p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1á (HIF-1á) and enhance the transcriptional activity of HIF-1 DE Richard, E Berra, E Gothié, D Roux, J Pouysségur Journal of Biological Chemistry 274 (46), 32631-32637, 1999 | 1052 | 1999 |
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1á in vascular smooth muscle cells DE Richard, E Berra, J Pouysségur Journal of Biological Chemistry 275 (35), 26765-26771, 2000 | 872 | 2000 |
Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators MAC Déry, MD Michaud, DE Richard The international journal of biochemistry & cell biology 37 (3), 535-540, 2005 | 760 | 2005 |
Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1á CC Blouin, EL Pagé, GM Soucy, DE Richard Blood 103 (3), 1124-1130, 2004 | 549 | 2004 |
Induction of hypoxia-inducible factor-1á by transcriptional and translational mechanisms EL Pagé, GA Robitaille, J Pouysségur, DE Richard Journal of Biological Chemistry 277 (50), 48403-48409, 2002 | 514 | 2002 |
Transforming growth factor â1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression S McMahon, M Charbonneau, S Grandmont, DE Richard, CM Dubois Journal of Biological Chemistry 281 (34), 24171-24181, 2006 | 379 | 2006 |
Transforming growth factor â1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression S McMahon, M Charbonneau, S Grandmont, DE Richard, CM Dubois Journal of Biological Chemistry 281 (34), 24171-24181, 2006 | 379 | 2006 |
Angiogenesis: how a tumor adapts to hypoxia DE Richard, E Berra, J Pouysségur Biochemical and biophysical research communications 266 (3), 718-722, 1999 | 302 | 1999 |
Signaling angiogenesis via p42/p44 MAP kinase and hypoxia E Berra, J Milanini, DE Richard, M Le Gall, F Viñals, E Gothié, D Roux, ... Biochemical pharmacology 60 (8), 1171-1178, 2000 | 280 | 2000 |
Hypoxia‐inducible factor‐1á (HIF‐1á) escapes O2‐driven proteasomal degradation irrespective of its subcellular localization: nucleus or cytoplasm E Berra, D Roux, DE Richard, J Pouysségur EMBO reports, 2001 | 239 | 2001 |
Hypoxia-inducible factor-1á stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion EL Pagé, DA Chan, AJ Giaccia, M Levine, DE Richard Molecular biology of the cell 19 (1), 86-94, 2008 | 214 | 2008 |
Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: impact on the bioactivation of proproteins S McMahon, F Grondin, PP McDonald, DE Richard, CM Dubois Journal of Biological Chemistry 280 (8), 6561-6569, 2005 | 211 | 2005 |
HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1á degradation E Berra, DE Richard, E Gothié, J Pouysségur FEBS letters 491 (1-2), 85-90, 2001 | 194 | 2001 |
Inflammatory cytokines and reactive oxygen species as mediators of chronic kidney disease-related vascular calcification M Agharazii, R St-Louis, A Gautier-Bastien, RV Ung, S Mokas, R Larivière, ... American journal of hypertension 28 (6), 746-755, 2015 | 187 | 2015 |
Hypoxia-inducible factor-1 activation in nonhypoxic conditions: the essential role of mitochondrial-derived reactive oxygen species DA Patten, VN Lafleur, GA Robitaille, DA Chan, AJ Giaccia, DE Richard Molecular biology of the cell 21 (18), 3247-3257, 2010 | 184 | 2010 |
Signaling angiogenesis via p42/p44 MAP kinase cascade G Pages, J Milanini, DE Richard, E Berra, E Gothie, F Vinals, ... Annals of the New York Academy of Sciences 902 (1), 187-200, 2000 | 167 | 2000 |
Identification of alternative spliced variants of human hypoxia-inducible factor-1á E Gothié, DE Richard, E Berra, G Pages, J Pouysségur Journal of Biological Chemistry 275 (10), 6922-6927, 2000 | 156 | 2000 |
Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1á and is not induced by hypoxia or HIF R Bilton, N Mazure, E Trottier, M Hattab, MA Déry, DE Richard, ... Journal of Biological Chemistry 280 (35), 31132-31140, 2005 | 138 | 2005 |
Hypoxia-inducible factor-1 plays a role in phosphate-induced vascular smooth muscle cell calcification S Mokas, R Larivière, L Lamalice, S Gobeil, DN Cornfield, M Agharazii, ... Kidney international 90 (3), 598-609, 2016 | 134 | 2016 |
Angiogenesis and G-protein-coupled receptors: signals that bridge the gap DE Richard, V Vouret-Craviari, J Pouysségur Oncogene 20 (13), 1556-1562, 2001 | 131 | 2001 |