Juan Valcarcel
Juan Valcarcel
ICREA Research Professor, Center for Genomic Regulation
Verified email at crg.eu - Homepage
Title
Cited by
Cited by
Year
Alternative pre-mRNA splicing: the logic of combinatorial control
CWJ Smith, J Valcárcel
Trends in biochemical sciences 25 (8), 381-388, 2000
11352000
Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins
R Singh, J Valcarcel, MR Green
Science 268 (5214), 1173-1176, 1995
6251995
Alternative splicing and genome complexity
D Brett, H Pospisil, J Valcárcel, J Reich, P Bork
Nature genetics 30 (1), 29-30, 2002
6192002
Nucleosome positioning as a determinant of exon recognition
H Tilgner, C Nikolaou, S Althammer, M Sammeth, M Beato, J Valcárcel, ...
Nature structural & molecular biology 16 (9), 996-1001, 2009
4772009
Synonymous mutations frequently act as driver mutations in human cancers
F Supek, B Miñana, J Valcárcel, T Gabaldón, B Lehner
Cell 156 (6), 1324-1335, 2014
4582014
The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA
J Valcárcel, R Singh, PD Zamore, MR Green
Nature 362 (6416), 171-175, 1993
4461993
The spliceosome as a target of novel antitumour drugs
S Bonnal, L Vigevani, J Valcárcel
Nature reviews Drug discovery 11 (11), 847-859, 2012
4042012
Optimization of oligonucleotide-based DNA microarrays
A Relógio, C Schwager, A Richter, W Ansorge, J Valcárcel
Nucleic acids research 30 (11), e51-e51, 2002
3942002
Regulation of Fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition
JM Izquierdo, N Majós, S Bonnal, C Martínez, R Castelo, R Guigó, ...
Molecular cell 19 (4), 475-484, 2005
3832005
Interaction of U2AF65 RS region with pre-mRNA of branch point and promotion base pairing with U2 snRNA
J Valcárcel, RK Gaur, R Singh, MR Green
Science 273 (5282), 1706-1709, 1996
3551996
The SR protein family: pleiotropic functions in pre-mRNA splicing
J Valcárcel, MR Green
Trends in biochemical sciences 21 (8), 296-301, 1996
3311996
Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF 35 and the 3′ splice site AG
L Merendino, S Guth, D Bilbao, C Martínez, J Valcárcel
Nature 402 (6763), 838-841, 1999
3191999
The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing
P Förch, O Puig, N Kedersha, C Martínez, S Granneman, B Séraphin, ...
Molecular cell 6 (5), 1089-1098, 2000
3032000
U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction.
J Fleckner, M Zhang, J Valcarcel, MR Green
Genes & development 11 (14), 1864-1872, 1997
2991997
Post-transcriptional regulation: the dawn of PTB
J Valcárcel, F Gebauer
Current Biology 7 (11), R705-R708, 1997
2381997
RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation
EG Bechara, E Sebestyén, I Bernardis, E Eyras, J Valcárcel
Molecular cell 52 (5), 720-733, 2013
2362013
Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A
A Corrionero, B Miñana, J Valcárcel
Genes & development 25 (5), 445-459, 2011
2332011
Building specificity with nonspecific RNA-binding proteins
R Singh, J Valcárcel
Nature structural & molecular biology 12 (8), 645-653, 2005
2302005
The splicing regulator TIA‐1 interacts with U1‐C to promote U1 snRNP recruitment to 5′ splice sites
P Förch, O Puig, C Martínez, B Séraphin, J Valcárcel
The EMBO journal 21 (24), 6882-6892, 2002
2232002
The hnRNP A1 protein regulates HIV‐1 tat splicing via a novel intron silencer element
TØ Tange, CK Damgaard, S Guth, J Valcárcel, J Kjems
The EMBO journal 20 (20), 5748-5758, 2001
2152001
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Articles 1–20