| Ceramide in apoptosis: an overview and current perspectives BJ Pettus, CE Chalfant, YA Hannun Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2002 | 969 | 2002 |
| Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling CE Chalfant, S Spiegel Journal of cell science 118 (20), 4605-4612, 2005 | 535 | 2005 |
| Ceramide 1-phosphate is a direct activator of cytosolic phospholipase A2 BJ Pettus, A Bielawska, P Subramanian, DS Wijesinghe, M Maceyka, ... Journal of Biological Chemistry 279 (12), 11320-11326, 2004 | 416 | 2004 |
| De Novo Ceramide Regulates the Alternative Splicing of Caspase 9 and Bcl-x in A549 Lung Adenocarcinoma Cells: DEPENDENCE ON PROTEIN PHOSPHATASE-1∗ CE Chalfant, K Rathman, RL Pinkerman, RE Wood, LM Obeid, ... Journal of Biological Chemistry 277 (15), 12587-12595, 2002 | 409 | 2002 |
| The sphingosine kinase 1/sphingosine‐1‐phosphate pathway mediates COX‐2 induction and PGE2 production in response to TNF‐á BJ Pettus, J Bielawski, AM Porcelli, DL Reames, KR Johnson, J Morrow, ... The FASEB Journal 17 (11), 1411-1421, 2003 | 406 | 2003 |
| Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A: activation is stereospecific and regulated by phosphatidic acid CE Chalfant, K Kishikawa, MC Mumby, C Kamibayashi, A Bielawska, ... Journal of Biological Chemistry 274 (29), 20313-20317, 1999 | 373 | 1999 |
| The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x MP Paronetto, T Achsel, A Massiello, CE Chalfant, C Sette The Journal of cell biology 176 (7), 929-939, 2007 | 370 | 2007 |
| Ceramide kinase mediates cytokine-and calcium ionophore-induced arachidonic acid release BJ Pettus, A Bielawska, S Spiegel, P Roddy, YA Hannun, CE Chalfant Journal of Biological Chemistry 278 (40), 38206-38213, 2003 | 252 | 2003 |
| Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids DK Simanshu, RK Kamlekar, DS Wijesinghe, X Zou, X Zhai, SK Mishra, ... Nature 500 (7463), 463-467, 2013 | 199 | 2013 |
| Mechanism of apoptosis induced by the inhibition of fatty acid synthase in breast cancer cells S Bandyopadhyay, R Zhan, Y Wang, SK Pai, S Hirota, S Hosobe, ... Cancer research 66 (11), 5934-5940, 2006 | 198 | 2006 |
| FAS activation induces dephosphorylation of SR proteins: dependence on the de novo generation of ceramide and activation of protein phosphatase 1 CE Chalfant, B Ogretmen, S Galadari, BJ Kroesen, BJ Pettus, YA Hannun Journal of Biological Chemistry 276 (48), 44848-44855, 2001 | 197 | 2001 |
| The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors SG Payne, CA Oskeritzian, R Griffiths, P Subramanian, SE Barbour, ... Blood 109 (3), 1077-1085, 2007 | 193 | 2007 |
| Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension J Gomez-Arroyo, S Mizuno, K Szczepanek, B Van Tassell, R Natarajan, ... Circulation: Heart Failure 6 (1), 136-144, 2013 | 192 | 2013 |
| The structural requirements for ceramide activation of serine-threonine protein phosphatases CE Chalfant, Z Szulc, P Roddy, A Bielawska, YA Hannun Journal of lipid research 45 (3), 496-506, 2004 | 186 | 2004 |
| Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide LJA Spijkers, RFP van den Akker, BJA Janssen, JJ Debets, JGR De Mey, ... PloS one 6 (7), e21817, 2011 | 182 | 2011 |
| The coordination of prostaglandin E2 production by sphingosine-1-phosphate and ceramide-1-phosphate BJ Pettus, K Kitatani, CE Chalfant, TA Taha, T Kawamori, J Bielawski, ... Molecular pharmacology 68 (2), 330-335, 2005 | 169 | 2005 |
| Sphingolipids in inflammation: roles and implications BJ Pettus, CE Chalfant, YA Hannun Current molecular medicine 4 (4), 405-418, 2004 | 154 | 2004 |
| Ceramide-1-phosphate binds group IVA cytosolic phospholipase a2 via a novel site in the C2 domain RV Stahelin, P Subramanian, M Vora, W Cho, CE Chalfant Journal of Biological Chemistry 282 (28), 20467-20474, 2007 | 153 | 2007 |
| Ceramide 1-phosphate acts as a positive allosteric activator of group IVA cytosolic phospholipase A2á and enhances the interaction of the enzyme with phosphatidylcholine P Subramanian, RV Stahelin, Z Szulc, A Bielawska, W Cho, CE Chalfant Journal of Biological Chemistry 280 (18), 17601-17607, 2005 | 151 | 2005 |
| Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a JC Shultz, RW Goehe, DS Wijesinghe, C Murudkar, AJ Hawkins, JW Shay, ... Cancer research 70 (22), 9185-9196, 2010 | 144 | 2010 |
