Ellen van Rooijen
Ellen van Rooijen
Postdoctoral Researcher, Boston Children's Hospital, Harvard Medical School, Harvard Stem Cell and
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα enders.tch.harvard.edu - Αρχική σελίδα
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Genetic analysis of von Hippel‐Lindau disease
M Nordstrom‐O'Brien, RB van der Luijt, E van Rooijen, ...
Human mutation 31 (5), 521-537, 2010
2742010
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation
CK Kaufman, C Mosimann, ZP Fan, S Yang, AJ Thomas, J Ablain, JL Tan, ...
Science 351 (6272), 2016
2522016
Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia
E van Rooijen, EE Voest, I Logister, J Korving, T Schwerte, ...
Blood, The Journal of the American Society of Hematology 113 (25), 6449-6460, 2009
1162009
von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish
E van Rooijen, EE Voest, I Logister, J Bussmann, J Korving, FJ van Eeden, ...
Disease models & mechanisms 3 (5-6), 343-353, 2010
962010
A quantitative system for studying metastasis using transparent zebrafish
S Heilmann, K Ratnakumar, EM Langdon, ER Kansler, IS Kim, ...
Cancer research 75 (20), 4272-4282, 2015
932015
LRRC50, a conserved ciliary protein implicated in polycystic kidney disease
E van Rooijen, RH Giles, EE Voest, C van Rooijen, S Schulte-Merker, ...
Journal of the American Society of Nephrology 19 (6), 1128-1138, 2008
832008
Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
Y Yu, K Schleich, B Yue, S Ji, P Lohneis, K Kemper, MS Silvis, N Qutob, ...
Cancer Cell, 2018
792018
The zebrafish mutants dre, uki, and lep encode negative regulators of the hedgehog signaling pathway
MJ Koudijs, MJ Den Broeder, A Keijser, E Wienholds, S Houwing, ...
PLoS Genet 1 (2), e19, 2005
772005
A zebrafish model to study and therapeutically manipulate hypoxia signaling in tumorigenesis
K Santhakumar, EC Judson, PM Elks, S McKee, S Elworthy, ...
Cancer research 72 (16), 4017-4027, 2012
642012
The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish
YU van der Velden, L Wang, J Zevenhoven, E van Rooijen, ...
Proceedings of the National Academy of Sciences 108 (11), 4358-4363, 2011
592011
Stress from nucleotide depletion activates the transcriptional regulator HEXIM1 to suppress melanoma
JL Tan, RD Fogley, RA Flynn, J Ablain, S Yang, V Saint-André, ZP Fan, ...
Molecular cell 62 (1), 34-46, 2016
542016
Mutations in LRRC50 predispose zebrafish and humans to seminomas
SG Basten, EE Davis, AJM Gillis, E van Rooijen, H Stoop, N Babala, ...
PLoS Genet 9 (4), e1003384, 2013
462013
EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay
S Volpi, Y Yamazaki, PM Brauer, E van Rooijen, A Hayashida, ...
Journal of Experimental Medicine, 2017
442017
From fish bowl to bedside: The power of zebrafish to unravel melanoma pathogenesis and discover new therapeutics
E van Rooijen, M Fazio, L Zon
Pigment Cell & Melanoma Research, 2017
362017
Pharmacological HIF2α inhibition improves VHL disease–associated phenotypes in zebrafish model
AM Metelo, HR Noonan, X Li, Y Jin, R Baker, L Kamentsky, Y Zhang, ...
The Journal of clinical investigation 125 (5), 1987-1997, 2015
352015
Zebrafish as an innovative model for neuroendocrine tumors
G Vitale, G Gaudenzi, A Dicitore, F Cotelli, D Ferone, L Persani
Endocrine-Related Cancer 21 (1), R67-R83, 2014
292014
Balancing the optimal and the feasible: a practical guide for setting up patient registries for the collection of real-world data for health care decision making based on Dutch …
S de Groot, N van der Linden, MG Franken, HM Blommestein, ...
Value in Health 20 (4), 627-636, 2017
262017
A zebrafish model for VHL and hypoxia signaling
E van Rooijen, K Santhakumar, I Logister, E Voest, S Schulte-Merker, ...
Methods in cell biology 105, 163-190, 2011
242011
Regulation of E2F1 by the von Hippel–Lindau tumour suppressor protein predicts survival in renal cell cancer patients
DA Mans, JS Vermaat, BG Weijts, E Van Rooijen, J Van Reeuwijk, K Boldt, ...
The Journal of pathology 231 (1), 117-129, 2013
222013
Growth inhibition of lung cancer cells by adenosine 5-triphosphate
HJ Agteresch, MHC van Rooijen, JWO van den Berg, GJ Minderman, ...
Drug Development Research 60 (3), 196-203, 2003
182003
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