Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference K Xiong, KF Marquart, KJ la Cour Karottki, S Li, I Shamie, JS Lee, ... Biotechnology and bioengineering 116 (7), 1813-1819, 2019 | 45 | 2019 |
Awakening dormant glycosyltransferases in CHO cells with CRISPRa KJC Karottki, H Hefzi, K Xiong, I Shamie, AH Hansen, S Li, LE Pedersen, ... Biotechnology and bioengineering 117 (2), 593-598, 2020 | 36 | 2020 |
Application of CRISPR/Cas9 genome editing to improve recombinant protein production in CHO cells LM Grav, KJ la Cour Karottki, JS Lee, HF Kildegaard Heterologous Protein Production in CHO Cells: Methods and Protocols, 101-118, 2017 | 32 | 2017 |
An optimized genome-wide, virus-free CRISPR screen for mammalian cells K Xiong, KJ la Cour Karottki, H Hefzi, S Li, LM Grav, S Li, P Spahn, JS Lee, ... Cell Reports Methods 1 (4), 2021 | 20 | 2021 |
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes KJ la Cour Karottki, H Hefzi, S Li, LE Pedersen, PN Spahn, C Joshi, ... Metabolic engineering 66, 114-122, 2021 | 20 | 2021 |
A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells I Shamie, SH Duttke, KJC Karottki, CZ Han, AH Hansen, H Hefzi, K Xiong, ... NAR genomics and bioinformatics 3 (3), lqab061, 2021 | 11 | 2021 |
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium TK Ha, A Òdena, KJC Karottki, CL Kim, H Hefzi, GM Lee, ... Biotechnology and Bioengineering 120 (4), 1159-1166, 2023 | 4 | 2023 |
CRISPR Toolbox for mammalian cell engineering D Sergeeva, KJ la Cour Karottki, JS Lee, HF Kildegaard Cell Culture Engineering: Recombinant Protein Production, 185-206, 2019 | 3 | 2019 |
Identification of hyperosmotic stress-responsive genes in Chinese hamster ovary cells via genome-wide virus-free CRISPR/Cas9 screening SH Kim, S Shin, M Baek, K Xiong, KJ la Cour Karottki, H Hefzi, LM Grav, ... Metabolic Engineering 80, 66-77, 2023 | 2 | 2023 |
Using targeted genome integration for virus-free genome-wide mammalian CRISPR screen K Xiong, KJC Karottki, H Hefzi, S Li, LM Grav, S Li, P Spahn, JS Lee, ... bioRxiv, 2020.05. 19.103648, 2020 | 2 | 2020 |
From observational to actionable: rethinking omics in biologics production HO Masson, KJ la Cour Karottki, J Tat, H Hefzi, NE Lewis Trends in Biotechnology, 2023 | 1 | 2023 |
Genome-Wide Virus-Free CRISPR/Cas9 Screening in CHO Cells: Improving Resistance to Hyperosmotic Stress SH KIM, S Seunghyeon, B Minhye, K XIONG, KJ la Cour KAROTTKI, ... 한국생물공학회 학술대회, 678-678, 2023 | | 2023 |
Asparaginase Based Selection System for Heterologous Protein Expression in Mammalian Cells H Hefzi, NE Lewis, KJ la Cour Karottki, HF Kildegaard US Patent App. 17/738,896, 2022 | | 2022 |
Expanding the CRISPR Toolbox for Chinese Hamster Ovary Cell Line Engineering KJ la Cour Karottki Technical University of Denmark, 2019 | | 2019 |
CB-05THE ROLE OF Emb-5 IN GLIOBLASTOMA MAINTENANCE AND THERAPEUTIC RESISTANCE RD Rasmussen, KE Jensen, MK Gajjar, KJ la Cour Karottki, J Bartek Jr, ... Neuro-Oncology 16 (Suppl 5), v42, 2014 | | 2014 |