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Tahnee Dening
Tahnee Dening
Principal Scientist at Genentech
Verified email at gene.com
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Cited by
Cited by
Year
Solidification to improve the biopharmaceutical performance of SEDDS: Opportunities and challenges
P Joyce, TJ Dening, TR Meola, HB Schultz, R Holm, N Thomas, ...
Advanced drug delivery reviews 142, 102-117, 2019
982019
Novel nanostructured solid materials for modulating oral drug delivery from solid-state lipid-based drug delivery systems
TJ Dening, S Rao, N Thomas, CA Prestidge
The AAPS journal 18, 23-40, 2016
712016
Oral nanomedicine approaches for the treatment of psychiatric illnesses
TJ Dening, S Rao, N Thomas, CA Prestidge
Journal of Controlled Release 223, 137-156, 2016
562016
Supersaturation potential of ordered mesoporous silica delivery systems. Part 1: Dissolution performance and drug membrane transport rates
TJ Dening, LS Taylor
Molecular Pharmaceutics 15 (8), 3489-3501, 2018
442018
Nanostructured montmorillonite clay for controlling the lipase-mediated digestion of medium chain triglycerides
TJ Dening, P Joyce, S Rao, N Thomas, CA Prestidge
ACS applied materials & interfaces 8 (48), 32732-32742, 2016
412016
Silica encapsulated lipid-based drug delivery systems for reducing the fed/fasted variations of ziprasidone in vitro
TJ Dening, S Rao, N Thomas, CA Presidge
European Journal of Pharmaceutics and Biopharmaceutics, 2016
362016
Application of an adsorption isotherm to explain incomplete drug release from ordered mesoporous silica materials under supersaturating conditions
TJ Dening, D Zemlyanov, LS Taylor
Journal of controlled release 307, 186-199, 2019
312019
Montmorillonite-lipid hybrid carriers for ionizable and neutral poorly water-soluble drugs: Formulation, characterization and in vitro lipolysis studies
TJ Dening, S Rao, N Thomas, CA Prestidge
International Journal of Pharmaceutics 526 (1-2), 95-105, 2017
302017
Montmorillonite and Laponite clay materials for the solidification of lipid-based formulations for the basic drug Blonanserin: in vitro and in vivo investigations
TJ Dening, N Thomas, S Rao, C Van Looveren, F Cuyckens, R Holm, ...
Molecular pharmaceutics 15 (9), 4148-4160, 2018
242018
Spray dried smectite clay particles as a novel treatment against obesity
TJ Dening, P Joyce, M Kovalainen, H Gustafsson, CA Prestidge
Pharmaceutical Research 36, 1-14, 2019
172019
Improving correlations between drug solubilization and in vitro lipolysis by monitoring the phase partitioning of lipolytic species for lipid-based formulations
TJ Dening, P Joyce, CA Prestidge
Journal of Pharmaceutical Sciences 108 (1), 295-304, 2019
162019
Inorganic surface chemistry and nanostructure controls lipolytic product speciation and partitioning during the digestion of inorganic-lipid hybrid particles
TJ Dening, P Joyce, JL Webber, DA Beattie, CA Prestidge
Journal of colloid and interface science 532, 666-679, 2018
162018
Nanocrystal-silica-lipid hybrid particles for the improved oral delivery of ziprasidone in vitro
TR Meola, TJ Dening, CA Prestidge
European Journal of Pharmaceutics and Biopharmaceutics 129, 145-153, 2018
162018
Modulating the Lipase‐Mediated Bioactivity of Particle‐Lipid Conjugates Through Changes in Nanostructure and Surface Chemistry
P Joyce, TJ Dening, H Gustafsson, CA Prestidge
European journal of lipid science and technology 119 (12), 1700213, 2017
122017
Nanostructured clay particles supplement orlistat action in inhibiting lipid digestion: An in vitro evaluation for the treatment of obesity
P Joyce, TJ Dening, TR Meola, H Gustafsson, M Kovalainen, ...
European Journal of Pharmaceutical Sciences 135, 1-11, 2019
112019
Contrasting anti-obesity effects of smectite clays and mesoporous silica in Sprague-Dawley rats
P Joyce, TJ Dening, TR Meola, A Wignall, H Ulmefors, M Kovalainen, ...
ACS Applied Bio Materials 3 (11), 7779-7788, 2020
82020
In vitro performance and chemical stability of lipid-based formulations encapsulated in a mesoporous magnesium carbonate carrier
C Alvebratt, TJ Dening, M Åhlén, O Cheung, M Strømme, A Gogoll, ...
Pharmaceutics 12 (5), 426, 2020
72020
Do Macrocyclic Peptide Drugs Interact with Bile Salts under Simulated Gastrointestinal Conditions?
TJ Dening, JT Douglas, MJ Hageman
Molecular Pharmaceutics 18 (8), 3086-3098, 2021
52021
Biorelevant dissolution method considerations for the appropriate evaluation of amorphous solid dispersions: are two stages necessary?
Z Wang, H Lou, TJ Dening, MJ Hageman
Journal of Pharmaceutical Sciences 112 (4), 1089-1107, 2023
42023
Enhancing intestinal absorption of a model macromolecule via the paracellular pathway using E-Cadherin peptides
TJ Dening, TJ Siahaan, MJ Hageman
Journal of Pharmaceutical Sciences 110 (5), 2139-2148, 2021
22021
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