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Joanna Holbrook
Joanna Holbrook
CSO, Cambridge Epigenetix
Verified email at cegx.co.uk - Homepage
Title
Cited by
Cited by
Year
Resistin is expressed in human macrophages and directly regulated by PPARã activators
L Patel, AC Buckels, IJ Kinghorn, PR Murdock, JD Holbrook, C Plumpton, ...
Biochemical and biophysical research communications 300 (2), 472-476, 2003
13352003
Cohort profile: Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study
SE Soh, MT Tint, PD Gluckman, KM Godfrey, A Rifkin-Graboi, YH Chan, ...
International journal of epidemiology 43 (5), 1401-1409, 2014
4512014
Applications of machine learning to diagnosis and treatment of neurodegenerative diseases
MA Myszczynska, PN Ojamies, AMB Lacoste, D Neil, A Saffari, R Mead, ...
Nature Reviews Neurology 16 (8), 440-456, 2020
3702020
The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes
AL Teh, H Pan, L Chen, ML Ong, S Dogra, J Wong, JL MacIsaac, SM Mah, ...
Genome research 24 (7), 1064-1074, 2014
3532014
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
N Kato, M Loh, F Takeuchi, N Verweij, X Wang, W Zhang, TN Kelly, ...
Nature genetics 47 (11), 1282-1293, 2015
3492015
Dynamics of infant gut microbiota are influenced by delivery mode and gestational duration and are associated with subsequent adiposity
S Dogra, O Sakwinska, SE Soh, C Ngom-Bru, WM Brück, B Berger, ...
MBio 6 (1), 10.1128/mbio. 02419-14, 2015
3332015
Human lymphocytes interact directly with CD47 through a novel member of the signal regulatory protein (SIRP) family
G Brooke, JD Holbrook, MH Brown, AN Barclay
The Journal of Immunology 173 (4), 2562-2570, 2004
1922004
Comprehensive predictive biomarker analysis for MEK inhibitor GSK1120212
J Jing, J Greshock, JD Holbrook, A Gilmartin, X Zhang, E McNeil, ...
Molecular cancer therapeutics 11 (3), 720-729, 2012
1452012
Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome
X Lin, IY Lim, Y Wu, AL Teh, L Chen, IM Aris, SE Soh, MT Tint, ...
BMC medicine 15, 1-18, 2017
1442017
The translational value of rodent gastrointestinal functions: a cautionary tale
GJ Sanger, JD Holbrook, PLR Andrews
Trends in pharmacological sciences 32 (7), 402-409, 2011
1192011
Rate of establishing the gut microbiota in infancy has consequences for future health
S Dogra, O Sakwinska, SE Soh, C Ngom-Bru, WM Brück, B Berger, ...
Gut microbes 6 (5), 321-325, 2015
1122015
Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine
JD Holbrook, JS Parker, KT Gallagher, WS Halsey, AM Hughes, ...
Journal of translational medicine 9, 1-13, 2011
1102011
COMT haplotypes modulate associations of antenatal maternal anxiety and neonatal cortical morphology
A Qiu, TA Tuan, ML Ong, Y Li, H Chen, A Rifkin-Graboi, BFP Broekman, ...
American Journal of Psychiatry 172 (2), 163-172, 2015
1052015
Effects of antenatal maternal depressive symptoms and socio-economic status on neonatal brain development are modulated by genetic risk
A Qiu, M Shen, C Buss, YS Chong, K Kwek, SM Saw, PD Gluckman, ...
Cerebral cortex 27 (5), 3080-3092, 2017
1042017
Characterisation of 5‐HT3C, 5‐HT3D and 5‐HT3E receptor subunits: evolution, distribution and function
JD Holbrook, CH Gill, N Zebda, JP Spencer, R Leyland, KH Rance, ...
Journal of neurochemistry 108 (2), 384-396, 2009
1012009
Identification of genes for the ghrelin and motilin receptors and a novel related gene in fish, and stimulation of intestinal motility in zebrafish (Danio rerio) by ghrelin and …
C Olsson, JD Holbrook, G Bompadre, E Jönsson, CHV Hoyle, GJ Sanger, ...
General and Comparative Endocrinology 155 (1), 217-226, 2008
982008
Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood
RC Huang, ES Garratt, H Pan, Y Wu, EA Davis, SJ Barton, GC Burdge, ...
Epigenetics 10 (11), 995-1005, 2015
972015
Novel region discovery method for Infinium 450K DNA methylation data reveals changes associated with aging in muscle and neuronal pathways
ML Ong, JD Holbrook
Aging cell 13 (1), 142-155, 2014
972014
Maternal smoking during pregnancy induces persistent epigenetic changes into adolescence, independent of postnatal smoke exposure and is associated with cardiometabolic risk
S Rauschert, PE Melton, G Burdge, JM Craig, KM Godfrey, JD Holbrook, ...
Frontiers in genetics 10, 468076, 2019
922019
Global DNA hypermethylation in down syndrome placenta
S Jin, YK Lee, YC Lim, Z Zheng, XM Lin, DPY Ng, JD Holbrook, HY Law, ...
PLoS genetics 9 (6), e1003515, 2013
922013
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