| Genetic determinants of childhood obesity SH Littleton, RI Berkowitz, SFA Grant Molecular diagnosis & therapy 24 (6), 653-663, 2020 | 97 | 2020 |
| Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits MC Pahl, CA Doege, KM Hodge, SH Littleton, ME Leonard, S Lu, ... Nature communications 12 (1), 6749, 2021 | 22 | 2021 |
| Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2 SH Littleton, KB Trang, CM Volpe, K Cook, N DeBruyne, JA Maguire, ... Cell Genomics 4 (5), 2024 | 4 | 2024 |
| 3D genomic features across> 50 diverse cell types reveal insights into the genomic architecture of childhood obesity KB Trang, MC Pahl, JA Pippin, C Su, SH Littleton, P Sharma, NN Kulkarni, ... medRxiv, 2024 | 3 | 2024 |
| Perturbation of the insomnia WDR90 GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q S Sonti, SH Littleton, MC Pahl, AJ Zimmerman, A Chesi, J Palermo, ... bioRxiv, 2023 | 3 | 2023 |
| Strategies to identify causal common genetic variants and corresponding effector genes for paediatric obesity SH Littleton, SFA Grant Pediatric Obesity 17 (12), e12968, 2022 | 2 | 2022 |
| Metabolic links among milk, genes and gut SH Littleton, SFA Grant Nature Metabolism 6 (1), 12-13, 2024 | 1 | 2024 |
| 298-OR: Variant-to-Gene Mapping at the Childhood Obesity Locus on chr12q13 and Subsequent Luciferase Assay Analyses Implicate rs71329as a Causal Variant within the 3˘UTR of FAIM2 SH Littleton, J Bradfield, JA Pippin, C Su, A Chesi, AD Wells, RI Berkowitz, ... Diabetes 71 (Supplement_1), 2022 | 1 | 2022 |
| Protocol to study cis-regulatory activity of GWAS loci for specific gene promoters in human primary astrocytes using luciferase reporter assay SH Littleton, SFA Grant STAR protocols 5 (4), 103338, 2024 | | 2024 |
| Perturbation of the insomnia WDR90 genome-wide association studies locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q S Sonti, SH Littleton, MC Pahl, AJ Zimmerman, A Chesi, J Palermo, ... Sleep, zsae085, 2024 | | 2024 |
| Variant-to-function mapping of late-onset Alzheimer˘s disease GWAS signals in human microglial cell models implicates RTFDC1 at the CASS4 locus EA Burton, M Argenziano, K Cook, M Ridler, S Lu, C Su, E Manduchi, ... bioRxiv, 2024 | | 2024 |
| Investigating the FAIM2 locus in predisposition to childhood obesity SH Littleton University of Pennsylvania, 2024 | | 2024 |
| Validation of rs7132908 as a causal variant at the childhood obesity chr12q13 locus S Littleton, C Volpe, MA Hazuga, K Trang, N DeBruyne, JA Maguire, ... EUROPEAN JOURNAL OF HUMAN GENETICS 32, 734-735, 2024 | | 2024 |
| Variant-to-Function: rs7132908 at the FAIM2 Locus Influences Expression and Neuron Differentiation S Littleton, C Volpe, K Cook, MA Weidekamp, K Boehm, J Pippin Obesity 31, 35-36, 2023 | | 2023 |
| Validation of rs7132908 as a Causal Variant at the Childhood Obesity chr12q13 Locus Implicates FAIM2 S Littleton, C Volpe, J Bradfield, J Pippin, R Berkowitz Obesity 30, 40-41, 2022 | | 2022 |
| Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant common complex traits SH Littleton, MC Pahl, CA Doege, KM Hodge, ME Leonard, S Lu, ... EUROPEAN JOURNAL OF HUMAN GENETICS 28 (SUPPL 1), 996-996, 2020 | | 2020 |
| 245-OR: CIS-Regulatory Architecture of Human ESC-Derived Hypothalamic Neuron Differentiation Aids in Variant-to-Gene Mapping of Type 2 Diabetes Related Traits MC PAHL, SH LITTLETON, C DOEGE, KM HODGE, M LEONARD, S LU, ... Diabetes 69 (Supplement_1), 2020 | | 2020 |
| High Resolution Genome-wide Promoter-focused Connectome Implicates Microglia Causal Genes for Alzheimer˘s Disease M Argenziano, E Manduchi, S Littleton, ME Leonard, C Su, S Lu, ... Alzheimer's & Dementia 15 (7), P238, 2019 | | 2019 |
