Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug LS Conklin, JM Damsker, EP Hoffman, WJ Jusko, PD Mavroudis, ... Pharmacological Research 136, 140-150, 2018 | 93 | 2018 |
Entrainment of peripheral clock genes by cortisol PD Mavroudis, JD Scheff, SE Calvano, SF Lowry, IP Androulakis Physiological genomics 44 (11), 607-621, 2012 | 80 | 2012 |
Systems biology of circadian-immune interactions PD Mavroudis, JD Scheff, SE Calvano, IP Androulakis Journal of innate immunity 5 (2), 153-162, 2013 | 64 | 2013 |
Modeling autonomic regulation of cardiac function and heart rate variability in human endotoxemia JD Scheff, PD Mavroudis, SE Calvano, SF Lowry, IP Androulakis Physiological genomics 43 (16), 951-964, 2011 | 61 | 2011 |
Circadian characteristics of permissive and suppressive effects of cortisol and their role in homeostasis and the acute inflammatory response PD Mavroudis, SA Corbett, SE Calvano, IP Androulakis Mathematical biosciences 260, 54-64, 2015 | 45 | 2015 |
Mathematical modeling of light-mediated HPA axis activity and downstream implications on the entrainment of peripheral clock genes PD Mavroudis, SA Corbett, SE Calvano, IP Androulakis Physiological genomics 46 (20), 766-778, 2014 | 45 | 2014 |
Daily variation of gene expression in diverse rat tissues PD Mavroudis, DC DuBois, RR Almon, WJ Jusko PloS one 13 (5), e0197258, 2018 | 38 | 2018 |
Machine learning guided early drug discovery of small molecules N Pillai, A Dasgupta, S Sudsakorn, J Fretland, PD Mavroudis Drug Discovery Today 27 (8), 2209-2215, 2022 | 28 | 2022 |
Development and validation of a physiology-based model for the prediction of pharmacokinetics/toxicokinetics in rabbits PD Mavroudis, HE Hermes, D Teutonico, TG Preuss, S Schneckener PloS one 13 (3), e0194294, 2018 | 24 | 2018 |
Translational applications of evaluating physiologic variability in human endotoxemia JD Scheff, PD Mavroudis, SE Calvano, IP Androulakis Journal of clinical monitoring and computing 27, 405-415, 2013 | 23 | 2013 |
Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat PD Mavroudis, DC DuBois, RR Almon, WJ Jusko PLoS One 13 (6), e0197534, 2018 | 22 | 2018 |
Modeling physiologic variability in human endotoxemia JD Scheff, PD Mavroudis, PT Foteinou, SE Calvano, I Androulakis Critical Reviews™ in Biomedical Engineering 40 (4), 2012 | 22 | 2012 |
Population pharmacokinetics of vamorolone (VBP15) in healthy men and boys with Duchenne muscular dystrophy PD Mavroudis, J van den Anker, LS Conklin, JM Damsker, EP Hoffman, ... The Journal of Clinical Pharmacology 59 (7), 979-988, 2019 | 17 | 2019 |
Current approaches for predicting human PK for small molecule development candidates: Findings from the IQ human PK prediction working group survey C Petersson, X Zhou, J Berghausen, D Cebrian, M Davies, K DeMent, ... The AAPS journal 24 (5), 85, 2022 | 13 | 2022 |
A multiscale modeling approach to inflammation: A case study in human endotoxemia JD Scheff, PD Mavroudis, PT Foteinou, G An, SE Calvano, J Doyle, ... Journal of computational physics 244, 279-289, 2013 | 13 | 2013 |
Mathematical modeling of mammalian circadian clocks affecting drug and disease responses PD Mavroudis, WJ Jusko Journal of pharmacokinetics and pharmacodynamics 48 (3), 375-386, 2021 | 9 | 2021 |
On the unphysical hypotheses in pharmacokinetics and oral drug absorption: Time to utilize instantaneous rate coefficients instead of rate constants PD Mavroudis, K Kosmidis, P Macheras European Journal of Pharmaceutical Sciences 130, 137-146, 2019 | 7 | 2019 |
The impact of stochasticity and its control on a model of the inflammatory response PD Mavroudis, JD Scheff, JC Doyle, Y Vodovotz, IP Androulakis Computation 7 (1), 3, 2018 | 6 | 2018 |
Pathway-level analysis of genome-wide circadian dynamics in diverse tissues in rat and mouse A Acevedo, PD Mavroudis, D DuBois, RR Almon, WJ Jusko, ... Journal of pharmacokinetics and pharmacodynamics 48, 361-374, 2021 | 3 | 2021 |
ATLAS mPBPK: a MATLAb‐based tool for modeling and Simulation of minimal Physiologically Based PharmacoKinetic models PD Mavroudis, VS Ayyar, WJ Jusko CPT: pharmacometrics & systems pharmacology, 2019 | 3 | 2019 |