PACT, a protein activator of the interferon‐induced protein kinase, PKR RC Patel, GC Sen The EMBO journal, 1998 | 581 | 1998 |
PACT, a stress-modulated cellular activator of interferon-induced double-stranded RNA-activated protein kinase, PKR CV Patel, I Handy, T Goldsmith, RC Patel Journal of Biological Chemistry 275 (48), 37993-37998, 2000 | 282 | 2000 |
The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo. RC Patel, P Stanton, NM McMillan, BR Williams, GC Sen Proceedings of the National Academy of Sciences 92 (18), 8283-8287, 1995 | 201 | 1995 |
Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase. RC Patel, GC Sen Journal of Biological Chemistry 267 (11), 7671-7676, 1992 | 167 | 1992 |
DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR RC Patel, DJ Vestal, Z Xu, S Bandyopadhyay, W Guo, SM Erme, ... Journal of Biological Chemistry 274 (29), 20432-20437, 1999 | 154 | 1999 |
TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress A Daher, G Laraki, M Singh, CE Melendez-Pena, S Bannwarth, ... Molecular and cellular biology, 2009 | 146 | 2009 |
Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties RC Patel, P Stanton, GC Sen Journal of Biological Chemistry 271 (41), 25657-25663, 1996 | 111 | 1996 |
The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR) X Huang, B Hutchins, RC Patel Biochemical Journal 366 (1), 175-186, 2002 | 95 | 2002 |
Activation of Interferon-inducible 2′− 5′ Oligoadenylate Synthetase by Adenoviral VAI RNA (∗) SY Desai, RC Patel, GC Sen, P Malhotra, GD Ghadge, B Thimmapaya Journal of Biological Chemistry 270 (7), 3454-3461, 1995 | 84 | 1995 |
Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast RC Patel, GC Sen Molecular and cellular biology 18 (12), 7009-7019, 1998 | 83 | 1998 |
AP-1 mediated transcriptional repression of matrix metalloproteinase-9 by recruitment of histone deacetylase 1 in response to interferon β ML Mittelstadt, RC Patel Public Library of Science 7 (8), e42152, 2012 | 82 | 2012 |
Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation M Singh, D Castillo, CV Patel, RC Patel Biochemistry 50 (21), 4550-4560, 2011 | 79 | 2011 |
The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity V Gupta, X Huang, RC Patel Virology 315 (2), 283-291, 2003 | 77 | 2003 |
Role of the amino-terminal residues of the interferon-induced protein kinase in its activation by double-stranded RNA and heparin RC Patel, P Stanton, GC Sen Journal of Biological Chemistry 269 (28), 18593-18598, 1994 | 75 | 1994 |
The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication G Clerzius, E Shaw, A Daher, S Burugu, JF Gélinas, T Ear, L Sinck, ... Retrovirology 10, 1-15, 2013 | 65 | 2013 |
Regulation of vascular smooth muscle proliferation by heparin: inhibition of cyclin-dependent kinase 2 activity by p27kip1 S Fasciano, RC Patel, I Handy, CV Patel Journal of Biological Chemistry 280 (16), 15682-15689, 2005 | 59 | 2005 |
Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis M Singh, V Fowlkes, I Handy, CV Patel, RC Patel Journal of molecular biology 385 (2), 457-468, 2009 | 58 | 2009 |
Altered activation of protein kinase PKR and enhanced apoptosis in dystonia cells carrying a mutation in PKR activator protein PACT LS Vaughn, DC Bragg, N Sharma, S Camargos, F Cardoso, RC Patel Journal of Biological Chemistry 290 (37), 22543-22557, 2015 | 57 | 2015 |
Increased interaction between PACT molecules in response to stress signals is required for PKR activation M Singh, RC Patel Journal of cellular biochemistry 113 (8), 2754-2764, 2012 | 57 | 2012 |
Homeobox gene HOXA9 inhibits nuclear factor-kappa B dependent activation of endothelium CM Trivedi, RC Patel, CV Patel Atherosclerosis 195 (2), e50-e60, 2007 | 49 | 2007 |