Παρακολούθηση
Jason E. Gestwicki
Jason E. Gestwicki
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα ucsf.edu
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Παρατίθεται από
Παρατίθεται από
Έτος
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13199*2021
Potential therapeutic applications of autophagy
DC Rubinsztein, JE Gestwicki, LO Murphy, DJ Klionsky
Nature reviews Drug discovery 6 (4), 304-312, 2007
12462007
Synthetic multivalent ligands as probes of signal transduction
LL Kiessling, JE Gestwicki, LE Strong
Angewandte Chemie International Edition 45 (15), 2348-2368, 2006
10112006
Influencing receptor− ligand binding mechanisms with multivalent ligand architecture
JE Gestwicki, CW Cairo, LE Strong, KA Oetjen, LL Kiessling
Journal of the American Chemical Society 124 (50), 14922-14933, 2002
9112002
Synthetic multivalent ligands in the exploration of cell-surface interactions
LL Kiessling, JE Gestwicki, LE Strong
Current opinion in chemical biology 4 (6), 696-703, 2000
7502000
Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate
EB Bertelsen, L Chang, JE Gestwicki, ERP Zuiderweg
Proceedings of the National Academy of Sciences 106 (21), 8471-8476, 2009
5672009
Heat shock protein 70 (hsp70) as an emerging drug target
CG Evans, L Chang, JE Gestwicki
Journal of medicinal chemistry 53 (12), 4585-4602, 2010
4992010
Heat shock proteins 70 and 90 inhibit early stages of amyloid β-(1–42) aggregation in vitro
CG Evans, S Wisén, JE Gestwicki
Journal of Biological Chemistry 281 (44), 33182-33191, 2006
4852006
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
SW Min, X Chen, TE Tracy, Y Li, Y Zhou, C Wang, K Shirakawa, ...
Nature medicine 21 (10), 1154-1162, 2015
4832015
Control of multivalent interactions by binding epitope density
CW Cairo, JE Gestwicki, M Kanai, LL Kiessling
Journal of the American Chemical Society 124 (8), 1615-1619, 2002
4722002
Structure–activity Relationships of amyloid beta‐aggregation inhibitors based on curcumin: influence of linker length and flexibility
AA Reinke, JE Gestwicki
Chemical biology & drug design 70 (3), 206-215, 2007
3962007
A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis
CP Chang, JR Neilson, JH Bayle, JE Gestwicki, A Kuo, K Stankunas, ...
Cell 118 (5), 649-663, 2004
3732004
Inter-receptor communication through arrays of bacterial chemoreceptors
JE Gestwicki, LL Kiessling
Nature 415 (6867), 81-84, 2002
3302002
Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo
EE Congdon, JW Wu, N Myeku, YH Figueroa, M Herman, PS Marinec, ...
Autophagy 8 (4), 609-622, 2012
3232012
Features of protein–protein interactions that translate into potent inhibitors: topology, surface area and affinity
MC Smith, JE Gestwicki
Expert reviews in molecular medicine 14, e16, 2012
3062012
Chemical manipulation of hsp70 ATPase activity regulates tau stability
UK Jinwal, Y Miyata, J Koren, JR Jones, JH Trotter, L Chang, J O'Leary, ...
Journal of neuroscience 29 (39), 12079-12088, 2009
2722009
Defining Hsp70 subnetworks in dengue virus replication reveals key vulnerability in flavivirus infection
S Taguwa, K Maringer, X Li, D Bernal-Rubio, JN Rauch, JE Gestwicki, ...
Cell 163 (5), 1108-1123, 2015
2632015
Pharmacological chaperone for α-crystallin partially restores transparency in cataract models
LN Makley, KA McMenimen, BT DeVree, JW Goldman, BN McGlasson, ...
Science 350 (6261), 674-677, 2015
2452015
Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity
JH Bayle, JS Grimley, K Stankunas, JE Gestwicki, TJ Wandless, ...
Chemistry & biology 13 (1), 99-107, 2006
2452006
Harnessing chaperones to generate small-molecule inhibitors of amyloid ß aggregation
JE Gestwicki, GR Crabtree, IA Graef
Science 306 (5697), 865-869, 2004
2452004
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