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Hélène Gleitz
Hélène Gleitz
Assistant Professor, Erasmus MC
Verified email at erasmusmc.nl
Title
Cited by
Cited by
Year
A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency
J Tordo, C O’Leary, ASLM Antunes, N Palomar, P Aldrin-Kirk, M Basche, ...
Brain 141 (7), 2014-2031, 2018
1012018
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis
NB Leimkühler, HFE Gleitz, L Ronghui, IAM Snoeren, SNR Fuchs, ...
Cell Stem Cell 28 (4), 637-652. e8, 2021
1002021
Brain‐targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms
HFE Gleitz, AY Liao, JR Cook, SF Rowlston, GMA Forte, Z D'souza, ...
EMBO molecular medicine 10 (7), e8730, 2018
812018
Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy
RJ Holley, SM Ellison, D Fil, C O’Leary, J McDermott, N Senthivel, ...
Brain 141 (1), 99-116, 2018
732018
Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN
HFE Gleitz, AJF Dugourd, NB Leimkühler, IAM Snoeren, SNR Fuchs, ...
Blood, The Journal of the American Society of Hematology 136 (18), 2051-2064, 2020
712020
Still a burning question: the interplay between inflammation and fibrosis in myeloproliferative neoplasms
HFE Gleitz, A Benabid, RK Schneider
Current Opinion in Hematology 28 (5), 364-371, 2021
452021
Identification of age-dependent motor and neuropsychological behavioural abnormalities in a mouse model of Mucopolysaccharidosis Type II
HFE Gleitz, C O’Leary, RJ Holley, BW Bigger
PLoS One 12 (2), e0172435, 2017
272017
Understanding deregulated cellular and molecular dynamics in the haematopoietic stem cell niche to develop novel therapeutics for bone marrow fibrosis
HFE Gleitz, R Kramann, RK Schneider
The Journal of pathology 245 (2), 138-146, 2018
242018
Biological drivers of clinical phenotype in myelofibrosis
J Mascarenhas, HFE Gleitz, HT Chifotides, CN Harrison, S Verstovsek, ...
Leukemia 37 (2), 255-264, 2023
222023
An improved adeno-associated virus vector for neurological correction of the mouse model of mucopolysaccharidosis IIIA
AL Gray, C O'Leary, A Liao, L Agúndez, AS Youshani, HF Gleitz, H Parker, ...
Human Gene Therapy 30 (9), 1052-1066, 2019
172019
Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion
USA Stalmann, F Ticconi, IAM Snoeren, R Li, HFE Gleitz, GS Cowley, ...
Blood Advances 6 (6), 1780-1796, 2022
72022
Isolation of human bone marrow stromal cells from bone marrow biopsies for single-cell RNA sequencing
HFE Gleitz, IAM Snoeren, SNR Fuchs, NB Leimkühler, RK Schneider
STAR protocols 2 (2), 100538, 2021
32021
Fibrosis driving myofibroblast precursors in MPN and new therapeutic pathways
HFE Gleitz, JE Pritchard, R Kramann, RK Schneider
HemaSphere 3, 142-145, 2019
22019
Fusion of Rabies Virus Glycoprotein or gh625 to Iduronate-2-Sulfatase for the Treatment of Mucopolysaccharidosis Type II
SR Wood, A Chaudrhy, S Ellison, R Searle, C Burgod, G Tehseen, ...
Human Gene Therapy 35 (7-8), 232-242, 2024
12024
S205: INHIBITING THE ALARMIN-DRIVEN HEMATOPOIESIS-STROMAL CELLS CROSSTALK IN PRIMARY MYELOFIBROSIS AMELIORATES BONE MARROW FIBROSIS
H Gleitz, I Snoeren, S Fuchs, J Nagai, A Dugourd, C Boys, V Klöker, ...
HemaSphere 7, e36177f7, 2023
12023
Transcriptional Landscape of the Microenvironment in Bone Marrow Fibrosis at Single Cell Level
NB Leimkühler, R Li, H Gleitz, I Snoeren, S Fuchs, M Crysandt, ...
Blood 134, 1675, 2019
12019
Brain targeted stem cell gene therapy provides long-term correction of mucopolysaccharidosis type II
B Bigger, AY Liao, H Gleitz, R Holley
Molecular Genetics and Metabolism 126 (2), S31-S32, 2019
12019
Whole body correction of severe mucopolysaccharidosis type II by lentiviral-mediated stem cell gene therapy with blood-brain barrier-crossing peptides
HFE Gleitz, C O'Leary, RJ Holley, BW Bigger
Molecular Genetics and Metabolism 1 (120), S56-S57, 2017
12017
Collaborative effect of Csnk1a1 haploinsufficiency and mutant p53 in Myc induction can promote leukemic transformation
SNR Fuchs, USA Stalmann, IAM Snoeren, E Bindels, S Schmitz, ...
Blood Advances 8 (3), 766-779, 2024
2024
Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
JE Pritchard, JE Pearce, IAM Snoeren, SNR Fuchs, K Götz, F Peisker, ...
Cell Reports 43 (1), 2024
2024
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