Bioinformatic analysis of a PLP-dependent enzyme superfamily suitable for biocatalytic applications F Steffen-Munsberg, C Vickers, H Kohls, H Land, H Mallin, A Nobili, ... Biotechnology advances 33 (5), 566-604, 2015 | 185 | 2015 |
Drug design for ever, from hype to hope G Seddon, V Lounnas, R McGuire, T van den Bergh, RP Bywater, ... Journal of computer-aided molecular design 26 (1), 137-150, 2012 | 53 | 2012 |
Engineering the Amine Transaminase from Vibrio fluvialis towards Branched‐Chain Substrates M Genz, O Melse, S Schmidt, C Vickers, M Dörr, T Van Den Bergh, ... ChemCatChem 8 (20), 3199-3202, 2016 | 43 | 2016 |
Switch in cofactor specificity of a baeyer–villiger monooxygenase A Beier, S Bordewick, M Genz, S Schmidt, T Van Den Bergh, C Peters, ... ChemBioChem 17 (24), 2312-2315, 2016 | 41 | 2016 |
A structural classification of carbohydrate epimerases: from mechanistic insights to practical applications S Van Overtveldt, T Verhaeghe, HJ Joosten, T van den Bergh, K Beerens, ... Biotechnology Advances 33 (8), 1814-1828, 2015 | 35 | 2015 |
Alteration of the Donor/Acceptor Spectrum of the (S)-Amine Transaminase from Vibrio fluvialis M Genz, C Vickers, T Van den Bergh, HJ Joosten, M Dörr, M Höhne, ... International journal of molecular sciences 16 (11), 26953-26963, 2015 | 34 | 2015 |
Novel tools for extraction and validation of disease‐related mutations applied to fabry disease R Kuipers, T van den Bergh, HJ Joosten, RH Lekanne dit Deprez, ... Human mutation 31 (9), 1026-1032, 2010 | 30 | 2010 |
Simultaneous use of in silico design and a correlated mutation network as a tool to efficiently guide enzyme engineering A Nobili, Y Tao, IV Pavlidis, T van den Bergh, HJ Joosten, T Tan, ... ChemBioChem 16 (5), 805-810, 2015 | 26 | 2015 |
Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily E Lanfranchi, T Pavkov-Keller, EM Koehler, M Diepold, K Steiner, ... Scientific reports 7 (1), 1-15, 2017 | 24 | 2017 |
CorNet: Assigning function to networks of co-evolving residues by automated literature mining T Van Den Bergh, G Tamo, A Nobili, Y Tao, T Tan, UT Bornscheuer, ... PLoS One 12 (5), e0176427, 2017 | 11 | 2017 |
Going to extremes–a metagenomic journey into the dark matter of life A Aevarsson, AK Kaczorowska, BT Adalsteinsson, J Ahlqvist, ... FEMS microbiology letters 368 (12), fnab067, 2021 | 9 | 2021 |
Mind the gap: preventing circularity in missense variant prediction S Heijl, B Vroling, T van den Bergh, HJ Joosten BioRxiv, 2020 | 4 | 2020 |
Bioinformatic analysis of fold-type III PLP-dependent enzymes discovers multimeric racemases AM Knight, A Nobili, T van den Bergh, M Genz, HJ Joosten, D Albrecht, ... Applied microbiology and biotechnology 101 (4), 1499-1507, 2017 | 3 | 2017 |
Towards a better understanding of proteins through protein-family data integration T van den Bergh PQDT-Global, 2022 | | 2022 |
Erratum: Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily E Lanfranchi, T Pavkov-Keller, EM Koehler, M Diepold, K Steiner, ... Scientific Reports 7, 2017 | | 2017 |
Common pitfalls and novel opportunities for predicting variant pathogenicity T van den Bergh, B Vroling, RKP Kuipers, HJ Joosten, G Vriend protein-family data integration., 57, 2016 | | 2016 |
Inherited arrhythmia syndromes, how to identify pathogenic mutations? B Vroling, T van den Bergh, M Alders, S Heijl, M Tanck, RLD Deprez, ... protein-family data integration., 95, 0 | | |
3DM Protein Engineering Super-Family systems applied to the P450 family HJ Joosten, R Kuipers, T Van den Bergh, G Vriend, P Schaap | | |