Mahmoud Alhosin
Mahmoud Alhosin
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The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression
M Achour, X Jacq, P Ronde, M Alhosin, C Charlot, T Chataigneau, ...
Oncogene 27 (15), 2187-2197, 2008
Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1
M Alhosin, A Abusnina, M Achour, T Sharif, C Muller, J Peluso, ...
Biochemical pharmacology 79 (9), 1251-1260, 2010
Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties
M Alhosin, T Sharif, M Mousli, N Etienne-Selloum, G Fuhrmann, ...
Journal of Experimental & Clinical Cancer Research 30, 1-10, 2011
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
M Alhosin, Z Omran, MA Zamzami, AL Al-Malki, H Choudhry, M Mousli, ...
Journal of Experimental & Clinical Cancer Research 35, 1-11, 2016
The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer
W Ashraf, A Ibrahim, M Alhosin, L Zaayter, K Ouararhni, C Papin, ...
Oncotarget 8 (31), 51946, 2017
Coordinated dialogue between UHRF1 and DNMT1 to ensure faithful inheritance of methylated DNA patterns
C Bronner, M Alhosin, A Hamiche, M Mousli
Genes 10 (1), 65, 2019
UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity
M Achour, G Fuhrmann, M Alhosin, P Rondé, T Chataigneau, M Mousli, ...
Biochemical and biophysical research communications 390 (3), 523-528, 2009
Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1
M Achour, M Mousli, M Alhosin, A Ibrahim, J Peluso, CD Muller, ...
Biochemical and biophysical research communications 430 (1), 208-212, 2013
Red wine polyphenols cause growth inhibition and apoptosis in acute lymphoblastic leukaemia cells by inducing a redox-sensitive up-regulation of p73 and down-regulation of UHRF1
T Sharif, C Auger, M Alhosin, C Ebel, M Achour, N Étienne-Selloum, ...
European journal of cancer 46 (5), 983-994, 2010
Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis
A Abusnina, M Alhosin, T Keravis, CD Muller, G Fuhrmann, C Bronner, ...
Cellular signalling 23 (1), 152-160, 2011
Limoniastrum guyonianum aqueous gall extract induces apoptosis in human cervical cancer cells involving p16INK4A re-expression related to UHRF1 and …
M Krifa, M Alhosin, CD Muller, JP Gies, L Chekir-Ghedira, K Ghedira, ...
Journal of Experimental & Clinical Cancer Research 32, 1-10, 2013
Aronia melanocarpa juice induces a redox-sensitive p73-related caspase 3-dependent apoptosis in human leukemia cells
T Sharif, M Alhosin, C Auger, C Minker, JH Kim, N Etienne-Selloum, ...
PloS one 7 (3), e32526, 2012
Probiotics (VSL# 3) prevent endothelial dysfunction in rats with portal hypertension: role of the angiotensin system
SK Rashid, NI Khodja, C Auger, M Alhosin, N Boehm, ...
PloS one 9 (5), e97458, 2014
Anti-neoplastic agent thymoquinone induces degradation of α and β tubulin proteins in human cancer cells without affecting their level in normal human fibroblasts
M Alhosin, A Ibrahim, A Boukhari, T Sharif, JP Gies, C Auger, ...
Investigational new drugs 30, 1813-1819, 2012
Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway
M Alhosin, AJ León-González, I Dandache, A Lelay, SK Rashid, C Kevers, ...
Scientific reports 5 (1), 8996, 2015
CD47 activation-induced UHRF1 over-expression is associated with silencing of tumor suppressor gene p16INK4A in glioblastoma cells
A Boukhari, M Alhosin, C Bronner, K Sagini, C Truchot, E Sick, ...
Anticancer research 35 (1), 149-157, 2015
Redox-sensitive induction of Src/PI3-kinase/Akt and MAPKs pathways activate eNOS in response to EPA: DHA 6: 1
F Zgheel, M Alhosin, S Rashid, M Burban, C Auger, VB Schini-Kerth
PloS one 9 (8), e105102, 2014
Redox-sensitive up-regulation of eNOS by purple grape juice in endothelial cells: role of PI3-kinase/Akt, p38 MAPK, JNK, FoxO1 and FoxO3a
M Alhosin, E Anselm, S Rashid, JH Kim, SV Frota Madeira, C Bronner, ...
PLoS One 8 (3), e57883, 2013
Thymoquinone-induced reactivation of tumor suppressor genes in cancer cells involves epigenetic mechanisms
SA Qadi, MA Hassan, RA Sheikh, OAS Baothman, MA Zamzami, ...
Epigenetics insights 12, 2516865719839011, 2019
Selective proapoptotic activity of polyphenols from red wine on teratocarcinoma cell, a model of cancer stem-like cell
T Sharif, C Auger, C Bronner, M Alhosin, T Klein, N Etienne-Selloum, ...
Investigational new drugs 29, 239-247, 2011
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