Aldose reductase enzyme and its implication to major health problems of the 21st century P Alexiou, K Pegklidou, M Chatzopoulou, I Nicolaou, VJ Demopoulos Current medicinal chemistry 16 (6), 734-752, 2009 | 268 | 2009 |
RAGE: a multi-ligand receptor unveiling novel insights in health and disease P Alexiou, M Chatzopoulou, K Pegklidou, VJ Demopoulos Current medicinal chemistry 17 (21), 2232-2252, 2010 | 176 | 2010 |
Curcumin derivatives as photosensitizers in photodynamic therapy: photophysical properties and in vitro studies with prostate cancer cells KT Kazantzis, K Koutsonikoli, B Mavroidi, M Zachariadis, P Alexiou, ... Photochemical & Photobiological Sciences 19, 193-206, 2020 | 96 | 2020 |
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity P Alexiou, VJ Demopoulos Journal of medicinal chemistry 53 (21), 7756-7766, 2010 | 70 | 2010 |
The aldose reductase inhibitory capacity of Sorbus domestica fruit extracts depends on their phenolic content and may be useful for the control of diabetic complications A Termentzi, P Alexiou, VJ Demopoulos, E Kokkalou Die Pharmazie-An International Journal of Pharmaceutical Sciences 63 (9 …, 2008 | 62 | 2008 |
Synthesis of hydroxyapatite, β-tricalcium phosphate and biphasic calcium phosphate particles to act as local delivery carriers of curcumin: loading, release and in vitro studies D Xidaki, P Agrafioti, D Diomatari, A Kaminari, E Tsalavoutas-Psarras, ... Materials 11 (4), 595, 2018 | 52 | 2018 |
Novel aldose reductase inhibitors: a patent survey (2006–present) M Chatzopoulou, P Alexiou, E Kotsampasakou, VJ Demopoulos Expert opinion on therapeutic patents 22 (11), 1303-1323, 2012 | 51 | 2012 |
Novel curcumin derivatives as P-glycoprotein inhibitors: Molecular modeling, synthesis and sensitization of multidrug resistant cells to doxorubicin M Sagnou, FN Novikov, ES Ivanova, P Alexiou, VS Stroylov, IY Titov, ... European Journal of Medicinal Chemistry 198, 112331, 2020 | 37 | 2020 |
Rationally designed less toxic SPD‐304 analogs and preliminary evaluation of their TNF inhibitory effects P Alexiou, A Papakyriakou, E Ntougkos, CP Papaneophytou, F Liepouri, ... Archiv der Pharmazie 347 (11), 798-805, 2014 | 30 | 2014 |
Design and synthesis of N-(3, 5-difluoro-4-hydroxyphenyl) benzenesulfonamides as aldose reductase inhibitors P Alexiou, I Nicolaou, M Stefek, A Kristl, VJ Demopoulos Bioorganic & medicinal chemistry 16 (7), 3926-3932, 2008 | 26 | 2008 |
Compounds that combine aldose reductase inhibitory activity and ability to prevent the glycation (glucation and/or fructation) of proteins as putative pharmacotherapeutic agents VJ Demopoulos, N Zaher, C Zika, C Anagnostou, E Mamadou, P Alexiou, ... Drug Design Reviews-Online (Discontinued) 2 (4), 293-304, 2005 | 23 | 2005 |
Medicinal plants used for the treatment of diabetes and its long-term complications P Alexiou, VJ Demopoulos Plants in Traditional and Modern Medicine: Chemistry and Activity 69, 175, 2010 | 22 | 2010 |
Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit morphine's rewarding effect in rats V Katsidoni, P Alexiou, M Fotiadou, M Pelecanou, M Sagnou, G Panagis Psychopharmacology 231, 4467-4478, 2014 | 20 | 2014 |
Synthesis and biological evaluation of potential small molecule inhibitors of tumor necrosis factor C Papaneophytou, P Alexiou, A Papakyriakou, E Ntougkos, K Tsiliouka, ... MedChemComm 6 (6), 1196-1209, 2015 | 13 | 2015 |
Isatin thiosemicarbazones promote honeycomb structure formation in spin-coated polymer films: concentration effect and release studies VG Fernández-Luna, D Mallinson, P Alexiou, I Khadra, AB Mullen, ... RSC advances 7 (21), 12945-12952, 2017 | 8 | 2017 |
Discovery of small-molecule inhibitors of receptor activator of nuclear factor-κb ligand with a superior therapeutic index V Rinotas, A Papakyriakou, F Violitzi, C Papaneophytou, MD Ouzouni, ... Journal of medicinal chemistry 63 (20), 12043-12059, 2020 | 7 | 2020 |
Isatin thiosemicarbazone-blended polymer films for biomedical applications: surface morphology, characterisation and preliminary biological assessment D Mallinson, P Alexiou, AB Mullen, M Pelecanou, M Sagnou, DA Lamprou RSC advances 6 (30), 24939-24945, 2016 | 6 | 2016 |
A new neural network ensemble heuristic for a predictor of the aldose reductase inhibitory activity R Parra-Hernandez, EM Laxdal, NJ Dimopoulos, P Alexiou Proceedings of the Fifth IEEE International Symposium on Signal Processing …, 2005 | 6 | 2005 |
Aqueous Solubility Enhancement for Bioassays of Insoluble Inhibitors and QSPR Analysis: A TNF-α Study A Mettou, C Papaneophytou, G Melagraki, A Maranti, F Liepouri, ... SLAS DISCOVERY: Advancing Life Sciences R&D 23 (1), 84-93, 2018 | 4 | 2018 |
Antiradical efficiency and aldose reductase inhibitory capacity of Cornelian cherry (Cornus mas L.) fruits' extracts P Tsatalas, P Alexiou, V Demopoulos, E Kokkalou Planta Medica 74 (09), PH28, 2008 | 1 | 2008 |