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Christophe Laroche
Christophe Laroche
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Year
Lewis acid activation of chiral 2-trifluoromethyl-1, 3-oxazolidines. Application to the stereoselective synthesis of trifluoromethylated amines, α-and β-amino acids
N Lebouvier, C Laroche, F Huguenot, T Brigaud
Tetrahedron letters 43 (15), 2827-2830, 2002
922002
Coupling Reactions of Bromoalkynes with Imidazoles Mediated by Copper Salts: Synthesis of Novel N-Alkynylimidazoles
C Laroche, J Li, MW Freyer, SM Kerwin
The Journal of Organic Chemistry 73 (16), 6462-6465, 2008
842008
Spirocyclopropyl pyrrolidines as a new series of α-L-fucosidase inhibitors
C Laroche, JB Behr, J Szymoniak, P Bertus, C Schütz, P Vogel, ...
Bioorganic & medicinal chemistry 14 (12), 4047-4054, 2006
752006
Titanium-mediated synthesis of bicyclic cyclopropylamines from unsaturated nitriles
C Laroche, P Bertus, J Szymoniak
Tetrahedron letters 44 (12), 2485-2487, 2003
492003
Studies on the titanium-catalyzed cyclopropanation of nitriles
C Laroche, D Harakat, P Bertus, J Szymoniak
Organic & Biomolecular Chemistry 3 (19), 3482-3487, 2005
402005
Efficient, Regioselective Access to Bicyclic Imidazo[1,2-x]- Heterocycles via Gold- and Base-Promoted Cyclization of 1-Alkynylimidazoles
C Laroche, SM Kerwin
The Journal of Organic Chemistry 74 (23), 9229-9232, 2009
352009
Synthesis and biological evaluation of p38α kinase-targeting dialkynylimidazoles
J Li, TS Kaoud, C Laroche, KN Dalby, SM Kerwin
Bioorganic & medicinal chemistry letters 19 (22), 6293-6297, 2009
262009
Lithiation and functionalization of 1-alkynylimidazoles at the 2-position
C Laroche, SM Kerwin
Tetrahedron Letters 50 (37), 5194-5197, 2009
262009
Cytotoxic 1, 2-dialkynylimidazole-based aza-enediynes: Aza-Bergman rearrangement rates do not predict cytotoxicity
C Laroche, J Li, SM Kerwin
Journal of medicinal chemistry 54 (14), 5059-5069, 2011
242011
Pentadienyl transfer reagents based on zirconium: preparation and reactions with carbonyl compounds
P Bertus, L Drouin, C Laroche, J Szymoniak
Tetrahedron 60 (6), 1375-1383, 2004
192004
Cyclization kinetics and biological evaluation of an anticancer 1, 2-dialkynylimidazole
C Laroche, J Li, C Gonzales, WM David, SM Kerwin
Organic & biomolecular chemistry 8 (7), 1535-1539, 2010
162010
Exploring the synthetic utility of 1-alkynylimidazoles: Regiocontrolled cyclization to diverse imidazoazines and imidazoazoles
C Laroche, B Gilbreath, SM Kerwin
Tetrahedron 70 (30), 4534-4539, 2014
142014
Ti‐Mediated Synthesis of Aminocyclopropyl‐Substituted Carbohydrates
C Laroche, JB Behr, J Szymoniak, P Bertus, R Plantier‐Royon
European journal of organic chemistry 2005 (23), 5084-5088, 2005
142005
Titanium-mediated [4+ 1] assembly of 1, 3-dienes and nitriles: formation of 3-cyclopentenyl amines and cyclopentenones
C Laroche, P Bertus, J Szymoniak
Chemical communications, 3030-3032, 2005
122005
Asymmetric titanium-catalyzed cyclopropanation of nitriles with Grignard reagents
J Caillé, P Setzer, F Boeda, MSM Pearson-Long, P Bertus
SynOpen 2 (01), 0041-0049, 2018
112018
Aminopyridine derivatives for removal of hydrogen sulfide from a gas mixture
CR Laroche, G Padilla
US Patent 9,421,492, 2016
112016
Zirconium-mediated conversion of homoallylic ethers into cyclopropane derivatives
V Gandon, C Laroche, J Szymoniak
Tetrahedron letters 44 (26), 4827-4829, 2003
112003
Copper-catalyzed synthesis of fused imidazopyrazine N-oxide skeletons
V Taşdemir, B Kuzu, M Tan, H Genç, N Menges
Synlett 30 (03), 307-310, 2019
92019
Zinc-mediated double addition on functionalized nitriles
J Caillé, M Pantin, F Boeda, MSM Pearson-Long, P Bertus
Synthesis 51 (06), 1329-1341, 2019
82019
Aqueous alkanolamine composition and process for the removal of acid gases from gaseous mixtures
CR Laroche, G Padilla, TD Halnon
US Patent 9,468,882, 2016
82016
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