Margarita Zachariou

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Prof. George M. SpyrouProfessor, Bioinformatics Chair and Department Head, Bioinformatics Department, CINGVerified email at cing.ac.cy
Anastasis OulasAssociate Scientist at The Cyprus Institute of Neurology and Genetics (CING)Verified email at cing.ac.cy
George MinadakisThe Cyprus Institute of Neurology and Genetics (CING)Verified email at cing.ac.cy
Marilena BourdakouPostdoctoral Fellow and Visiting Scientist at Cyprus Institute of Neurology and GeneticsVerified email at cing.ac.cy
Stephen CoombesUniversity of NottinghamVerified email at nottingham.ac.uk
Marios TomazouAssociate scientist, Institute of Neurology and GeneticsVerified email at cing.ac.cy
Dilshani WN DissanayakeNeuroscientist, Senior Lecturer, Faculty of Medicine, University of ColomboVerified email at physiol.cmb.ac.lk
Kleitos SokratousOMass TherapeuticsVerified email at omass.com
Nikolaos DietisPharmacologist, Medical School University of CyprusVerified email at ucy.ac.cy
Christiana ChristodoulouThe Cyprus Institute of Neurology and GeneticsVerified email at cing.ac.cy
Evangelos KaratzasEMBL-EBI, Research FellowVerified email at ebi.ac.uk
Zamba EVerified email at cing.ac.cy
Chris ChristodoulouProfessor, Department of Computer Science, University of CyprusVerified email at cs.ucy.ac.cy
George Kolios, MD, Ph.D (Athens), Ph....Laboratory of Pharmacology, Faculty of Medicine, Democritus University of Thrace, Greece.Verified email at med.duth.gr
Bindi BrookProfessor of Mathematical Medicine and Biology, University of NottinghamVerified email at nottingham.ac.uk
Markus OwenProfessor of Mathematical Biology, University of NottinghamVerified email at nottingham.ac.uk
Steve AlexanderUniversity of NottinghamVerified email at nottingham.ac.uk
Peter KohlChair, Experimental Cardiovascular Medicine (IEKM), University Heart Ctr, University of Freiburg, DEVerified email at universitaets-herzzentrum.de
Dr Theodoros Kyprianou, Consultant,...Professor of Medicine (clinical track), University of Nicosia Medical SchoolVerified email at unic.ac.cy
Jan RichterCyprus institute of neurology and geneticsVerified email at cing.ac.cy

Margarita Zachariou

The Cyprus Institute of Neurology and Genetics

Verified email at cs.ucy.ac.cy - Homepage

Computational Neuroscience Systems Bioinformatics


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Systems bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches A Oulas, G Minadakis, M Zachariou, K Sokratous, MM Bourdakou, ... Briefings in bioinformatics 20 (3), 806-824, 2019	125	2019
Auditory gating in rat hippocampus and medial prefrontal cortex: effect of the cannabinoid agonist WIN55, 212-2 DWN Dissanayake, M Zachariou, CA Marsden, R Mason Neuropharmacology 55 (8), 1397-1404, 2008	45	2008
Integrating multi-source information on a single network to detect disease-related clusters of molecular mechanisms M Zachariou, G Minadakis, A Oulas, S Afxenti, GM Spyrou Journal of proteomics 188, 15-29, 2018	37	2018
PathwayConnector: finding complementary pathways to enhance functional analysis G Minadakis, M Zachariou, A Oulas, GM Spyrou Bioinformatics 35 (5), 889-891, 2019	32	2019
Generalized linear models provide a measure of virulence for specific mutations in SARS-CoV-2 strains A Oulas, M Zanti, M Tomazou, M Zachariou, G Minadakis, MM Bourdakou, ... PLoS One 16 (1), e0238665, 2021	31	2021
A biophysical model of endocannabinoid-mediated short term depression in hippocampal inhibition M Zachariou, SPH Alexander, S Coombes, C Christodoulou PloS one 8 (3), e58926, 2013	30	2013
Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19 M Tomazou, MM Bourdakou, G Minadakis, M Zachariou, A Oulas, ... Briefings in bioinformatics 22 (6), bbab114, 2021	28	2021
Investigating the transition of pre-symptomatic to symptomatic huntington’s disease status based on omics data CC Christodoulou, M Zachariou, M Tomazou, E Karatzas, CA Demetriou, ... International Journal of Molecular Sciences 21 (19), 7414, 2020	25	2020
Selecting variants of unknown significance through network-based gene-association significantly improves risk prediction for disease-control cohorts A Oulas, G Minadakis, M Zachariou, GM Spyrou Scientific Reports 9 (1), 3266, 2019	25	2019
Sensory gating and its modulation by cannabinoids: electrophysiological, computational and mathematical analysis M Zachariou, DWN Dissanayake, S Coombes, MR Owen, R Mason Cognitive neurodynamics 2, 159-170, 2008	21	2008
Age-related exosomal and endogenous expression patterns of miR-1, miR-133a, miR-133b, and miR-206 in skeletal muscles C Mytidou, A Koutsoulidou, M Zachariou, M Prokopi, K Kapnisis, ... Frontiers in physiology 12, 708278, 2021	20	2021
Revealing clusters of connected pathways through multisource data integration in huntington's disease and spastic ataxia AC Kakouri, CC Christodoulou, M Zachariou, A Oulas, G Minadakis, ... IEEE journal of biomedical and health informatics 23 (1), 26-37, 2018	20	2018
Virtual physiological human: training challenges PV Lawford, AV Narracott, K McCormack, J Bisbal, C Martin, B Brook, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2010	20	2010
Computational drug repurposing for neurodegenerative diseases K Savva, M Zachariou, A Oulas, G Minadakis, K Sokratous, N Dietis, ... In Silico Drug Design, 85-118, 2019	18	2019
Effects of phencyclidine on auditory gating in the rat hippocampus and the medial prefrontal cortex DWN Dissanayake, M Zachariou, CA Marsden, R Mason Brain research 1298, 153-160, 2009	17	2009
Gap junctions and emergent rhythms S Coombes, M Zachariou Coherent Behavior in Neuronal Networks, 77-94, 2009	17	2009
Network-based stage-specific drug repurposing for Alzheimer’s disease K Savva, M Zachariou, MM Bourdakou, N Dietis, GM Spyrou Computational and Structural Biotechnology Journal 20, 1427-1438, 2022	13	2022
Identifying novel osteoarthritis-associated genes in human cartilage using a systematic meta-analysis and a multi-source integrated network E Shorter, R Avelar, M Zachariou, GM Spyrou, P Raina, A Smagul, ... International Journal of Molecular Sciences 23 (8), 4395, 2022	11	2022
The role of cannabinoids in the neurobiology of sensory gating: A firing rate model study M Zachariou, DWN Dissanayake, MR Owen, R Mason, S Coombes Neurocomputing 70 (10-12), 1902-1906, 2007	11	2007
PathWalks: Identifying pathway communities using a disease-related map of integrated information E Karatzas, M Zachariou, MM Bourdakou, G Minadakis, A Oulas, G Kolios, ... Bioinformatics 36 (13), 4070-4079, 2020	9	2020

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