Human iPSC-derived natural killer cells engineered with chimeric antigen receptors enhance anti-tumor activity Y Li, DL Hermanson, BS Moriarity, DS Kaufman Cell stem cell 23 (2), 181-192. e5, 2018 | 778 | 2018 |
PVT1 dependence in cancer with MYC copy-number increase YY Tseng, BS Moriarity, W Gong, R Akiyama, A Tiwari, H Kawakami, ... Nature 512 (7512), 82-86, 2014 | 746 | 2014 |
Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells P Kebriaei, H Singh, MH Huls, MJ Figliola, R Bassett, S Olivares, B Jena, ... The Journal of clinical investigation 126 (9), 3363-3376, 2016 | 525 | 2016 |
EditR: a method to quantify base editing from Sanger sequencing MG Kluesner, DA Nedveck, WS Lahr, JR Garbe, JE Abrahante, ... The CRISPR journal 1 (3), 239-250, 2018 | 348 | 2018 |
Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling M Zuckermann, V Hovestadt, CB Knobbe-Thomsen, M Zapatka, ... Nature communications 6 (1), 7391, 2015 | 307 | 2015 |
The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14 JM Park, CH Jung, M Seo, NM Otto, D Grunwald, KH Kim, B Moriarity, ... Autophagy 12 (3), 547-564, 2016 | 295 | 2016 |
A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis BS Moriarity, GM Otto, EP Rahrmann, SK Rathe, NK Wolf, MT Weg, ... Nature genetics 47 (6), 615-624, 2015 | 256 | 2015 |
Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis EP Rahrmann, AL Watson, VW Keng, K Choi, BS Moriarity, DA Beckmann, ... Nature genetics 45 (7), 756-766, 2013 | 177 | 2013 |
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors BR Webber, C Lonetree, MG Kluesner, MJ Johnson, EJ Pomeroy, ... Nature communications 10 (1), 5222, 2019 | 163 | 2019 |
A genetically engineered primary human natural killer cell platform for cancer immunotherapy EJ Pomeroy, JT Hunzeker, MG Kluesner, WS Lahr, BA Smeester, ... Molecular Therapy 28 (1), 52-63, 2020 | 136 | 2020 |
Canonical Wnt/β-catenin signaling drives human Schwann cell transformation, progression, and tumor maintenance AL Watson, EP Rahrmann, BS Moriarity, K Choi, CB Conboy, AD Greeley, ... Cancer discovery 3 (6), 674-689, 2013 | 113 | 2013 |
Efficient targeted integration directed by short homology in zebrafish and mammalian cells WA Wierson, JM Welker, MP Almeida, CM Mann, DA Webster, ME Torrie, ... Elife 9, e53968, 2020 | 103 | 2020 |
Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression, and survival in osteosarcoma MC Scott, NA Temiz, AE Sarver, RS LaRue, SK Rathe, J Varshney, ... Cancer research 78 (2), 326-337, 2018 | 99 | 2018 |
A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma L Mirabello, R Koster, BS Moriarity, LG Spector, PS Meltzer, J Gary, ... Cancer discovery 5 (9), 920-931, 2015 | 94 | 2015 |
CRISPR/Cas9 library screening for drug target discovery M Kurata, K Yamamoto, BS Moriarity, M Kitagawa, DA Largaespada Journal of Human Genetics 63 (2), 179-186, 2018 | 87 | 2018 |
Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3 R Chaudhary, B Gryder, WS Woods, M Subramanian, MF Jones, XL Li, ... Elife 6, e23244, 2017 | 83 | 2017 |
Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments ED Tabdanov, NJ Rodríguez-Merced, AX Cartagena-Rivera, VV Puram, ... Nature communications 12 (1), 2815, 2021 | 82 | 2021 |
mTORC1 coordinates protein synthesis and immunoproteasome formation via PRAS40 to prevent accumulation of protein stress YS Yun, KH Kim, B Tschida, Z Sachs, KE Noble-Orcutt, BS Moriarity, T Ai, ... Molecular cell 61 (4), 625-639, 2016 | 77 | 2016 |
Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML M Kurata, SK Rathe, NJ Bailey, NK Aumann, JM Jones, GW Veldhuijzen, ... Scientific reports 6 (1), 36199, 2016 | 68 | 2016 |
Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR VW Keng, D Sia, AL Sarver, BR Tschida, D Fan, C Alsinet, M Solé, ... Hepatology 57 (1), 120-130, 2013 | 67 | 2013 |