Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer RC Gimple, S Bhargava, D Dixit, JN Rich Genes & development 33 (11-12), 591-609, 2019 | 411 | 2019 |
The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells D Dixit, BC Prager, RC Gimple, HX Poh, Y Wang, Q Wu, Z Qiu, RL Kidwell, ... Cancer discovery 11 (2), 480-499, 2021 | 247 | 2021 |
Reciprocal signaling between glioblastoma stem cells and differentiated tumor cells promotes malignant progression X Wang, BC Prager, Q Wu, LJY Kim, RC Gimple, Y Shi, K Yang, ... Cell stem cell 22 (4), 514-528. e5, 2018 | 221 | 2018 |
Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions M Tang, Q Xie, RC Gimple, Z Zhong, T Tam, J Tian, RL Kidwell, Q Wu, ... Cell research 30 (10), 833-853, 2020 | 196 | 2020 |
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma TE Miller, BB Liau, LC Wallace, AR Morton, Q Xie, D Dixit, DC Factor, ... Nature 547 (7663), 355-359, 2017 | 195 | 2017 |
Targeting glioblastoma stem cells through disruption of the circadian clock Z Dong, G Zhang, M Qu, RC Gimple, Q Wu, Z Qiu, BC Prager, X Wang, ... Cancer discovery 9 (11), 1556-1573, 2019 | 189 | 2019 |
Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition D Dixit, V Sharma, S Ghosh, VS Mehta, E Sen Cell death & disease 3 (2), e271-e271, 2012 | 144 | 2012 |
Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma F Ahmad, D Dixit, V Sharma, A Kumar, SD Joshi, C Sarkar, E Sen Cell death & disease 7 (5), e2213-e2213, 2016 | 106 | 2016 |
Chaetocin-induced ROS-mediated apoptosis involves ATM–YAP1 axis and JNK-dependent inhibition of glucose metabolism D Dixit, R Ghildiyal, NP Anto, E Sen Cell death & disease 5 (5), e1212-e1212, 2014 | 97 | 2014 |
Ras regulates interleukin-1β-induced HIF-1α transcriptional activity in glioblastoma V Sharma, D Dixit, N Koul, VS Mehta, E Sen Journal of molecular medicine 89, 123-136, 2011 | 94 | 2011 |
Manumycin inhibits STAT3, telomerase activity, and growth of glioma cells by elevating intracellular reactive oxygen species generation D Dixit, V Sharma, S Ghosh, N Koul, PK Mishra, E Sen Free Radical Biology and Medicine 47 (4), 364-374, 2009 | 88 | 2009 |
IGF-1 induced HIF-1α-TLR9 cross talk regulates inflammatory responses in glioma S Sinha, N Koul, D Dixit, V Sharma, E Sen Cellular signalling 23 (11), 1869-1875, 2011 | 60 | 2011 |
HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity V Sharma, N Koul, C Joseph, D Dixit, S Ghosh, E Sen Journal of cellular and molecular medicine 14 (8), 2151-2161, 2010 | 60 | 2010 |
COX-2 regulates the proliferation of glioma stem like cells V Sharma, D Dixit, S Ghosh, E Sen Neurochemistry international 59 (5), 567-571, 2011 | 54 | 2011 |
Messenger RNA methylation regulates glioblastoma tumorigenesis D Dixit, Q Xie, JN Rich, JC Zhao Cancer cell 31 (4), 474-475, 2017 | 46 | 2017 |
Guggulsterone sensitizes glioblastoma cells to Sonic hedgehog inhibitor SANT-1 induced apoptosis in a Ras/NFκB dependent manner D Dixit, R Ghildiyal, NP Anto, S Ghosh, V Sharma, E Sen Cancer letters 336 (2), 347-358, 2013 | 43 | 2013 |
The meningioma enhancer landscape delineates novel subgroups and drives druggable dependencies BC Prager, HN Vasudevan, D Dixit, JA Bernatchez, Q Wu, LC Wallace, ... Cancer discovery 10 (11), 1722-1741, 2020 | 42 | 2020 |
β2-microglobulin maintains glioblastoma stem cells and induces M2-like polarization of tumor-associated macrophages D Li, Q Zhang, L Li, K Chen, J Yang, D Dixit, RC Gimple, S Ci, C Lu, L Hu, ... Cancer Research 82 (18), 3321-3334, 2022 | 40 | 2022 |
Regression of Dalton’s lymphoma in vivo via decline in lactate dehydrogenase and induction of apoptosis by a ruthenium (II)-complex containing 4-carboxy N-ethylbenzamide as ligand RK Koiri, SK Trigun, L Mishra, K Pandey, D Dixit, SK Dubey Investigational New Drugs 27, 503-516, 2009 | 39 | 2009 |
Transcription elongation machinery is a druggable dependency and potentiates immunotherapy in glioblastoma stem cells Z Qiu, L Zhao, JZ Shen, Z Liang, Q Wu, K Yang, L Min, RC Gimple, ... Cancer discovery 12 (2), 502-521, 2022 | 37 | 2022 |