Παρακολούθηση
Stephen B. Keysar PhD
Stephen B. Keysar PhD
Associate Research Professor, University of Colorado School of Medicine
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα ucdenver.edu - Αρχική σελίδα
Τίτλος
Παρατίθεται από
Παρατίθεται από
Έτος
An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101
RC Doebele, LE Davis, A Vaishnavi, AT Le, A Estrada-Bernal, S Keysar, ...
Cancer discovery 5 (10), 1049-1057, 2015
410*2015
More than markers: biological significance of cancer stem cell-defining molecules
SB Keysar, A Jimeno
Molecular cancer therapeutics 9 (9), 2450-2457, 2010
2502010
A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins
SB Keysar, DP Astling, RT Anderson, BW Vogler, DW Bowles, JJ Morton, ...
Molecular oncology 7 (4), 776-790, 2013
1712013
XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer
JJ Morton, G Bird, SB Keysar, DP Astling, TR Lyons, RT Anderson, ...
Oncogene 35 (3), 290-300, 2016
1332016
Cancer cell CD44 mediates macrophage/monocyte-driven regulation of head and neck cancer stem cells
KE Gomez, FL Wu, SB Keysar, JJ Morton, B Miller, TS Chimed, PN Le, ...
Cancer research 80 (19), 4185-4198, 2020
1212020
Regulation of head and neck squamous cancer stem cells by PI3K and SOX2
SB Keysar, PN Le, B Miller, BC Jackson, JR Eagles, C Nieto, J Kim, ...
Journal of the National Cancer Institute 109 (1), djw189, 2017
1212017
Epithelial stem cell mutations that promote squamous cell carcinoma metastasis
RA White, JM Neiman, A Reddi, G Han, S Birlea, D Mitra, L Dionne, ...
The Journal of clinical investigation 123 (10), 4390-4404, 2013
1042013
Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer
SB Keysar, PN Le, RT Anderson, JJ Morton, DW Bowles, JJ Paylor, ...
Cancer research 73 (11), 3381-3392, 2013
1042013
EGFR mediates responses to small-molecule drugs targeting oncogenic fusion kinases
A Vaishnavi, L Schubert, U Rix, LA Marek, AT Le, SB Keysar, ...
Cancer research 77 (13), 3551-3563, 2017
772017
Hedgehog signaling drives radioresistance and stroma-driven tumor repopulation in head and neck squamous cancers
GN Gan, J Eagles, SB Keysar, G Wang, MJ Glogowska, C Altunbas, ...
Cancer research 74 (23), 7024-7036, 2014
732014
Phase I study of oral rigosertib (ON 01910. Na), a dual inhibitor of the PI3K and Plk1 pathways, in adult patients with advanced solid malignancies
DW Bowles, JR Diamond, ET Lam, CD Weekes, DP Astling, RT Anderson, ...
Clinical Cancer Research 20 (6), 1656-1665, 2014
702014
Wnt signaling dynamics in head and neck squamous cell cancer tumor‐stroma interactions
PN Le, SB Keysar, B Miller, JR Eagles, TS Chimed, J Reisinger, ...
Molecular carcinogenesis 58 (3), 398-410, 2019
562019
A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer
JJ Arcaroli, WM Tai, R McWilliams, S Bagby, PJ Blatchford, ...
International journal of cancer 138 (1), 195-205, 2016
452016
A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma
DW Bowles, SB Keysar, JR Eagles, G Wang, MJ Glogowska, ...
Oral oncology 53, 74-79, 2016
402016
The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas
RT Anderson, SB Keysar, DW Bowles, MJ Glogowska, DP Astling, ...
Molecular cancer therapeutics 12 (10), 1994-2005, 2013
362013
Salivary gland cancer patient-derived xenografts enable characterization of cancer stem cells and new gene events associated with tumor progression
SB Keysar, JR Eagles, B Miller, BC Jackson, FN Chowdhury, J Reisinger, ...
Clinical Cancer Research 24 (12), 2935-2943, 2018
302018
Comparison of the mutagenic potential of 17 physical and chemical agents analyzed by the flow cytometry mutation assay
CT French, CD Ross, SB Keysar, DD Joshi, CU Lim, MH Fox
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 602 (1 …, 2006
302006
Inter‐ and intra‐tumor heterogeneity of SMAD4 loss in head and neck squamous cell carcinomas
AL Hernandez, Y Wang, HL Somerset, SB Keysar, DL Aisner, C Marshall, ...
Molecular carcinogenesis 58 (5), 666-673, 2019
262019
Dual use of hematopoietic and mesenchymal stem cells enhances engraftment and immune cell trafficking in an allogeneic humanized mouse model of head and neck cancer
JJ Morton, SB Keysar, L Perrenoud, TS Chimed, J Reisinger, B Jackson, ...
Molecular carcinogenesis 57 (11), 1651-1663, 2018
222018
DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation
CP Allen, W Tinganelli, N Sharma, J Nie, C Sicard, F Natale, M King III, ...
Frontiers in oncology 5, 260, 2015
222015
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