| Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems N Nasongkla, E Bey, J Ren, H Ai, C Khemtong, JS Guthi, SF Chin, ... Nano letters 6 (11), 2427-2430, 2006 | 1503 | 2006 |
| Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases J Morales, L Li, FJ Fattah, Y Dong, EA Bey, M Patel, J Gao, DA Boothman Critical Reviews™ in Eukaryotic Gene Expression 24 (1), 2014 | 648 | 2014 |
| An NQO1-and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by â-lapachone EA Bey, MS Bentle, KE Reinicke, Y Dong, CR Yang, L Girard, JD Minna, ... Proceedings of the National Academy of Sciences 104 (28), 11832-11837, 2007 | 390 | 2007 |
| Superparamagnetic iron oxide nanoparticles: amplifying ROS stress to improve anticancer drug efficacy G Huang, H Chen, Y Dong, X Luo, H Yu, Z Moore, EA Bey, DA Boothman, ... Theranostics 3 (2), 116, 2013 | 327 | 2013 |
| Protein kinase Cä is required for p47phox phosphorylation and translocation in activated human monocytes EA Bey, B Xu, A Bhattacharjee, CM Oldfield, X Zhao, Q Li, ... The Journal of Immunology 173 (9), 5730-5738, 2004 | 208 | 2004 |
| â-Lapachone-containing PEG–PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells E Blanco, EA Bey, Y Dong, BD Weinberg, DM Sutton, DA Boothman, ... Journal of controlled release 122 (3), 365-374, 2007 | 207 | 2007 |
| Efficacy of beta-lapachone in pancreatic cancer treatment: exploiting the novel, therapeutic target NQO1 M Ough, A Lewis, EA Bey, J Gao, JM Ritchie, W Bornmann, DA Boothman, ... Cancer biology & therapy 4 (1), 102-109, 2005 | 201 | 2005 |
| Dual phosphoinositide 3-kinase/mammalian target of rapamycin blockade is an effective radiosensitizing strategy for the treatment of non–small cell lung cancer harboring K-RAS … G Konstantinidou, EA Bey, A Rabellino, K Schuster, MS Maira, AF Gazdar, ... Cancer research 69 (19), 7644-7652, 2009 | 171 | 2009 |
| â-Lapachone micellar nanotherapeutics for non–small cell lung cancer therapy E Blanco, EA Bey, C Khemtong, SG Yang, J Setti-Guthi, H Chen, ... Cancer research 70 (10), 3896-3904, 2010 | 170 | 2010 |
| An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis X Huang, Y Dong, EA Bey, JA Kilgore, JS Bair, LS Li, M Patel, ... Cancer research 72 (12), 3038-3047, 2012 | 155 | 2012 |
| Calcium-dependent modulation of poly (ADP-ribose) polymerase-1 alters cellular metabolism and DNA repair MS Bentle, KE Reinicke, EA Bey, DR Spitz, DA Boothman Journal of Biological Chemistry 281 (44), 33684-33696, 2006 | 154 | 2006 |
| Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of â-lapachone for pancreatic cancer therapy LS Li, EA Bey, Y Dong, J Meng, B Patra, J Yan, XJ Xie, RA Brekken, ... Clinical Cancer Research 17 (2), 275-285, 2011 | 121 | 2011 |
| Cytosolic phospholipase A2 (cPLA2) regulation of human monocyte NADPH oxidase activity: cPLA2 affects translocation but not phosphorylation of p67 phox and p47 phox X Zhao, EA Bey, FB Wientjes, MK Cathcart Journal of Biological Chemistry 277 (28), 25385-25392, 2002 | 118 | 2002 |
| Development of â-lapachone prodrugs for therapy against human cancer cells with elevated NAD (P) H: quinone oxidoreductase 1 levels KE Reinicke, EA Bey, MS Bentle, JJ Pink, ST Ingalls, CL Hoppel, ... Clinical Cancer Research 11 (8), 3055-3064, 2005 | 117 | 2005 |
| In vivo off-resonance saturation magnetic resonance imaging of ávâ3-targeted superparamagnetic nanoparticles C Khemtong, CW Kessinger, J Ren, EA Bey, SG Yang, JS Guthi, ... Cancer research 69 (4), 1651-1658, 2009 | 115 | 2009 |
| Leveraging an NQO1 bioactivatable drug for tumor-selective use of poly (ADP-ribose) polymerase inhibitors X Huang, EA Motea, ZR Moore, J Yao, Y Dong, G Chakrabarti, JA Kilgore, ... Cancer cell 30 (6), 940-952, 2016 | 113 | 2016 |
| Catalase abrogates â-lapachone–induced PARP1 hyperactivation–directed programmed necrosis in NQO1-positive breast cancers EA Bey, KE Reinicke, MC Srougi, M Varnes, VE Anderson, JJ Pink, LS Li, ... Molecular cancer therapeutics 12 (10), 2110-2120, 2013 | 105 | 2013 |
| Prostate cancer radiosensitization through poly (ADP-Ribose) polymerase-1 hyperactivation Y Dong, EA Bey, LS Li, W Kabbani, J Yan, XJ Xie, JT Hsieh, J Gao, ... Cancer research 70 (20), 8088-8096, 2010 | 99 | 2010 |
| Intratumoral delivery of â-lapachone via polymer implants for prostate cancer therapy Y Dong, SF Chin, E Blanco, EA Bey, W Kabbani, XJ Xie, WG Bornmann, ... Clinical Cancer Research 15 (1), 131-139, 2009 | 91 | 2009 |
| New tricks for old drugs: the anticarcinogenic potential of DNA repair inhibitors MS Bentle, EA Bey, Y Dong, KE Reinicke, DA Boothman Journal of molecular histology 37, 203-218, 2006 | 84 | 2006 |
