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Karan M Shah
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Effects of cobalt and chromium ions at clinically equivalent concentrations after metal-on-metal hip replacement on human osteoblasts and osteoclasts: implications for skeletal …
RE Andrews, KM Shah, JM Wilkinson, A Gartland
Bone 49 (4), 717-723, 2011
1372011
Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis
J Steinberg, GRS Ritchie, TI Roumeliotis, RL Jayasuriya, MJ Clark, ...
Scientific reports 7 (1), 1-11, 2017
1072017
Strategies for articular cartilage repair and regeneration
Y Liu, KM Shah, J Luo
Frontiers in Bioengineering and Biotechnology 9, 770655, 2021
732021
A molecular quantitative trait locus map for osteoarthritis
J Steinberg, L Southam, TI Roumeliotis, MJ Clark, RL Jayasuriya, D Swift, ...
Nature Communications 12 (1), 1309, 2021
592021
PGE2 activates EP4 in subchondral bone osteoclasts to regulate osteoarthritis
W Jiang, Y Jin, S Zhang, Y Ding, K Huo, J Yang, L Zhao, B Nian, ...
Bone research 10 (1), 27, 2022
572022
Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5
K Hatzikotoulas, A Roposch, KM Shah, MJ Clark, S Bratherton, V Limbani, ...
Communications biology 1 (1), 56, 2018
532018
Osteocyte isolation and culture methods
KM Shah, MM Stern, AR Stern, JL Pathak, N Bravenboer, AD Bakker
BoneKEy reports 5, 2016
492016
Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis
J Steinberg, L Southam, A Fontalis, MJ Clark, RL Jayasuriya, D Swift, ...
Annals of the Rheumatic Diseases 80 (8), 1070-1074, 2021
312021
Cobalt and chromium exposure affects osteoblast function and impairs the mineralization of prosthesis surfaces in vitro
KM Shah, JM Wilkinson, A Gartland
Journal of Orthopaedic Research® 33 (11), 1663-1670, 2015
312015
Understanding the tissue effects of tribo‐corrosion: Uptake, distribution, and speciation of cobalt and chromium in human bone cells
JMW Karan M Shah, Paul D Quinn, Alison Gartland
Journal of Orthopaedic Research 33 (1), 114-121, 2015
272015
Effects of chronic cobalt and chromium exposure after metal‐on‐metal hip resurfacing: an epigenome‐wide association pilot study
J Steinberg, KM Shah, A Gartland, E Zeggini, JM Wilkinson
Journal of Orthopaedic Research 35 (10), 2323-2328, 2017
242017
A novel prostaglandin E receptor 4 (EP4) small molecule antagonist induces articular cartilage regeneration
Y Jin, Q Liu, P Chen, S Zhao, W Jiang, F Wang, P Li, Y Zhang, W Lu, ...
Cell Discovery 8 (1), 24, 2022
212022
The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties
L Tattersall, KM Shah, DL Lath, A Singh, JM Down, E De Marchi, ...
Journal of Bone Oncology 31, 100398, 2021
182021
Osteocyte physiology and response to fluid shear stress are impaired following exposure to cobalt and chromium: Implications for bone health following joint replacement
KM Shah, P Orton, N Mani, JM Wilkinson, A Gartland
Journal of Orthopaedic Research 35 (8), 1716-1723, 2017
162017
The 2018 Otto Aufranc Award: How does genome-wide variation affect osteolysis risk after THA?
SJ MacInnes, K Hatzikotoulas, AM Fenstad, K Shah, L Southam, ...
Clinical Orthopaedics and Related Research® 477 (2), 297-309, 2019
142019
JZL184, a monoacylglycerol lipase inhibitor, induces bone loss in a multiple myeloma model of immunocompetent mice
S Marino, G Carrasco, B Li, KM Shah, DL Lath, A Sophocleous, ...
Calcified Tissue International 107, 72-85, 2020
122020
Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis. Sci Rep. 2017; 7: 8935
J Steinberg, GRS Ritchie, TI Roumeliotis, RL Jayasuriya, MJ Clark, ...
Ann Rheum Dis: first published as 10, 0
9
Decoding the genomic basis of osteoarthritis
J Steinberg, L Southam, NC Butterfield, TI Roumeliotis, A Fontalis, ...
BioRxiv, 835850, 2019
72019
The strategy and clinical relevance of in vitro models of MAP resistance in osteosarcoma: a systematic review
VL Tippett, L Tattersall, NB Ab Latif, KM Shah, MA Lawson, A Gartland
Oncogene 42 (4), 259-277, 2023
52023
Distinct concentration-dependent molecular pathways regulate bone cell responses to cobalt and chromium exposure from joint replacement prostheses
KM Shah, MJ Dunning, A Gartland, JM Wilkinson
International Journal of Molecular Sciences 22 (10), 5225, 2021
42021
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Articles 1–20