A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling J Qian, S Olbrecht, B Boeckx, H Vos, D Laoui, E Etlioglu, E Wauters, ... Cell research 30 (9), 745-762, 2020 | 445 | 2020 |
A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer A Bassez, H Vos, L Van Dyck, G Floris, I Arijs, C Desmedt, B Boeckx, ... Nature medicine 27 (5), 820-832, 2021 | 387 | 2021 |
HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development CE de Bock, S Demeyer, S Degryse, D Verbeke, B Sweron, O Gielen, ... Cancer discovery 8 (5), 616-631, 2018 | 101 | 2018 |
Cooperative enhancer activation by TLX1 and STAT5 drives development of NUP214-ABL1/TLX1-positive T cell acute lymphoblastic leukemia MV Bempt, S Demeyer, M Broux, J De Bie, S Bornschein, N Mentens, ... Cancer cell 34 (2), 271-285. e7, 2018 | 51 | 2018 |
Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia M Broux, C Prieto, S Demeyer, M Vanden Bempt, L Alberti-Servera, ... Blood, The Journal of the American Society of Hematology 134 (16), 1323-1336, 2019 | 40 | 2019 |
Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL S Degryse, S Bornschein, CE de Bock, E Leroy, M Vanden Bempt, ... Blood, The Journal of the American Society of Hematology 131 (4), 421-425, 2018 | 35 | 2018 |
Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC-and TPM3-ALK fusions is characterized by copy number gain of the rearranged … JA van der Krogt, MV Bempt, JF Ferreiro, N Mentens, K Jacobs, U Pluys, ... Haematologica 102 (9), 1605, 2017 | 35 | 2017 |
Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified K Debackere, L Marcelis, S Demeyer, M Vanden Bempt, N Mentens, ... Nature communications 12 (1), 3705, 2021 | 21 | 2021 |
Generation of the Fip1l1–Pdgfra fusion gene using CRISPR/Cas genome editing M Vanden Bempt, S Demeyer, N Mentens, E Geerdens, CE De Bock, ... Leukemia 30 (9), 1913-1916, 2016 | 15 | 2016 |
Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma M Vanden Bempt, K Debackere, S Demeyer, Q Van Thillo, N Meeuws, ... Blood, The Journal of the American Society of Hematology 140 (23), 2463-2476, 2022 | 13 | 2022 |
EML1–ABL1 Is Activated by Coiled-Coil-Mediated Oligomerization and Induces T-Cell Acute Lymphoblastic Leukemia or Myeloproliferative Disease in a Mouse Bone Marrow Transplant Model MV Bempt, N Mentens, P Vandenberghe, J Cools, K De Keersmaecker Hemasphere 2 (2), e32, 2018 | 3 | 2018 |
Dual targeting of EZH2 and Histone Deacetylases in hematological malignancies promotes transcriptional and metabolic deregulation leading to ferroptosis A Veloso, T Slegers, J Schoenaker, S Demeyer, S Van den Bergh, ... bioRxiv, 2024.03. 03.583195, 2024 | | 2024 |
3001–ABERRANT MYCN OVEREXPRESSION DRIVES ONCOGENIC HIJACKING OF EZH2 AS A TRANSCRIPTIONAL ACTIVATOR IN PERIPHERAL T CELL LYMPHOMA. MV Bempt, K Debackere, A Veloso, S Demeyer, T Slegers, Q Van Thillo, ... Experimental Hematology 124, S51, 2023 | | 2023 |
P1297: ABERRANT MYCN EXPRESSION DRIVES ONCOGENIC HIJACKING OF EZH2 AS A TRANSCRIPTIONAL ACTIVATOR IN PERIPHERAL T CELL LYMPHOMA MV Bempt, K Debackere, S Demeyer, Q Van Thillo, N Meeuws, J Cools, ... HemaSphere 6, 1182-1183, 2022 | | 2022 |
THE NUP214-ABL1 FUSION COOPERATES WITH TLX1 IN THE DEVELOPMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA MV Bempt, CE de Bock, S Demeyer, R Vandepoel, N Mentens, ... Haematologica 101, 27-27, 2016 | | 2016 |
Use of CRISPR/Cas genome editing in Ba/F3 cells to generate the Fip1l1-Pdgfra and Nup214-Abl1 fusion genes MV Bempt, CE de Bock, N Mentens, O Gielen, E Geerdens, S Demeyer, ... Blood 124 (21), 3575, 2014 | | 2014 |
FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T cell lymphoma, not otherwise specified K Debackere, L Marcelis, S e Demeyer, MV Bempt, N Mentens, O Gielen, ... | | |