Lewis acid activation of chiral 2-trifluoromethyl-1, 3-oxazolidines. Application to the stereoselective synthesis of trifluoromethylated amines, α-and β-amino acids N Lebouvier, C Laroche, F Huguenot, T Brigaud Tetrahedron letters 43 (15), 2827-2830, 2002 | 92 | 2002 |
Coupling Reactions of Bromoalkynes with Imidazoles Mediated by Copper Salts: Synthesis of Novel N-Alkynylimidazoles C Laroche, J Li, MW Freyer, SM Kerwin The Journal of Organic Chemistry 73 (16), 6462-6465, 2008 | 84 | 2008 |
Spirocyclopropyl pyrrolidines as a new series of α-L-fucosidase inhibitors C Laroche, JB Behr, J Szymoniak, P Bertus, C Schütz, P Vogel, ... Bioorganic & medicinal chemistry 14 (12), 4047-4054, 2006 | 75 | 2006 |
Titanium-mediated synthesis of bicyclic cyclopropylamines from unsaturated nitriles C Laroche, P Bertus, J Szymoniak Tetrahedron letters 44 (12), 2485-2487, 2003 | 49 | 2003 |
Studies on the titanium-catalyzed cyclopropanation of nitriles C Laroche, D Harakat, P Bertus, J Szymoniak Organic & Biomolecular Chemistry 3 (19), 3482-3487, 2005 | 40 | 2005 |
Efficient, Regioselective Access to Bicyclic Imidazo[1,2-x]- Heterocycles via Gold- and Base-Promoted Cyclization of 1-Alkynylimidazoles C Laroche, SM Kerwin The Journal of Organic Chemistry 74 (23), 9229-9232, 2009 | 35 | 2009 |
Synthesis and biological evaluation of p38α kinase-targeting dialkynylimidazoles J Li, TS Kaoud, C Laroche, KN Dalby, SM Kerwin Bioorganic & medicinal chemistry letters 19 (22), 6293-6297, 2009 | 26 | 2009 |
Lithiation and functionalization of 1-alkynylimidazoles at the 2-position C Laroche, SM Kerwin Tetrahedron Letters 50 (37), 5194-5197, 2009 | 26 | 2009 |
Cytotoxic 1, 2-dialkynylimidazole-based aza-enediynes: Aza-Bergman rearrangement rates do not predict cytotoxicity C Laroche, J Li, SM Kerwin Journal of medicinal chemistry 54 (14), 5059-5069, 2011 | 24 | 2011 |
Pentadienyl transfer reagents based on zirconium: preparation and reactions with carbonyl compounds P Bertus, L Drouin, C Laroche, J Szymoniak Tetrahedron 60 (6), 1375-1383, 2004 | 19 | 2004 |
Cyclization kinetics and biological evaluation of an anticancer 1, 2-dialkynylimidazole C Laroche, J Li, C Gonzales, WM David, SM Kerwin Organic & biomolecular chemistry 8 (7), 1535-1539, 2010 | 16 | 2010 |
Exploring the synthetic utility of 1-alkynylimidazoles: Regiocontrolled cyclization to diverse imidazoazines and imidazoazoles C Laroche, B Gilbreath, SM Kerwin Tetrahedron 70 (30), 4534-4539, 2014 | 14 | 2014 |
Ti‐Mediated Synthesis of Aminocyclopropyl‐Substituted Carbohydrates C Laroche, JB Behr, J Szymoniak, P Bertus, R Plantier‐Royon European journal of organic chemistry 2005 (23), 5084-5088, 2005 | 14 | 2005 |
Titanium-mediated [4+ 1] assembly of 1, 3-dienes and nitriles: formation of 3-cyclopentenyl amines and cyclopentenones C Laroche, P Bertus, J Szymoniak Chemical communications, 3030-3032, 2005 | 12 | 2005 |
Asymmetric titanium-catalyzed cyclopropanation of nitriles with Grignard reagents J Caillé, P Setzer, F Boeda, MSM Pearson-Long, P Bertus SynOpen 2 (01), 0041-0049, 2018 | 11 | 2018 |
Aminopyridine derivatives for removal of hydrogen sulfide from a gas mixture CR Laroche, G Padilla US Patent 9,421,492, 2016 | 11 | 2016 |
Zirconium-mediated conversion of homoallylic ethers into cyclopropane derivatives V Gandon, C Laroche, J Szymoniak Tetrahedron letters 44 (26), 4827-4829, 2003 | 11 | 2003 |
Copper-catalyzed synthesis of fused imidazopyrazine N-oxide skeletons V Taşdemir, B Kuzu, M Tan, H Genç, N Menges Synlett 30 (03), 307-310, 2019 | 9 | 2019 |
Zinc-mediated double addition on functionalized nitriles J Caillé, M Pantin, F Boeda, MSM Pearson-Long, P Bertus Synthesis 51 (06), 1329-1341, 2019 | 8 | 2019 |
Aqueous alkanolamine composition and process for the removal of acid gases from gaseous mixtures CR Laroche, G Padilla, TD Halnon US Patent 9,468,882, 2016 | 8 | 2016 |