| Robust deep learning–based protein sequence design using ProteinMPNN J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ... Science 378 (6615), 49-56, 2022 | 518 | 2022 |
| De novo design of protein structure and function with RFdiffusion JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... Nature 620 (7976), 1089-1100, 2023 | 448* | 2023 |
| Scaffolding protein functional sites using deep learning J Wang, S Lisanza, D Juergens, D Tischer, JL Watson, KM Castro, ... Science 377 (6604), 387-394, 2022 | 234 | 2022 |
| De novo design of protein logic gates Z Chen, RD Kibler, A Hunt, F Busch, J Pearl, M Jia, ZL VanAernum, ... Science 368 (6486), 78-84, 2020 | 178 | 2020 |
| Protein sequence design by conformational landscape optimization C Norn, BIM Wicky, D Juergens, S Liu, D Kim, D Tischer, B Koepnick, ... Proceedings of the National Academy of Sciences 118 (11), e2017228118, 2021 | 159* | 2021 |
| Insights into coupled folding and binding mechanisms from kinetic studies SL Shammas, MD Crabtree, L Dahal, BIM Wicky, J Clarke Journal of Biological Chemistry 291 (13), 6689-6695, 2016 | 154 | 2016 |
| Hallucinating symmetric protein assemblies BIM Wicky, LF Milles, A Courbet, RJ Ragotte, J Dauparas, E Kinfu, S Tipps, ... Science 378 (6615), 56-61, 2022 | 120 | 2022 |
| Fast Knoevenagel condensations catalyzed by an artificial Schiff-base-forming enzyme X Garrabou, BIM Wicky, D Hilvert Journal of the American Chemical Society 138 (22), 6972-6974, 2016 | 97 | 2016 |
| Affinity of IDPs to their targets is modulated by ion-specific changes in kinetics and residual structure BIM Wicky, SL Shammas, J Clarke Proceedings of the National Academy of Sciences 114 (37), 9882-9887, 2017 | 87 | 2017 |
| Language models generalize beyond natural proteins R Verkuil, O Kabeli, Y Du, BIM Wicky, LF Milles, J Dauparas, D Baker, ... bioRxiv, 2022.12. 21.521521, 2022 | 50 | 2022 |
| Reconfigurable asymmetric protein assemblies through implicit negative design DD Sahtoe, F Praetorius, A Courbet, Y Hsia, BIM Wicky, NI Edman, ... Science 375 (6578), eabj7662, 2022 | 43 | 2022 |
| Stereodivergent evolution of artificial enzymes for the michael reaction X Garrabou, DS Macdonald, BIM Wicky, D Hilvert Angewandte Chemie 130 (19), 5386-5389, 2018 | 42 | 2018 |
| Extrinsic conditions influence the self-association and structure of IF1, the regulatory protein of mitochondrial ATP synthase V Boreikaite, BIM Wicky, IN Watt, J Clarke, JE Walker Proceedings of the National Academy of Sciences 116 (21), 10354-10359, 2019 | 30 | 2019 |
| TAL effectors specificity stems from negative discrimination BIM Wicky, M Stenta, M Dal Peraro PLoS One 8 (11), e80261, 2013 | 26 | 2013 |
| Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants JZ Zhang, HW Yeh, AC Walls, BIM Wicky, KR Sprouse, LA VanBlargan, ... Nature biotechnology 40 (9), 1336-1340, 2022 | 22 | 2022 |
| Improving protein expression, stability, and function with ProteinMPNN KH Sumida, R Núñez-Franco, I Kalvet, SJ Pellock, BIM Wicky, LF Milles, ... Journal of the American Chemical Society 146 (3), 2054-2061, 2024 | 15 | 2024 |
| Functional dissection of intersubunit interactions in the EspR virulence regulator of Mycobacterium tuberculosis B Blasco, A Japaridze, M Stenta, BIM Wicky, G Dietler, M Dal Peraro, ... Journal of bacteriology 196 (10), 1889-1900, 2014 | 15 | 2014 |
| Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐xL and MCL‐1 through Noncanonical Structural Motifs** JA Miles, F Hobor, CH Trinh, J Taylor, C Tiede, PR Rowell, BR Jackson, ... ChemBioChem 22 (1), 232-240, 2021 | 11 | 2021 |
| Stepwise design of pseudosymmetric protein hetero-oligomers RD Kibler, S Lee, MA Kennedy, BIM Wicky, SM Lai, MM Kostelic, X Li, ... bioRxiv, 2023 | 6 | 2023 |
| Improving protein expression, stability, and function with ProteinMPNN KH Sumida, R Núñez Franco, I Kalvet, SJ Pellock, BIM Wicky, LF Milles, ... bioRxiv, 2023.10. 03.560713, 2023 | 6 | 2023 |
David BakerUniversity of WashingtonVerified email at uw.edu
