cancer research 14 (16), 5198-5208, 2008 | 1526 | 2008 |
Whole–genome characterization of chemoresistant ovarian cancer AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ... Nature 521 (7553), 489-494, 2015 | 1475 | 2015 |
Next-generation sequencing for cancer diagnostics: a practical perspective C Meldrum, MA Doyle, RW Tothill The Clinical Biochemist Reviews 32 (4), 177, 2011 | 580 | 2011 |
Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis S Moran, A Martínez-Cardús, S Sayols, E Musulén, C Balañá, ... The Lancet Oncology 17 (10), 1386-1395, 2016 | 434 | 2016 |
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer ML Burr, CE Sparbier, KL Chan, YC Chan, A Kersbergen, EYN Lam, ... Cancer cell 36 (4), 385-401. e8, 2019 | 415 | 2019 |
Options available—from start to finish—for obtaining data from DNA microarrays II AJ Holloway, RK Van Laar, RW Tothill, DDL Bowtell Nature genetics 32 (4), 481-489, 2002 | 386 | 2002 |
CONTRA: copy number analysis for targeted resequencing J Li, R Lupat, KC Amarasinghe, ER Thompson, MA Doyle, GL Ryland, ... Bioinformatics 28 (10), 1307-1313, 2012 | 372 | 2012 |
UV-associated mutations underlie the etiology of MCV-negative Merkel cell carcinomas SQ Wong, K Waldeck, IA Vergara, J Schröder, J Madore, JS Wilmott, ... Cancer research 75 (24), 5228-5234, 2015 | 328 | 2015 |
Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas D Etemadmoghadam, A Defazio, R Beroukhim, C Mermel, J George, ... Clinical cancer research 15 (4), 1417-1427, 2009 | 326 | 2009 |
An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin RW Tothill, A Kowalczyk, D Rischin, A Bousioutas, I Haviv, RK van Laar, ... Cancer Research 65 (10), 4031-4040, 2005 | 261 | 2005 |
Exome Sequencing Identifies Rare Deleterious Mutations in DNA Repair Genes FANCC and BLM as Potential Breast Cancer Susceptibility Alleles ER Thompson, MA Doyle, GL Ryland, SM Rowley, DYH Choong, ... Public Library of Science 8 (9), e1002894, 2012 | 254 | 2012 |
Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells L Pirola, A Balcerczyk, RW Tothill, I Haviv, A Kaspi, S Lunke, M Ziemann, ... Genome research 21 (10), 1601-1615, 2011 | 241 | 2011 |
68Ga-DOTATATE and 18F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneity CA Chang, DA Pattison, RW Tothill, G Kong, TJ Akhurst, RJ Hicks, ... Cancer Imaging 16, 1-12, 2016 | 169 | 2016 |
Loss of heterozygosity: what is it good for? GL Ryland, MA Doyle, D Goode, SE Boyle, DYH Choong, SM Rowley, J Li, ... BMC medical genomics 8, 1-12, 2015 | 160 | 2015 |
BRAF/NRAS Wild-Type Melanomas Have a High Mutation Load Correlating with Histologic and Molecular Signatures of UV Damage VJ Mar, SQ Wong, J Li, RA Scolyer, C McLean, AT Papenfuss, RW Tothill, ... Clinical Cancer Research 19 (17), 4589-4598, 2013 | 153 | 2013 |
Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors MS Anglesio, JM Arnold, J George, AV Tinker, R Tothill, N Waddell, ... Molecular cancer research 6 (11), 1678-1690, 2008 | 148 | 2008 |
Massively‐parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary RW Tothill, J Li, L Mileshkin, K Doig, T Siganakis, P Cowin, A Fellowes, ... The Journal of pathology 231 (4), 413-423, 2013 | 120 | 2013 |
Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC JC Becker, A Stang, A Hausen, N Fischer, JA DeCaprio, RW Tothill, ... Cancer Immunology, Immunotherapy 67 (3), 341-351, 2018 | 111 | 2018 |
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1 J Le Nours, NA Gherardin, SH Ramarathinam, W Awad, F Wiede, ... Science 366 (6472), 1522-1527, 2019 | 105 | 2019 |
Socrates: identification of genomic rearrangements in tumour genomes by re-aligning soft clipped reads J Schröder, A Hsu, SE Boyle, G Macintyre, M Cmero, RW Tothill, ... Bioinformatics 30 (8), 1064-1072, 2014 | 100 | 2014 |