Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection C Yao, HW Sun, NE Lacey, Y Ji, EA Moseman, HY Shih, EF Heuston, ... Nature immunology 20 (7), 890-901, 2019 | 439 | 2019 |
Immunosurveillance of the liver by intravascular effector CD8+ T cells LG Guidotti, D Inverso, L Sironi, P Di Lucia, J Fioravanti, L Ganzer, ... Cell 161 (3), 486-500, 2015 | 310 | 2015 |
Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity D Hermans, S Gautam, JC García-Cañaveras, D Gromer, S Mitra, ... Proceedings of the National Academy of Sciences 117 (11), 6047-6055, 2020 | 155 | 2020 |
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy TN Yamamoto, PH Lee, SK Vodnala, D Gurusamy, RJ Kishton, Z Yu, ... The Journal of clinical investigation 129 (4), 1551-1565, 2019 | 138 | 2019 |
The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity S Gautam, J Fioravanti, W Zhu, JB Le Gall, P Brohawn, NE Lacey, J Hu, ... Nature immunology 20 (3), 337-349, 2019 | 135 | 2019 |
Successful colon cancer eradication after chemoimmunotherapy is associated with profound phenotypic change of intratumoral myeloid cells J Medina-Echeverz, J Fioravanti, M Zabala, N Ardaiz, J Prieto, ... The Journal of Immunology 186 (2), 807-815, 2011 | 128 | 2011 |
Inflammatory monocytes hinder antiviral B cell responses S Sammicheli, M Kuka, P Di Lucia, NJ de Oya, M De Giovanni, ... Science Immunology 1 (4), eaah6789, 2016 | 100 | 2016 |
miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate Y Ji, J Fioravanti, W Zhu, H Wang, T Wu, J Hu, NE Lacey, S Gautam, ... Nature communications 10 (1), 2157, 2019 | 63 | 2019 |
Effector CD8+ T cell-derived interleukin-10 enhances acute liver immunopathology J Fioravanti, P Di Lucia, D Magini, F Moalli, C Boni, AP Benechet, ... Journal of hepatology 67 (3), 543-548, 2017 | 55 | 2017 |
Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin C Mansilla, P Berraondo, M Durantez, M Martínez, N Casares, ... International Journal of Cancer 131 (3), 641-651, 2012 | 54 | 2012 |
Anchoring interferon alpha to apolipoprotein A‐I reduces hematological toxicity while enhancing immunostimulatory properties J Fioravanti, I González, J Medina‐Echeverz, E Larrea, N Ardaiz, ... Hepatology 53 (6), 1864-1873, 2011 | 54 | 2011 |
Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein MC Ochoa, J Fioravanti, I Rodriguez, S Hervas-Stubbs, A Azpilikueta, ... Cancer research 73 (1), 139-149, 2013 | 53 | 2013 |
The fusion protein of IFN-α and apolipoprotein AI crosses the blood–brain barrier by a saturable transport mechanism J Fioravanti, J Medina-Echeverz, N Ardaiz, C Gomar, ZP Parra-Guillén, ... The Journal of Immunology 188 (8), 3988-3992, 2012 | 29 | 2012 |
A Semliki forest virus vector engineered to express IFNα induces efficient elimination of established tumors JI Quetglas, J Fioravanti, N Ardaiz, J Medina-Echeverz, I Baraibar, J Prieto, ... Gene therapy 19 (3), 271-278, 2012 | 29 | 2012 |
Scavenger receptor class B, type I: a promising immunotherapy target J Fioravanti, J Medina-Echeverz, P Berraondo Immunotherapy 3 (3), 395-406, 2011 | 24 | 2011 |
Liver-directed gene therapy of chronic hepadnavirus infection using interferon alpha tethered to apolipoprotein AI P Berraondo, M Di Scala, K Korolowicz, LM Thampi, I Otano, L Suarez, ... Journal of hepatology 63 (2), 329-336, 2015 | 23 | 2015 |
Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases J Medina-Echeverz, J Fioravanti, N Díaz-Valdés, K Frank, F Aranda, ... PLoS One 9 (5), e96799, 2014 | 18 | 2014 |
Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy MC Ochoa, J Fioravanti, EH Duitman, J Medina-Echeverz, A Palazon, ... PLoS One 7 (12), e52370, 2012 | 18 | 2012 |
Pathogen‐specific B‐cell receptors drive chronic lymphocytic leukemia by light‐chain‐dependent cross‐reaction with autoantigens N Jiménez de Oya, M De Giovanni, J Fioravanti, R Übelhart, P Di Lucia, ... EMBO molecular medicine 9 (11), 1482-1490, 2017 | 16 | 2017 |
Interferon alpha bioactivity critically depends on Scavenger receptor class B type I function M Vasquez, J Fioravanti, F Aranda, V Paredes, C Gomar, N Ardaiz, ... Oncoimmunology 5 (8), e1196309, 2016 | 13 | 2016 |