Troy E Sandberg
Troy E Sandberg
Principal Scientist, Capsida Biotherapeutics
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Human protein arginine methyltransferase 7 (PRMT7) is a type III enzyme forming ω-NG-monomethylated arginine residues
CI Zurita-Lopez, T Sandberg, R Kelly, SG Clarke
Journal of Biological Chemistry 287 (11), 7859-7870, 2012
The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology
TE Sandberg, MJ Salazar, LL Weng, BO Palsson, AM Feist
Metabolic engineering 56, 1-16, 2019
Use of adaptive laboratory evolution to discover key mutations enabling rapid growth of Escherichia coli K-12 MG1655 on glucose minimal medium
RA LaCroix, TE Sandberg, EJ O'Brien, J Utrilla, A Ebrahim, GI Guzman, ...
Applied and environmental microbiology 81 (1), 17-30, 2015
Evolution of Escherichia coli to 42 °C and Subsequent Genetic Engineering Reveals Adaptive Mechanisms and Novel Mutations
TE Sandberg, M Pedersen, RA LaCroix, A Ebrahim, M Bonde, ...
Molecular biology and evolution 31 (10), 2647-2662, 2014
Laboratory evolution to alternating substrate environments yields distinct phenotypic and genetic adaptive strategies
TE Sandberg, CJ Lloyd, BO Palsson, AM Feist
Applied and environmental microbiology 83 (13), e00410-17, 2017
Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism
D McCloskey, S Xu, TE Sandberg, E Brunk, Y Hefner, R Szubin, AM Feist, ...
Nature communications 9 (1), 1-15, 2018
Evolution of E. coli on [U-13C]Glucose Reveals a Negligible Isotopic Influence on Metabolism and Physiology
TE Sandberg, CP Long, JE Gonzalez, AM Feist, MR Antoniewicz, ...
PLoS One 11 (3), e0151130, 2016
Cellular responses to reactive oxygen species are predicted from molecular mechanisms
L Yang, N Mih, A Anand, JH Park, J Tan, JT Yurkovich, JM Monk, CJ Lloyd, ...
Proceedings of the National Academy of Sciences 116 (28), 14368-14373, 2019
Enzyme promiscuity shapes adaptation to novel growth substrates
GI Guzmán, TE Sandberg, RA LaCroix, Á Nyerges, H Papp, M de Raad, ...
Molecular systems biology 15 (4), e8462, 2019
Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism
C Cheng, EJ O’brien, D McCloskey, J Utrilla, C Olson, RA LaCroix, ...
PLoS computational biology 15 (6), e1007066, 2019
Adaptive laboratory evolution resolves energy depletion to maintain high aromatic metabolite phenotypes in Escherichia coli strains lacking the phosphotransferase system
D McCloskey, S Xu, TE Sandberg, E Brunk, Y Hefner, R Szubin, AM Feist, ...
Metabolic engineering 48, 233-242, 2018
Adaptation to the coupling of glycolysis to toxic methylglyoxal production in tpiA deletion strains of Escherichia coli requires synchronized and counterintuitive genetic changes
D McCloskey, S Xu, TE Sandberg, E Brunk, Y Hefner, R Szubin, AM Feist, ...
Metabolic engineering 48, 82-93, 2018
OxyR is a convergent target for mutations acquired during adaptation to oxidative stress-prone metabolic states
A Anand, K Chen, E Catoiu, AV Sastry, CA Olson, TE Sandberg, Y Seif, ...
Molecular biology and evolution 37 (3), 660-667, 2020
Growth Adaptation of gnd and sdhCB Escherichia coli Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome
D McCloskey, S Xu, TE Sandberg, E Brunk, Y Hefner, R Szubin, AM Feist, ...
Frontiers in microbiology 9, 1793, 2018
Multiple optimal phenotypes overcome redox and glycolytic intermediate metabolite imbalances in Escherichia coli pgi knockout evolutions
D McCloskey, S Xu, TE Sandberg, E Brunk, Y Hefner, R Szubin, AM Feist, ...
Applied and environmental microbiology, 342709, 2018
The genetic basis for adaptation of model-designed syntrophic co-cultures
CJ Lloyd, ZA King, TE Sandberg, Y Hefner, CA Olson, PV Phaneuf, ...
PLoS computational biology 15 (3), e1006213, 2019
Fast metabolic response to drug intervention through analysis on a miniaturized, highly integrated molecular imaging system
J Wang, K Hwang, D Braas, A Dooraghi, D Nathanson, DO Campbell, ...
Journal of nuclear medicine 54 (10), 1820-1824, 2013
Pseudogene repair driven by selection pressure applied in experimental evolution
A Anand, CA Olson, L Yang, AV Sastry, E Catoiu, KS Choudhary, ...
Nature microbiology 4 (3), 386-389, 2019
Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity
PV Phaneuf, JT Yurkovich, D Heckmann, M Wu, TE Sandberg, ZA King, ...
BMC genomics 21 (1), 1-16, 2020
Bacterial fitness landscapes stratify based on proteome allocation associated with discrete aero-types
K Chen, A Anand, C Olson, TE Sandberg, Y Gao, N Mih, BO Palsson
PLoS computational biology 17 (1), e1008596, 2021
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