Παρακολούθηση
Steven Warner
Steven Warner
Tolero Pharmaceuticals
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα toleropharma.com
Τίτλος
Παρατίθεται από
Παρατίθεται από
Έτος
An epithelial–mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor …
LA Byers, L Diao, J Wang, P Saintigny, L Girard, M Peyton, L Shen, Y Fan, ...
Clinical cancer research 19 (1), 279-290, 2013
10032013
Targeting Axl and Mer kinases in cancer
A Verma, SL Warner, H Vankayalapati, DJ Bearss, S Sharma
Molecular cancer therapeutics 10 (10), 1763-1773, 2011
2622011
Targeting Aurora-2 kinase in cancer
SL Warner, DJ Bearss, H Han, DD Von Hoff
Molecular cancer therapeutics 2 (6), 589-595, 2003
2332003
High-Throughput Virtual Screening Identifies Novel N′-(1-Phenylethylidene)-benzohydrazides as Potent, Specific, and Reversible LSD1 Inhibitors
V Sorna, ER Theisen, B Stephens, SL Warner, DJ Bearss, ...
Journal of medicinal chemistry 56 (23), 9496-9508, 2013
2032013
S110, a 5-Aza-2′-Deoxycytidine–Containing Dinucleotide, Is an Effective DNA Methylation Inhibitor In vivo and Can Reduce Tumor Growth
JC Chuang, SL Warner, D Vollmer, H Vankayalapati, S Redkar, ...
Molecular cancer therapeutics 9 (5), 1443-1450, 2010
1762010
Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells
SL Warner, BJ Stephens, S Nwokenkwo, G Hostetter, A Sugeng, ...
Clinical Cancer Research 15 (21), 6519-6528, 2009
1612009
Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia
IK Park, B Mundy-Bosse, SP Whitman, X Zhang, SL Warner, DJ Bearss, ...
Leukemia 29 (12), 2382-2389, 2015
1582015
A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas
JM Foulks, KJ Carpenter, B Luo, Y Xu, A Senina, R Nix, A Chan, A Clifford, ...
Neoplasia 16 (5), 403-412, 2014
1122014
Design, synthesis, and biological evaluation of a series of novel AXL kinase inhibitors
A Mollard, SL Warner, LT Call, ML Wade, JJ Bearss, A Verma, S Sharma, ...
ACS medicinal chemistry letters 2 (12), 907-912, 2011
962011
Activators of PKM2 in cancer metabolism
SL Warner, KJ Carpenter, DJ Bearss
Future medicinal chemistry 6 (10), 1167-1178, 2014
932014
AXL inhibition suppresses the DNA damage response and sensitizes cells to PARP inhibition in multiple cancers
K Balaji, S Vijayaraghavan, L Diao, P Tong, Y Fan, JPW Carey, TN Bui, ...
Molecular Cancer Research 15 (1), 45-58, 2017
862017
TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase
X Wang, H Saso, T Iwamoto, W Xia, Y Gong, L Pusztai, WA Woodward, ...
Cancer research 73 (21), 6516-6525, 2013
862013
Identification of a lead small-molecule inhibitor of the Aurora kinases using a structure-assisted, fragment-based approach
SL Warner, S Bashyam, H Vankayalapati, DJ Bearss, H Han, DD Von Hoff, ...
Molecular cancer therapeutics 5 (7), 1764-1773, 2006
862006
Combined venetoclax and alvocidib in acute myeloid leukemia
J Bogenberger, C Whatcott, N Hansen, D Delman, CX Shi, W Kim, ...
Oncotarget 8 (63), 107206, 2017
762017
Targeted Axl inhibition primes chronic lymphocytic leukemia B cells to apoptosis and shows synergistic/additive effects in combination with BTK inhibitors
S Sinha, J Boysen, M Nelson, C Secreto, SL Warner, DJ Bearss, ...
Clinical Cancer Research 21 (9), 2115-2126, 2015
732015
Substituted tricyclic compounds as protein kinase inhibitors
LH Hurley, D Mahadevan, DJ Bearss, H Vankayalapati, S Bashyam, ...
US Patent 7,326,712, 2008
71*2008
Comparing Aurora A and Aurora B as molecular targets for growth inhibition of pancreatic cancer cells
SL Warner, RM Munoz, P Stafford, E Koller, LH Hurley, DD Von Hoff, ...
Molecular cancer therapeutics 5 (10), 2450-2458, 2006
672006
Protein Kinase Inhibitors
LH Hurley, D Mahadevan, H Han, DJ Bearss, H Vankayalapati, ...
US Patent App. 11/735,344, 2009
612009
Tubulin-associated drug targets: Aurora kinases, Polo-like kinases, and others
SL Warner, PJ Gray, DD Von Hoff
Seminars in oncology 33 (4), 436-448, 2006
562006
Substituted N-phenylpyrimidin-2-amine analogs as inhibitors of the Axl kinase
DJ Bearss, H Vankayalapati, A Mollard, SL Warner, S Sharma
US Patent 8,901,120, 2014
492014
Δεν είναι δυνατή η εκτέλεση της ενέργειας από το σύστημα αυτή τη στιγμή. Προσπαθήστε ξανά αργότερα.
Άρθρα 1–20