Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion T Fujino, H Asaba, MJ Kang, Y Ikeda, H Sone, S Takada, DH Kim, RX Ioka, ... Proceedings of the National Academy of Sciences 100 (1), 229-234, 2003 | 473 | 2003 |
Immunogenetic and clinical characterization of slowly progressive IDDM T Kobayashi, K Tamemoto, K Nakanishi, N Kato, M Okubo, H Kajio, ... Diabetes care 16 (5), 780-788, 1993 | 354 | 1993 |
Corticosteroid-responsive diabetes mellitus associated with autoimmune pancreatitis S Tanaka, T Kobayashi, K Nakanishi, M Okubo, T Murase, M Hashimoto, ... The Lancet 356 (9233), 910-911, 2000 | 198 | 2000 |
In situ characterization of islets in diabetes with a mitochondrial DNA mutation at nucleotide position 3243 T Kobayashi, K Nakanishi, H Nakase, H Kajio, M Okubo, T Murase, ... Diabetes 46 (10), 1567-1571, 1997 | 102 | 1997 |
Prospective study of lipoprotein (a) as a risk factor for atherosclerotic cardiovascular disease in patients with diabetes T Hiraga, T Kobayashi, M Okubo, K Nakanishi, T Sugimoto, Y Ohashi, ... Diabetes Care 18 (2), 241-244, 1995 | 102 | 1995 |
Impact of sodium glucose cotransporter 2 inhibitor on histological features and glucose metabolism of non‐alcoholic fatty liver disease complicated by diabetes mellitus N Akuta, Y Kawamura, C Watanabe, A Nishimura, M Okubo, Y Mori, ... Hepatology Research 49 (5), 531-539, 2019 | 97 | 2019 |
Association of HLA-DQ genotype in autoantibody-negative and rapid-onset type 1 diabetes S Tanaka, T Kobayashi, K Nakanishi, R Koyama, M Okubo, T Murase, ... Diabetes care 25 (12), 2302-2307, 2002 | 95 | 2002 |
Evidence of primary β-cell destruction by T-cells and β-cell differentiation from pancreatic ductal cells in diabetes associated with active autoimmune chronic pancreatitis S Tanaka, T Kobayashi, K Nakanishi, M Okubo, T Murase, M Hashimoto, ... Diabetes Care 24 (9), 1661-1667, 2001 | 75 | 2001 |
Exocrine pancreatic ductograms in insulin-dependent diabetes mellitus. K Nakanishi, T Kobayashi, H Miyashita, M Okubo, T Sugimoto, T Murase, ... American Journal of Gastroenterology (Springer Nature) 89 (5), 1994 | 75 | 1994 |
Unique epitopes of glutamic acid decarboxylase autoantibodies in slowly progressive type 1 diabetes T Kobayashi, S Tanaka, M Okubo, K Nakanishi, T Murase, A Lernmark The Journal of Clinical Endocrinology & Metabolism 88 (10), 4768-4775, 2003 | 73 | 2003 |
Molecular analysis of the AGL gene: heterogeneity of mutations in patients with glycogen storage disease type III from Germany, Canada, Afghanistan, Iran, and Turkey Y Endo, A Horinishi, M Vorgerd, Y Aoyama, T Ebara, T Murase, ... Journal of human genetics 51 (11), 958-963, 2006 | 70 | 2006 |
Lipoprotein (a)-cholesterol: a significant component of serum cholesterol K Kinpara, H Okada, A Yoneyama, M Okubo, T Murase Clinica chimica acta 412 (19-20), 1783-1787, 2011 | 67 | 2011 |
Clonal chromosomal aberrations accompanied by strong telomerase activity in immortalization of human B-lymphoblastoid cell lines transformed by Epstein-Barr virus M Okubo, Y Tsurukubo, T Higaki, T Kawabe, M Goto, T Murase, T Ide, ... Cancer genetics and Cytogenetics 129 (1), 30-34, 2001 | 64 | 2001 |
GAD antibodies seldom disappear in slowly progressive IDDM K Tetsuro, K Nakanishi, M Okubo, T Murase, K Kosaka Diabetes Care 19 (9), 1031-1031, 1996 | 63 | 1996 |
Relationships among residual β cells, exocrine pancreas, and islet cell antibodies in insulin-dependent diabetes mellitus K Nakanishi, T Kobayashi, H Miyashita, M Okubo, T Sugimoto, T Murase, ... Metabolism 42 (2), 196-203, 1993 | 63 | 1993 |
A novel complex deletion–insertion mutation mediated by Alu repetitive elements leads to lipoprotein lipase deficiency M Okubo, A Horinishi, M Saito, T Ebara, Y Endo, K Kaku, T Murase, M Eto Molecular genetics and metabolism 92 (3), 229-233, 2007 | 54 | 2007 |
Seven novel sequence variants in the human low density lipoprotein receptor related protein 5 (LRP5) gene M Okubo, A Horinishi, DH Kim, TT Yamamoto, T Murase Human mutation 19 (2), 186-186, 2002 | 49 | 2002 |
Heterogeneous mutations in the glycogen-debranching enzyme gene are responsible for glycogen storage disease type IIIa in Japan M Okubo, A Horinishi, M Takeuchi, Y Suzuki, N Sakura, Y Hasegawa, ... Human genetics 106, 108-115, 2000 | 49 | 2000 |
Efficacy and safety in sitagliptin therapy for diabetes complicated by non‐alcoholic fatty liver disease Y Arase, Y Kawamura, Y Seko, M Kobayashi, F Suzuki, Y Suzuki, N Akuta, ... Hepatology Research 43 (11), 1163-1168, 2013 | 45 | 2013 |
Distinct mutations in the glycogen debranching enzyme found in glycogen storage disease type III lead to impairment in diverse cellular functions A Cheng, M Zhang, M Okubo, K Omichi, AR Saltiel Human molecular genetics 18 (11), 2045-2052, 2009 | 44 | 2009 |