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Kejin Zhou
Kejin Zhou
Founder, Reinvigoron TheraTech Inc.
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Year
A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals
Y Wang, K Zhou, G Huang, C Hensley, X Huang, X Ma, T Zhao, BD Sumer, ...
Nature materials 13 (2), 204-212, 2014
7202014
Tunable, ultrasensitive pH‐responsive nanoparticles targeting specific endocytic organelles in living cells
K Zhou, Y Wang, X Huang, K Luby‐Phelps, BD Sumer, J Gao
Angewandte Chemie International Edition 50 (27), 6109-6114, 2011
5332011
Non‐viral CRISPR/Cas gene editing in vitro and in vivo enabled by synthetic nanoparticle co‐delivery of Cas9 mRNA and sgRNA
JB Miller, S Zhang, P Kos, H Xiong, K Zhou, SS Perelman, H Zhu, ...
Angewandte Chemie 129 (4), 1079-1083, 2017
5322017
Multicolored pH-tunable and activatable fluorescence nanoplatform responsive to physiologic pH stimuli
K Zhou, H Liu, S Zhang, X Huang, Y Wang, G Huang, BD Sumer, J Gao
Journal of the American Chemical Society 134 (18), 7803-7811, 2012
3392012
The polyploid state plays a tumor-suppressive role in the liver
S Zhang, K Zhou, X Luo, L Li, HC Tu, A Sehgal, LH Nguyen, Y Zhang, ...
Developmental cell 44 (4), 447-459. e5, 2018
1752018
Dendrimer‐based lipid nanoparticles deliver therapeutic FAH mRNA to normalize liver function and extend survival in a mouse model of hepatorenal tyrosinemia type I
Q Cheng, T Wei, Y Jia, L Farbiak, K Zhou, S Zhang, Y Wei, H Zhu, ...
Advanced materials 30 (52), 1805308, 2018
1642018
Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model
K Zhou, LH Nguyen, JB Miller, Y Yan, P Kos, H Xiong, L Li, J Hao, ...
Proceedings of the National Academy of Sciences 113 (3), 520-525, 2016
1482016
The coil-to-globule-to-coil transition of linear polymer chains in dilute aqueous solutions: effect of intrachain hydrogen bonding
K Zhou, Y Lu, J Li, L Shen, G Zhang, Z Xie, C Wu
Macromolecules 41 (22), 8927-8931, 2008
1142008
Knockdown of anillin actin binding protein blocks cytokinesis in hepatocytes and reduces liver tumor development in mice without affecting regeneration
S Zhang, LH Nguyen, K Zhou, HC Tu, A Sehgal, I Nassour, L Li, P Gopal, ...
Gastroenterology 154 (5), 1421-1434, 2018
1082018
Origin of hysteresis observed in association and dissociation of polymer chains in water
Y Lu, K Zhou, Y Ding, G Zhang, C Wu
Physical Chemistry Chemical Physics 12 (13), 3188-3194, 2010
1012010
Rapid synthesis of a lipocationic polyester library via ring-opening polymerization of functional valerolactones for efficacious siRNA delivery
J Hao, P Kos, K Zhou, JB Miller, L Xue, Y Yan, H Xiong, S Elkassih, ...
Journal of the American Chemical Society 137 (29), 9206-9209, 2015
962015
Tumor-activated water-soluble photosensitizers for near-infrared photodynamic cancer therapy
H Xiong, K Zhou, Y Yan, JB Miller, DJ Siegwart
ACS applied materials & interfaces 10 (19), 16335-16343, 2018
932018
Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti–PD-L1 to eliminate melanoma in mice
Y Wang, L Su, MD Morin, BT Jones, Y Mifune, H Shi, K Wang, X Zhan, ...
Proceedings of the National Academy of Sciences 115 (37), E8698-E8706, 2018
922018
Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells
Y Yan, L Liu, H Xiong, JB Miller, K Zhou, P Kos, KE Huffman, S Elkassih, ...
Proceedings of the National Academy of Sciences 113 (39), E5702-E5710, 2016
782016
Re-examination of Dynamics of Polyeletrolytes in Salt-Free Dilute Solutions by Designing and Using a Novel Neutral− Charged− Neutral Reversible Polymer
K Zhou, J Li, Y Lu, G Zhang, Z Xie, C Wu
Macromolecules 42 (18), 7146-7154, 2009
762009
Aerosol delivery of stabilized polyester-siRNA nanoparticles to silence gene expression in orthotopic lung tumors
Y Yan, K Zhou, H Xiong, JB Miller, EA Motea, DA Boothman, L Liu, ...
Biomaterials 118, 84-93, 2017
672017
High‐contrast fluorescence detection of metastatic breast cancer including bone and liver micrometastases via size‐controlled pH‐Activatable water‐soluble probes
H Xiong, H Zuo, Y Yan, G Occhialini, K Zhou, Y Wan, DJ Siegwart
Advanced Materials 29 (29), 1700131, 2017
662017
Precise let-7 expression levels balance organ regeneration against tumor suppression
L Wu, LH Nguyen, K Zhou, TY de Soysa, L Li, JB Miller, J Tian, J Locker, ...
Elife 4, e09431, 2015
642015
Activatable water-soluble probes enhance tumor imaging by responding to dysregulated pH and exhibiting high tumor-to-liver fluorescence emission contrast
H Xiong, P Kos, Y Yan, K Zhou, JB Miller, S Elkassih, DJ Siegwart
Bioconjugate chemistry 27 (7), 1737-1744, 2016
602016
Chaotropic‐anion‐induced supramolecular self‐assembly of ionic polymeric micelles
Y Li, Y Wang, G Huang, X Ma, K Zhou, J Gao
Angewandte Chemie 126 (31), 8212-8216, 2014
502014
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