DCyFIR: a high-throughput CRISPR platform for multiplexed G protein-coupled receptor profiling and ligand discovery NJ Kapolka, GJ Taghon, JB Rowe, WM Morgan, JF Enten, NA Lambert, ... Proceedings of the National Academy of Sciences 117 (23), 13117-13126, 2020 | 54 | 2020 |
Predictable cholesterol binding sites in GPCRs lack consensus motifs GJ Taghon, JB Rowe, NJ Kapolka, DG Isom Structure 29 (5), 499-506. e3, 2021 | 46 | 2021 |
The evolution and mechanism of GPCR proton sensing JB Rowe, NJ Kapolka, GJ Taghon, WM Morgan, DG Isom Journal of Biological Chemistry 296, 2021 | 43 | 2021 |
Proton-gated coincidence detection is a common feature of GPCR signaling N Kapolka, J Rowe, G Taghon, W Morgan, C O'Shea, D Isom Proceedings of the National Academy of Sciences 118, 2021 | 17 | 2021 |
Submicron aggregation of chemically denatured monoclonal antibody JB Rowe, RP Flynn, HR Wooten, HA Noufer, RA Cancel, J Zhang, ... Molecular Pharmaceutics 15 (10), 4710-4721, 2018 | 16 | 2018 |
CRISPR-addressable yeast strains with applications in human G protein–coupled receptor profiling and synthetic biology JB Rowe, GJ Taghon, NJ Kapolka, WM Morgan, DG Isom Journal of Biological Chemistry 295 (24), 8262-8271, 2020 | 12 | 2020 |
Metastability gap in the phase diagram of monoclonal IgG antibody JB Rowe, RA Cancel, TD Evangelous, RP Flynn, S Pechenov, ... Biophysical Journal 113 (8), 1750-1756, 2017 | 11 | 2017 |
Location-biased activation of the proton-sensor GPR65 is uncoupled from receptor trafficking LM Morales Rodríguez, SE Crilly, JB Rowe, DG Isom, MA Puthenveedu Proceedings of the National Academy of Sciences 120 (39), e2302823120, 2023 | 3* | 2023 |
Designer Autocrine Signaling Networks for Discovering GPCR-modulating Nanobodies J Rowe, K Lee, S Taylor, D Isom Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
Quantifying Acid Adaptivity of Normal and Cancer Cells Using a Next Generation Genetically Encoded pH Biosensor D Isom, S Taylor, K Lee, J Rowe Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
Methods for Identifying Modulators of G Protein-Coupled Receptors D Isom, W Morgan, N Kapolka, G Taghon, J Rowe US Patent App. 17/785,524, 2023 | | 2023 |
A Study on the Thermodynamics of Phase Transitions in Monoclonal Antibody Solutions JB Rowe University of North Carolina Wilmington, 2017 | | 2017 |
Scalable Platforms and Technologies for Discovering GPCR Mechanisms and Pharmacological Modulators JB Rowe University of Miami, 0 | | |