| Gain of function of mutant p53 by coaggregation with multiple tumor suppressors J Xu, J Reumers, JR Couceiro, F De Smet, R Gallardo, S Rudyak, ... Nature chemical biology 7 (5), 285-295, 2011 | 565 | 2011 |
| Alzheimer’s-causing mutations shift Aβ length by destabilizing γ-secretase-Aβn interactions M Szaruga, B Munteanu, S Lismont, S Veugelen, K Horré, M Mercken, ... Cell 170 (3), 443-456. e14, 2017 | 231 | 2017 |
| The Alzheimer disease protective mutation A2T modulates kinetic and thermodynamic properties of amyloid-β (Aβ) aggregation I Benilova, R Gallardo, AA Ungureanu, VC Cano, A Snellinx, M Ramakers, ... Journal of Biological Chemistry 289 (45), 30977-30989, 2014 | 179 | 2014 |
| Amyloid structures: much more than just a cross-β fold R Gallardo, NA Ranson, SE Radford Current opinion in structural biology 60, 7-16, 2020 | 174 | 2020 |
| Proteostasis of islet amyloid polypeptide: a molecular perspective of risk factors and protective strategies for type II diabetes D Milardi, E Gazit, SE Radford, Y Xu, RU Gallardo, A Caflisch, ... Chemical Reviews 121 (3), 1845-1893, 2021 | 146 | 2021 |
| Prediction and reduction of the aggregation of monoclonal antibodies R van der Kant, AR Karow-Zwick, J Van Durme, M Blech, R Gallardo, ... Journal of molecular biology 429 (8), 1244-1261, 2017 | 145 | 2017 |
| Accurate prediction of DnaK-peptide binding via homology modelling and experimental data J Van Durme, S Maurer-Stroh, R Gallardo, H Wilkinson, F Rousseau, ... PLoS computational biology 5 (8), e1000475, 2009 | 143 | 2009 |
| Hsp90 mediates membrane deformation and exosome release E Lauwers, YC Wang, R Gallardo, R Van der Kant, E Michiels, J Swerts, ... Molecular cell 71 (5), 689-702. e9, 2018 | 136 | 2018 |
| Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy L Almeida-Souza, S Goethals, V De Winter, I Dierick, R Gallardo, ... Journal of biological chemistry 285 (17), 12778-12786, 2010 | 121 | 2010 |
| Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly R Gallardo, MG Iadanza, Y Xu, GR Heath, R Foster, SE Radford, ... Nature Structural & Molecular Biology 27 (11), 1048-1056, 2020 | 73 | 2020 |
| WALTZ-DB: a benchmark database of amyloidogenic hexapeptides J Beerten, J Van Durme, R Gallardo, E Capriotti, L Serpell, F Rousseau, ... Bioinformatics 31 (10), 1698-1700, 2015 | 72 | 2015 |
| Structure of the extracellular domain of matrix protein 2 of influenza A virus in complex with a protective monoclonal antibody KJ Cho, B Schepens, JH Seok, S Kim, K Roose, JH Lee, R Gallardo, ... Journal of virology 89 (7), 3700-3711, 2015 | 72 | 2015 |
| De novo design of a biologically active amyloid R Gallardo, M Ramakers, F De Smet, F Claes, L Khodaparast, ... Science 354 (6313), aah4949, 2016 | 71 | 2016 |
| Solubis: a webserver to reduce protein aggregation through mutation J Van Durme, G De Baets, R Van Der Kant, M Ramakers, A Ganesan, ... Protein Engineering, Design and Selection 29 (8), 285-289, 2016 | 67 | 2016 |
| A homologue of the Parkinson’s disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover E Deyaert, L Wauters, G Guaitoli, A Konijnenberg, M Leemans, ... Nature communications 8 (1), 1008, 2017 | 64 | 2017 |
| Structural diversity of PDZ–lipid interactions R Gallardo, Y Ivarsson, J Schymkowitz, F Rousseau, P Zimmermann Chembiochem 11 (4), 456-467, 2010 | 63 | 2010 |
| Structural hot spots for the solubility of globular proteins A Ganesan, A Siekierska, J Beerten, M Brams, J Van Durme, G De Baets, ... Nature communications 7 (1), 10816, 2016 | 62 | 2016 |
| Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis L Khodaparast, L Khodaparast, R Gallardo, NN Louros, E Michiels, ... Nature communications 9 (1), 866, 2018 | 59 | 2018 |
| Protein aggregation as an antibiotic design strategy NG Bednarska, J Van Eldere, R Gallardo, A Ganesan, M Ramakers, ... Molecular microbiology 99 (5), 849-865, 2016 | 52 | 2016 |
| Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling AL Egea-Jimenez, R Gallardo, A Garcia-Pino, Y Ivarsson, AM Wawrzyniak, ... Nature Communications 7 (1), 12101, 2016 | 42 | 2016 |
