An efficient platform for astrocyte differentiation from human induced pluripotent stem cells TCW Julia, M Wang, AA Pimenova, KR Bowles, BJ Hartley, E Lacin, ... Stem cell reports 9 (2), 600-614, 2017 | 363 | 2017 |
High-content screening in hPSC-neural progenitors identifies drug candidates that inhibit Zika virus infection in fetal-like organoids and adult brain T Zhou, L Tan, GY Cederquist, Y Fan, BJ Hartley, S Mukherjee, ... Cell stem cell 21 (2), 274-283. e5, 2017 | 236 | 2017 |
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells SM Ho, BJ Hartley, TCW Julia, M Beaumont, K Stafford, PA Slesinger, ... Methods 101, 113-124, 2016 | 155 | 2016 |
Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains GE Hoffman, BJ Hartley, E Flaherty, I Ladran, P Gochman, DM Ruderfer, ... Nature communications 8 (1), 2225, 2017 | 146 | 2017 |
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain Y Jiang, YHE Loh, P Rajarajan, T Hirayama, W Liao, BS Kassim, ... Nature genetics 49 (8), 1239-1250, 2017 | 146 | 2017 |
Dysregulation of miRNA-9 in a subset of schizophrenia patient-derived neural progenitor cells A Topol, S Zhu, BJ Hartley, J English, ME Hauberg, N Tran, ... Cell reports 15 (5), 1024-1036, 2016 | 132 | 2016 |
Sex-specific role for the long non-coding RNA LINC00473 in depression O Issler, YY van der Zee, A Ramakrishnan, J Wang, C Tan, YHE Loh, ... Neuron 106 (6), 912-926. e5, 2020 | 109 | 2020 |
A psychiatric disease-related circular RNA controls synaptic gene expression and cognition AJ Zimmerman, AK Hafez, SK Amoah, BA Rodriguez, M Dell’Orco, ... Molecular psychiatry 25 (11), 2712-2727, 2020 | 106 | 2020 |
In utero exposure to maternal smoking is associated with DNA methylation alterations and reduced neuronal content in the developing fetal brain Z Chatterton, BJ Hartley, MH Seok, N Mendelev, S Chen, M Milekic, ... Epigenetics & chromatin 10, 1-11, 2017 | 98 | 2017 |
Evaluating synthetic activation and repression of neuropsychiatric-related genes in hiPSC-derived NPCs, neurons, and astrocytes SM Ho, BJ Hartley, E Flaherty, P Rajarajan, R Abdelaal, I Obiorah, ... Stem cell reports 9 (2), 615-628, 2017 | 77 | 2017 |
Expression-based drug screening of neural progenitor cells from individuals with schizophrenia B Readhead, BJ Hartley, BJ Eastwood, DA Collier, D Evans, R Farias, ... Nature communications 9 (1), 4412, 2018 | 76 | 2018 |
Increased abundance of translation machinery in stem cell–derived neural progenitor cells from four schizophrenia patients A Topol, JA English, E Flaherty, P Rajarajan, BJ Hartley, S Gupta, ... Translational psychiatry 5 (10), e662-e662, 2015 | 72 | 2015 |
Characterization of molecular and cellular phenotypes associated with a heterozygous CNTNAP2 deletion using patient-derived hiPSC neural cells IS Lee, C Carvalho, P Douvaras, SM Ho, BJ Hartley, LW Zuccherato, ... NPJ schizophrenia 1 (1), 1-5, 2015 | 60 | 2015 |
Neural organoids for disease phenotyping, drug screening and developmental biology studies BJ Hartley, KJ Brennand Neurochemistry international 106, 85-93, 2017 | 47 | 2017 |
Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models J Xu, BJ Hartley, P Kurup, A Phillips, A Topol, M Xu, C Ononenyi, ... Molecular psychiatry 23 (2), 271-281, 2018 | 41 | 2018 |
Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells CM Nefzger, CT Su, SA Fabb, BJ Hartley, SJ Beh, WR Zeng, JM Haynes, ... Stem Cells 30 (7), 1349-1361, 2012 | 36 | 2012 |
Dopaminergic differentiation of schizophrenia hiPSCs BJ Hartley, N Tran, I Ladran, K Reggio, KJ Brennand Molecular psychiatry 20 (5), 549-550, 2015 | 33 | 2015 |
Resolving the unconventional mechanisms underlying RXFP1 and RXFP2 receptor function BJ Hartley, DJ Scott, GE Callander, TN Wilkinson, DE Ganella, CK Kong, ... Annals of the New York Academy of Sciences 1160 (1), 67-73, 2009 | 30 | 2009 |
A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning AK Hafez, AJ Zimmerman, G Papageorgiou, J Chandrasekaran, ... Cell reports 38 (3), 2022 | 23 | 2022 |
Human pluripotent stem cell derived midbrain PITX3eGFP/w neurons: a versatile tool for pharmacological screening and neurodegenerative modeling B Watmuff, BJ Hartley, CPJ Hunt, SA Fabb, CW Pouton, JM Haynes Frontiers in cellular neuroscience 9, 104, 2015 | 23 | 2015 |