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Gregory L. Dignon
Gregory L. Dignon
Assistant Professor of Chemical Engineering - Rutgers University
Verified email at rutgers.edu - Homepage
Title
Cited by
Cited by
Year
Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity
Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ...
The EMBO journal 36 (20), 2951-2967, 2017
5842017
Molecular interactions underlying liquid− liquid phase separation of the FUS low-complexity domain
AC Murthy, GL Dignon, Y Kan, GH Zerze, SH Parekh, J Mittal, NL Fawzi
Nature structural & molecular biology 26 (7), 637-648, 2019
4842019
Sequence determinants of protein phase behavior from a coarse-grained model
GL Dignon, W Zheng, YC Kim, RB Best, J Mittal
PLoS computational biology 14 (1), e1005941, 2018
4162018
Biomolecular phase separation: from molecular driving forces to macroscopic properties
GL Dignon, RB Best, J Mittal
Annual review of physical chemistry 71, 53-75, 2020
3802020
Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation
VH Ryan, GL Dignon, GH Zerze, CV Chabata, R Silva, AE Conicella, ...
Molecular cell 69 (3), 465-479. e7, 2018
3382018
Relation between single-molecule properties and phase behavior of intrinsically disordered proteins
GL Dignon, W Zheng, RB Best, YC Kim, J Mittal
Proceedings of the National Academy of Sciences 115 (40), 9929-9934, 2018
2712018
TDP-43 á-helical structure tunes liquid–liquid phase separation and function
AE Conicella, GL Dignon, GH Zerze, HB Schmidt, AM D¢Ordine, YC Kim, ...
Proceedings of the National Academy of Sciences 117 (11), 5883-5894, 2020
2682020
Temperature-controlled liquid–liquid phase separation of disordered proteins
GL Dignon, W Zheng, YC Kim, J Mittal
ACS central science 5 (5), 821-830, 2019
2072019
Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior
BS Schuster, GL Dignon, WS Tang, FM Kelley, AK Ranganath, ...
Proceedings of the National Academy of Sciences 117 (21), 11421-11431, 2020
1972020
Molecular details of protein condensates probed by microsecond long atomistic simulations
W Zheng, GL Dignon, N Jovic, X Xu, RM Regy, NL Fawzi, YC Kim, ...
The Journal of Physical Chemistry B 124 (51), 11671-11679, 2020
1212020
Simulation methods for liquid–liquid phase separation of disordered proteins
GL Dignon, W Zheng, J Mittal
Current opinion in chemical engineering 23, 92-98, 2019
952019
Sequence dependent phase separation of protein-polynucleotide mixtures elucidated using molecular simulations
RM Regy, GL Dignon, W Zheng, YC Kim, J Mittal
Nucleic acids research 48 (22), 12593-12603, 2020
722020
Hydropathy patterning complements charge patterning to describe conformational preferences of disordered proteins
W Zheng, G Dignon, M Brown, YC Kim, J Mittal
The journal of physical chemistry letters 11 (9), 3408-3415, 2020
692020
The protein folding problem: The role of theory
R Nassar, GL Dignon, RM Razban, KA Dill
Journal of molecular biology 433 (20), 167126, 2021
632021
A predictive coarse-grained model for position-specific effects of post-translational modifications
TM Perdikari, N Jovic, GL Dignon, YC Kim, NL Fawzi, J Mittal
Biophysical Journal 120 (7), 1187-1197, 2021
552021
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration
VH Ryan, TM Perdikari, MT Naik, CF Saueressig, J Lins, GL Dignon, ...
The EMBO Journal 40 (3), e105001, 2021
472021
Interplay between membrane composition and structural stability of membrane-bound hIAPP
GL Dignon, GH Zerze, J Mittal
The Journal of Physical Chemistry B 121 (37), 8661-8668, 2017
282017
Accelerating Protein Folding Molecular Dynamics Using Inter-Residue Distances from Machine Learning Servers
R Nassar, E Brini, S Parui, C Liu, GL Dignon, KA Dill
Journal of Chemical Theory and Computation 18 (3), 1929-1935, 2022
102022
A High-Throughput Approach to Phase Separation of Disordered Proteins
GL Dignon, W Zheng, Y Kim, J Mittal
Biophysical Journal 116 (3), 350a, 2019
22019
Alpha-Helical Structure in TDP-43 Tunes Liquid-liquid Phase Separation and Cellular Function
AE Conicella, G Dignon, GH Zerze, B Schmidt, MD Alexandra, Y Kim, ...
Biophysical Journal 118 (3), 5a-6a, 2020
12020
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