Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence G Hewitt, D Jurk, FDM Marques, C Correia-Melo, T Hardy, A Gackowska, ... Nature communications 3 (1), 708, 2012 | 877 | 2012 |
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ... Nature communications 5 (1), 4172, 2014 | 768 | 2014 |
Mitochondria are required for pro‐ageing features of the senescent phenotype C Correia‐Melo, FDM Marques, R Anderson, G Hewitt, R Hewitt, J Cole, ... The EMBO journal 35 (7), 724-742, 2016 | 630 | 2016 |
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... The EMBO journal 38 (5), e100492, 2019 | 376 | 2019 |
Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence? C Correia-Melo, G Hewitt, JF Passos Longevity & healthspan 3, 1-9, 2014 | 191 | 2014 |
Mitochondria: are they causal players in cellular senescence? C Correia-Melo, JF Passos Biochimica et Biophysica Acta (BBA)-Bioenergetics 1847 (11), 1373-1379, 2015 | 180 | 2015 |
DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease J Birch, RK Anderson, C Correia-Melo, D Jurk, G Hewitt, FM Marques, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 309 …, 2015 | 162 | 2015 |
SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair G Hewitt, B Carroll, R Sarallah, C Correia-Melo, M Ogrodnik, G Nelson, ... Autophagy 12 (10), 1917-1930, 2016 | 145 | 2016 |
A time-resolved proteomic and prognostic map of COVID-19 V Demichev, P Tober-Lau, O Lemke, T Nazarenko, C Thibeault, ... Cell systems 12 (8), 780-794. e7, 2021 | 143 | 2021 |
CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore‐microtubule dynamics to promote mitotic progression and fidelity AL Manning, SF Bakhoum, S Maffini, C Correia‐Melo, H Maiato, ... The EMBO journal 29 (20), 3531-3543, 2010 | 140 | 2010 |
Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism V Olin-Sandoval, JSL Yu, L Miller-Fleming, MT Alam, S Kamrad, ... Nature 572 (7768), 249-253, 2019 | 116 | 2019 |
Rapamycin improves healthspan but not inflammaging in nfκb1−/− mice C Correia‐Melo, J Birch, E Fielder, D Rahmatika, J Taylor, J Chapman, ... Aging cell 18 (1), e12882, 2019 | 68 | 2019 |
Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance JSL Yu, C Correia-Melo, F Zorrilla, L Herrera-Dominguez, MY Wu, J Hartl, ... Nature Microbiology, 1-14, 2022 | 60 | 2022 |
Depletion of mitochondria in mammalian cells through enforced mitophagy C Correia-Melo, G Ichim, SWG Tait, JF Passos nature protocols 12 (1), 183-194, 2017 | 52 | 2017 |
A proteomic survival predictor for COVID-19 patients in intensive care V Demichev, P Tober-Lau, T Nazarenko, O Lemke, S Kaur Aulakh, ... PLOS Digital Health 1 (1), e0000007, 2022 | 40 | 2022 |
Pyphe, a python toolbox for assessing microbial growth and cell viability in high-throughput colony screens S Kamrad, M Rodríguez-López, C Cotobal, C Correia-Melo, M Ralser, ... Elife 9, e55160, 2020 | 39 | 2020 |
Biochemical principles enabling metabolic cooperativity and phenotypic heterogeneity at the single cell level K Campbell, L Herrera-Dominguez, C Correia-Melo, A Zelezniak, ... Current Opinion in Systems Biology 8, 97-108, 2018 | 32 | 2018 |
Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan C Correia-Melo, S Kamrad, R Tengölics, CB Messner, P Trebulle, ... Cell 186 (1), 63-79. e21, 2023 | 27 | 2023 |
Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance S Kamrad, J Grossbach, M Rodríguez‐López, M Mülleder, SJ Townsend, ... Molecular systems biology 16 (4), e9270, 2020 | 26 | 2020 |
Robust multiparametric assessment of cellular senescence C Correia-Melo, D Jurk, JF Passos Cell Senescence: Methods and Protocols, 409-419, 2013 | 21 | 2013 |