A 45-amino-acid scaffold mined from the PDB for high-affinity ligand engineering MA Kruziki, S Bhatnagar, DR Woldring, VT Duong, BJ Hackel Chemistry & biology 22 (7), 946-956, 2015 | 69 | 2015 |
High-throughput ligand discovery reveals a sitewise gradient of diversity in broadly evolved hydrophilic fibronectin domains DR Woldring, PV Holec, H Zhou, BJ Hackel PLoS One 10 (9), e0138956, 2015 | 48 | 2015 |
A gradient of sitewise diversity promotes evolutionary fitness for binder discovery in a three-helix bundle protein scaffold DR Woldring, PV Holec, LA Stern, Y Du, BJ Hackel Biochemistry 56 (11), 1656-1671, 2017 | 40 | 2017 |
Titratable avidity reduction enhances affinity discrimination in mammalian cellular selections of yeast-displayed ligands LA Stern, CM Csizmar, DR Woldring, CR Wagner, BJ Hackel ACS combinatorial science 19 (5), 315-323, 2017 | 34 | 2017 |
64Cu-Labeled Gp2 Domain for PET Imaging of Epidermal Growth Factor Receptor MA Kruziki, BA Case, JY Chan, EJ Zudock, DR Woldring, D Yee, ... Molecular pharmaceutics 13 (11), 3747-3755, 2016 | 21 | 2016 |
ScaffoldSeq: Software for characterization of directed evolution populations DR Woldring, PV Holec, BJ Hackel Proteins: Structure, Function, and Bioinformatics 84 (7), 869-874, 2016 | 12 | 2016 |
DesigN and evaluation of engineered extracellular vesicle (EV)-based targeting for EGFR-overexpressing tumor cells using monobody display H Komuro, S Aminova, K Lauro, D Woldring, M Harada Bioengineering 9 (2), 56, 2022 | 11 | 2022 |
Proposed three-phenylalanine motif involved in magnetoreception signalling of an Actinopterygii protein expressed in mammalian cells B Ricker, S Mitra, EA Castellanos, CJ Grady, D Woldring, G Pelled, ... Open Biology 13 (11), 230019, 2023 | 8 | 2023 |
Protein fitness prediction is impacted by the interplay of language models, ensemble learning, and sampling methods M Mardikoraem, D Woldring Pharmaceutics 15 (5), 1337, 2023 | 8 | 2023 |
Generative models for protein sequence modeling: recent advances and future directions M Mardikoraem, Z Wang, N Pascual, D Woldring Briefings in Bioinformatics 24 (6), bbad358, 2023 | 6 | 2023 |
Machine Learning-Driven Protein Library Design: A Path Toward Smarter Libraries M Mardikoraem, D Woldring Yeast Surface Display, 87-104, 2022 | 3 | 2022 |
Phytochemical drug discovery for COVID-19 using high-resolution computational docking and machine learning assisted binder prediction Z Wang, T Belecciu, J Eaves, M Reimers, MH Bachmann, D Woldring Journal of Biomolecular Structure and Dynamics 41 (14), 6643-6663, 2023 | 2 | 2023 |
Topological deep learning based deep mutational scanning J Chen, DR Woldring, F Huang, X Huang, GW Wei Computers in Biology and Medicine 164, 107258, 2023 | 2 | 2023 |
Ancestral Sequence Reconstruction and Alternate Amino Acid States Guide Protein Library Design for Directed Evolution J VanAntwerp, P Finneran, B Dolgikh, D Woldring Yeast Surface Display, 75-86, 2022 | 2 | 2022 |
Site-wise Diversification of Combinatorial Libraries Using Insights from Structure-guided StabilityStabilities Calculations B Dolgikh, D Woldring Yeast Surface Display, 63-73, 2022 | 2 | 2022 |
AP-LASR: Automated Protein Libraries from Ancestral Sequence Reconstruction J VanAntwerp, M Mardikoraem, N Pascual, D Woldring bioRxiv, 2023.10. 09.561537, 2023 | 1 | 2023 |
Evaluation of High Affinity Scaffolds from High-Throughput Discovery and Targeting DR5 and TNFR1 TL Senkow, DR Woldring, M Kruziki, BJ Hackel, JN Sachs Biophysical Journal 112 (3), 530a, 2017 | 1 | 2017 |
Machine Learning Based Protein Engineering D Woldring, L Stern 2023 AIChE Annual Meeting, 2023 | | 2023 |
Computational, Structure, Biophysical Protein Engineering D Woldring, P Jain 2023 AIChE Annual Meeting, 2023 | | 2023 |
Single-Cell B-Cell Sequencing to Generate Natively Paired scFab Yeast Surface Display Libraries N Pascual, T Belecciu, S Schmidt, A Nakisa, X Huang, D Woldring Genotype Phenotype Coupling: Methods and Protocols, 175-212, 2023 | | 2023 |