| Sildenafil (VIAGRATM), a potent and selective inhibitor of type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction NK Terrett, AS Bell, D Brown, P Ellis Bioorganic & medicinal chemistry letters 6 (15), 1819-1824, 1996 | 807 | 1996 |
| Pyrazolopyrimidinone antianginal agents AS Bell, D Brown, NK Terrett US Patent 5,250,534, 1993 | 205 | 1993 |
| Novel antifungal 2-aryl-1-(1H-1, 2, 4-triazol-1-yl) butan-2-ol derivatives with high activity against Aspergillus fumigatus RP Dickinson, AS Bell, CA Hitchcock, S Narayanaswami, SJ Ray, ... Bioorganic & Medicinal Chemistry Letters 6 (16), 2031-2036, 1996 | 120 | 1996 |
| Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus A Mousnier, AS Bell, DP Swieboda, J Morales-Sanfrutos, I Pérez-Dorado, ... Nature chemistry 10 (6), 599-606, 2018 | 104 | 2018 |
| PDE9 inhibitors for treating type 2 diabetes, metabolic syndrome, and cardiovascular disease A Bell, M DeNinno, M Palmer, M Visser US Patent App. 10/828,485, 2004 | 104 | 2004 |
| Selective Inhibitors of Protozoan Protein N-myristoyltransferases as Starting Points for Tropical Disease Medicinal Chemistry Programs AS Bell, JE Mills, GP Williams, JA Brannigan, AJ Wilkinson, T Parkinson, ... PLoS neglected tropical diseases 6 (4), e1625, 2012 | 97 | 2012 |
| Pyrazolopyrimidinone antianginal agents AS Bell, D Brown, NK Terrett US Patent 5,346,901, 1994 | 92 | 1994 |
| Intermediates useful in the synthesis of pyrazolopyrimidinone antianginal agents AS Bell, D Brown, NK Terrett US Patent 5,719,283, 1998 | 87 | 1998 |
| The accelerated development of an optimized synthesis of 1, 2, 4-oxadiazoles: application of microwave irradiation and statistical design of experiments MD Evans, J Ring, A Schoen, A Bell, P Edwards, D Berthelot, ... Tetrahedron letters 44 (52), 9337-9341, 2003 | 86 | 2003 |
| Pyrazolopyrimidinone antianginal agents AS Bell, NK Terrett US Patent 5,426,107, 1995 | 81 | 1995 |
| N-Myristoyltransferase as a potential drug target in malaria and leishmaniasis EW Tate, AS Bell, MD Rackham, MH Wright Parasitology 141 (1), 37-49, 2014 | 78 | 2014 |
| A synthesis of 2-and 4 (5)-(2-pyridinyl) imidazoles by palladium-catalysed cross-coupling reactions AS Bell, DA Roberts, KS Ruddock Tetrahedron letters 29 (39), 5013-5016, 1988 | 73 | 1988 |
| Structure-Based Design of Potent and Selective Leishmania N-Myristoyltransferase Inhibitors JA Hutton, V Goncalves, JA Brannigan, D Paape, MH Wright, TM Waugh, ... Journal of medicinal chemistry 57 (20), 8664-8670, 2014 | 71 | 2014 |
| 5-substituted pyrazolo [4, 3-D] pyrimidin-7-ones AS Bell, NK Terrett US Patent 6,235,742, 2001 | 71 | 2001 |
| 2 (1H)-Quinolinones with cardiac stimulant activity. 1. Synthesis and biological activities of (six-membered heteroaryl)-substituted derivatives CT Alabaster, AS Bell, SF Campbell, P Ellis, CG Henderson, DA Roberts, ... Journal of medicinal chemistry 31 (10), 2048-2056, 1988 | 64 | 1988 |
| 5, 7-diaminopyrazolo4, 3-d! pyrimidines useful in the treatment of hypertension AS Bell, DG Brown, DNA Fox, IR Marsh, AI Morrell, MJ Palmer, ... | 62 | 2004 |
| 2 (1H)-Quinolinones with cardiac stimulant activity. 2. Synthesis and biological activities of 6-(N-linked, five-membered heteroaryl) derivatives CT Alabaster, AS Bell, SF Campbell, P Ellis, CG Henderson, DS Morris, ... Journal of medicinal chemistry 32 (3), 575-583, 1989 | 58 | 1989 |
| The discovery of potent, selective, and orally bioavailable PDE9 inhibitors as potential hypoglycemic agents MP DeNinno, M Andrews, AS Bell, Y Chen, C Eller-Zarbo, N Eshelby, ... Bioorganic & medicinal chemistry letters 19 (9), 2537-2541, 2009 | 55 | 2009 |
| Pyrazolopyrimidinone antianginal agents AS Bell, NK Terrett US Patent 5,272,147, 1993 | 55 | 1993 |
| Design of second generation phosphodiesterase 5 inhibitors MJ Palmer, AS Bell, DNA Fox, DG Brown Current Topics in Medicinal Chemistry 7 (4), 405-419, 2007 | 52 | 2007 |
