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Panteleimon D. Mavroudis
Panteleimon D. Mavroudis
Distinguished Scientist - US Head of Quantitative Pharmacology Research, Sanofi
Verified email at sanofi.com - Homepage
Title
Cited by
Cited by
Year
Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug
LS Conklin, JM Damsker, EP Hoffman, WJ Jusko, PD Mavroudis, ...
Pharmacological Research 136, 140-150, 2018
932018
Entrainment of peripheral clock genes by cortisol
PD Mavroudis, JD Scheff, SE Calvano, SF Lowry, IP Androulakis
Physiological genomics 44 (11), 607-621, 2012
802012
Systems biology of circadian-immune interactions
PD Mavroudis, JD Scheff, SE Calvano, IP Androulakis
Journal of innate immunity 5 (2), 153-162, 2013
642013
Modeling autonomic regulation of cardiac function and heart rate variability in human endotoxemia
JD Scheff, PD Mavroudis, SE Calvano, SF Lowry, IP Androulakis
Physiological genomics 43 (16), 951-964, 2011
612011
Circadian characteristics of permissive and suppressive effects of cortisol and their role in homeostasis and the acute inflammatory response
PD Mavroudis, SA Corbett, SE Calvano, IP Androulakis
Mathematical biosciences 260, 54-64, 2015
452015
Mathematical modeling of light-mediated HPA axis activity and downstream implications on the entrainment of peripheral clock genes
PD Mavroudis, SA Corbett, SE Calvano, IP Androulakis
Physiological genomics 46 (20), 766-778, 2014
452014
Daily variation of gene expression in diverse rat tissues
PD Mavroudis, DC DuBois, RR Almon, WJ Jusko
PloS one 13 (5), e0197258, 2018
382018
Machine learning guided early drug discovery of small molecules
N Pillai, A Dasgupta, S Sudsakorn, J Fretland, PD Mavroudis
Drug Discovery Today 27 (8), 2209-2215, 2022
282022
Development and validation of a physiology-based model for the prediction of pharmacokinetics/toxicokinetics in rabbits
PD Mavroudis, HE Hermes, D Teutonico, TG Preuss, S Schneckener
PloS one 13 (3), e0194294, 2018
242018
Translational applications of evaluating physiologic variability in human endotoxemia
JD Scheff, PD Mavroudis, SE Calvano, IP Androulakis
Journal of clinical monitoring and computing 27, 405-415, 2013
232013
Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat
PD Mavroudis, DC DuBois, RR Almon, WJ Jusko
PLoS One 13 (6), e0197534, 2018
222018
Modeling physiologic variability in human endotoxemia
JD Scheff, PD Mavroudis, PT Foteinou, SE Calvano, I Androulakis
Critical Reviews™ in Biomedical Engineering 40 (4), 2012
222012
Population pharmacokinetics of vamorolone (VBP15) in healthy men and boys with Duchenne muscular dystrophy
PD Mavroudis, J van den Anker, LS Conklin, JM Damsker, EP Hoffman, ...
The Journal of Clinical Pharmacology 59 (7), 979-988, 2019
172019
Current approaches for predicting human PK for small molecule development candidates: Findings from the IQ human PK prediction working group survey
C Petersson, X Zhou, J Berghausen, D Cebrian, M Davies, K DeMent, ...
The AAPS journal 24 (5), 85, 2022
132022
A multiscale modeling approach to inflammation: A case study in human endotoxemia
JD Scheff, PD Mavroudis, PT Foteinou, G An, SE Calvano, J Doyle, ...
Journal of computational physics 244, 279-289, 2013
132013
Mathematical modeling of mammalian circadian clocks affecting drug and disease responses
PD Mavroudis, WJ Jusko
Journal of pharmacokinetics and pharmacodynamics 48 (3), 375-386, 2021
92021
On the unphysical hypotheses in pharmacokinetics and oral drug absorption: Time to utilize instantaneous rate coefficients instead of rate constants
PD Mavroudis, K Kosmidis, P Macheras
European Journal of Pharmaceutical Sciences 130, 137-146, 2019
72019
The impact of stochasticity and its control on a model of the inflammatory response
PD Mavroudis, JD Scheff, JC Doyle, Y Vodovotz, IP Androulakis
Computation 7 (1), 3, 2018
62018
Pathway-level analysis of genome-wide circadian dynamics in diverse tissues in rat and mouse
A Acevedo, PD Mavroudis, D DuBois, RR Almon, WJ Jusko, ...
Journal of pharmacokinetics and pharmacodynamics 48, 361-374, 2021
32021
ATLAS mPBPK: a MATLAb‐based tool for modeling and Simulation of minimal Physiologically Based PharmacoKinetic models
PD Mavroudis, VS Ayyar, WJ Jusko
CPT: pharmacometrics & systems pharmacology, 2019
32019
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