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Justin Di Trani
Justin Di Trani
Assistant Professor of Biochemistry, University of Alberta
Verified email at ualberta.ca
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Year
Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response
D Sharon, S Cathelin, S Mirali, JM Di Trani, DJ Yanofsky, KA Keon, ...
Science translational medicine 11 (516), eaax2863, 2019
1512019
Shake-it-off: a simple ultrasonic cryo-EM specimen-preparation device
JL Rubinstein, H Guo, ZA Ripstein, A Haydaroglu, A Au, CM Yip, ...
Acta Crystallographica Section D: Structural Biology 75 (12), 1063-1070, 2019
682019
Rapid measurement of inhibitor binding kinetics by isothermal titration calorimetry
JM Di Trani, S De Cesco, R O¢Leary, J Plescia, CJ do Nascimento, ...
Nature Communications 9 (1), 893, 2018
592018
Cryo-EM structure and kinetics reveal electron transfer by 2D diffusion of cytochrome c in the yeast III-IV respiratory supercomplex
A Moe, J Di Trani, JL Rubinstein, P Brzezinski
Proceedings of the National Academy of Sciences 118 (11), e2021157118, 2021
502021
Efficient and rapid mechanochemical assembly of platinum (II) squares for guanine quadruplex targeting
A Garci, KJ Castor, J Fakhoury, JL Do, J Di Trani, P Chidchob, RS Stein, ...
Journal of the American Chemical Society 139 (46), 16913-16922, 2017
492017
Measuring rapid time-scale reaction kinetics using isothermal titration calorimetry
JM Di Trani, N Moitessier, AK Mittermaier
Analytical chemistry 89 (13), 7022-7030, 2017
402017
Structure of mycobacterial CIII2CIV2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203)
DJ Yanofsky, JM Di Trani, S Krol, R Abdelaziz, SA Bueler, P Imming, ...
Elife 10, e71959, 2021
262021
Exploring the role of post‐translational modifications in regulating á‐synuclein interactions by studying the effects of phosphorylation on nanobody binding
F El Turk, E De Genst, T Guilliams, B Fauvet, M Hejjaoui, J Di Trani, ...
Protein Science 27 (7), 1262-1274, 2018
262018
Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III
JM Di Trani, Z Liu, L Whitesell, P Brzezinski, LE Cowen, JL Rubinstein
Structure 30 (1), 129-138. e4, 2021
212021
Complete kinetic characterization of enzyme inhibition in a single isothermal titration calorimetric experiment
JM Di Trani, N Moitessier, AK Mittermaier
Analytical chemistry 90 (14), 8430-8435, 2018
202018
Integrated synthetic, biophysical, and computational investigations of covalent inhibitors of prolyl oligopeptidase and fibroblast activation protein á
J Plescia, S De Cesco, MB Patrascu, J Kurian, J Di Trani, C Dufresne, ...
Journal of Medicinal Chemistry 62 (17), 7874-7884, 2019
142019
Inhibition and activation of kinases by reaction products: a reporter-free assay
Y Wang, J Guan, JM Di Trani, K Auclair, AK Mittermaier
Analytical Chemistry 91 (18), 11803-11811, 2019
122019
Conformational plasticity surrounding the active site of NADH oxidase from Thermus thermophilus
T Miletti, J Di Trani, LC Jr. Levros, A Mittermaier
Protein Science 24 (7), 1114-1128, 2015
72015
Structural basis of mammalian complex IV inhibition by steroids
JM Di Trani, A Moe, D Riepl, P Saura, VRI Kaila, P Brzezinski, ...
Proceedings of the National Academy of Sciences 119 (30), e2205228119, 2022
62022
Flexible client-dependent cages in the assembly landscape of the periplasmic protease-chaperone DegP
RW Harkness, ZA Ripstein, JM Di Trani, LE Kay
Journal of the American Chemical Society 145 (24), 13015-13026, 2023
42023
Structure of the bc1cbb3 respiratory supercomplex from Pseudomonas aeruginosa
JM Di Trani, AA Gheorghita, M Turner, P Brzezinski, P Ädelroth, S Vahidi, ...
Proceedings of the National Academy of Sciences 120 (40), e2307093120, 2023
22023
Measuring enzyme kinetics using isothermal titration calorimetry
JM Di Trani
McGill University (Canada), 2019
22019
Imidazopyridine Amides: Synthesis, Mycobacterium smegmatis CIII2CIV2 Supercomplex Binding, and In Vitro Antimycobacterial Activity
R Abdelaziz, JM Di Trani, H Sahile, L Mann, A Richter, Z Liu, SA Bueler, ...
ACS omega 8 (21), 19081-19098, 2023
12023
High resolution cryo-EM of V-ATPase in native synaptic vesicles
CE Coupland, R Karimi, SA Bueler, Y Liang, GM Courbon, JM Di Trani, ...
bioRxiv, 2024.04. 01.587493, 2024
2024
Suggested searches
JN Druckman, S Kang, J Chu, MN Stagnaro, JG Voelkel, JS Mernyk, ...
Perspective, 2023
2023
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