| All ras proteins are polyisoprenylated but only some are palmitoylated JF Hancock, AI Magee, JE Childs, CJ Marshall Cell 57 (7), 1167-1177, 1989 | 2301 | 1989 |
| A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane JF Hancock, H Paterson, CJ Marshall Cell 63 (1), 133-139, 1990 | 1416 | 1990 |
| Activation of Raf as a result of recruitment to the plasma membrane SM Hancock JF, Stokoe D, Macdonald SG, Cadwallader K Science 264, 1463-1467, 1994 | 1241 | 1994 |
| Ras proteins: different signals from different locations JF Hancock Nature reviews Molecular cell biology 4 (5), 373-385, 2003 | 1105 | 2003 |
| Lipid rafts: contentious only from simplistic standpoints JF Hancock Nature Reviews Molecular Cell Biology 7 (6), 456-462, 2006 | 990 | 2006 |
| Direct visualization of Ras proteins in spatially distinct cell surface microdomains IA Prior, C Muncke, RG Parton, JF Hancock Journal of Cell Biology 160 (2), 165-170, 2003 | 894 | 2003 |
| PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function MM Hill, M Bastiani, R Luetterforst, M Kirkham, A Kirkham, SJ Nixon, ... Cell 132 (1), 113-124, 2008 | 799 | 2008 |
| Signalling ballet in space and time BN Kholodenko, JF Hancock, W Kolch Nature reviews Molecular cell biology 11 (6), 414-426, 2010 | 712 | 2010 |
| A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins JF Hancock, K Cadwaller, H Paterson, CJ Marshall The EMBO Journal 10 (13), 4033-4039, 1991 | 669 | 1991 |
| GTP-dependent segregation of H-ras from lipid rafts is required for biological activity IA Prior, A Harding, J Yan, J Sluimer, RG Parton, JF Hancock Nature cell biology 3 (4), 368-375, 2001 | 661 | 2001 |
| Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase J Yan, S Roy, A Apolloni, A Lane, JF Hancock Journal of Biological Chemistry 273 (37), 24052-24056, 1998 | 630 | 1998 |
| Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains S Roy, R Luetterforst, A Harding, A Apolloni, M Etheridge, E Stang, ... Nature cell biology 1 (2), 98-105, 1999 | 602 | 1999 |
| Post‐translational processing of p21ras is two‐step and involves carboxyl‐methylation and carboxy‐terminal proteolysis. L Gutierrez, AI Magee, CJ Marshall, JF Hancock The EMBO journal 8 (4), 1093-1098, 1989 | 586 | 1989 |
| H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway A Apolloni, IA Prior, M Lindsay, RG Parton, JF Hancock Molecular and Cellular Biology 20 (7), 2475-2487, 2000 | 570 | 2000 |
| H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton SJ Plowman, C Muncke, RG Parton, JF Hancock Proceedings of the National Academy of Sciences 102 (43), 15500-15505, 2005 | 531 | 2005 |
| Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles M Kirkham, A Fujita, R Chadda, SJ Nixon, TV Kurzchalia, DK Sharma, ... The Journal of cell biology 168 (3), 465-476, 2005 | 525 | 2005 |
| The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product C Calés, JF Hancock, CJ Marshall, A Hall Nature 332 (6164), 548-551, 1988 | 471 | 1988 |
| Plasma membrane nanoswitches generate high-fidelity Ras signal transduction T Tian, A Harding, K Inder, S Plowman, RG Parton, JF Hancock Nature cell biology 9 (8), 905-914, 2007 | 440 | 2007 |
| Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K‐ras (B). JF Hancock, K Cadwallader, CJ Marshall The EMBO journal 10 (3), 641-646, 1991 | 402 | 1991 |
| Lipid rafts and membrane traffic MF Hanzal-Bayer, JF Hancock FEBS letters 581 (11), 2098-2104, 2007 | 389 | 2007 |
