| Potentiator ivacaftor abrogates pharmacological correction of ÄF508 CFTR in cystic fibrosis DM Cholon, NL Quinney, ML Fulcher, CR Esther Jr, J Das, NV Dokholyan, ... Science translational medicine 6 (246), 246ra96-246ra96, 2014 | 360 | 2014 |
| Subdiffusion and lateral diffusion coefficient of lipid atoms and molecules in phospholipid bilayers E Flenner, J Das, MC Rheinstädter, I Kosztin Physical Review E 79 (1), 011907, 2009 | 124 | 2009 |
| Pharmacological chaperones: design and development of new therapeutic strategies for the treatment of conformational diseases M Convertino, J Das, NV Dokholyan ACS chemical biology 11 (6), 1471-1489, 2016 | 98 | 2016 |
| Non-canonical base pairs and higher order structures in nucleic acids: crystal structure database analysis J Das, S Mukherjee, A Mitra, D Bhattacharyya Journal of Biomolecular Structure and Dynamics 24 (2), 149-161, 2006 | 88 | 2006 |
| Motional coherence in fluid phospholipid membranes MC Rheinstädter, J Das, EJ Flenner, B Brüning, T Seydel, I Kosztin Physical Review Letters 101 (24), 248106, 2008 | 62 | 2008 |
| Protein destabilization as a common factor in diverse inherited disorders RL Redler, J Das, JR Diaz, NV Dokholyan Journal of molecular evolution 82, 11-16, 2016 | 58 | 2016 |
| Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770 M Gentzsch, HY Ren, SA Houck, NL Quinney, DM Cholon, P Sopha, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (3 …, 2016 | 39 | 2016 |
| Anomalous diffusion of water molecules in hydrated lipid bilayers J Das, E Flenner, I Kosztin The Journal of Chemical Physics 139 (6), 2013 | 30 | 2013 |
| Anomalous diffusion of water molecules in hydrated lipid bilayers J Das, E Flenner, I Kosztin The Journal of Chemical Physics 139 (6), 2013 | 30 | 2013 |
| Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology AJ Green, MJ Mohlenkamp, J Das, M Chaudhari, L Truong, RL Tanguay, ... PLOS Computational Biology 17 (7), e1009135, 2021 | 28 | 2021 |
| A modified PATH algorithm rapidly generates transition states comparable to those found by other well established algorithms SN Chandrasekaran, J Das, NV Dokholyan, CW Carter Structural Dynamics 3 (1), 2016 | 26 | 2016 |
| ApoE4-specific misfolded intermediate identified by molecular dynamics simulations B Williams II, M Convertino, J Das, NV Dokholyan PLoS computational biology 11 (10), e1004359, 2015 | 25 | 2015 |
| Restructuring of hydrophobic surfaces created by surfactant adsorption to mica surfaces J Das, C Eun, S Perkin, ML Berkowitz Langmuir 27 (19), 11737-11741, 2011 | 25 | 2011 |
| Transmembrane helical interactions in the CFTR channel pore J Das, AA Aleksandrov, L Cui, L He, JR Riordan, NV Dokholyan PLoS computational biology 13 (6), e1005594, 2017 | 12 | 2017 |
| Thermodynamic impacts of combinatorial mutagenesis on protein conformational stability: precise, high-throughput measurement by Thermofluor V Weinreb, G Weinreb, SN Chandrasekaran, J Das, NV Dokholyan, ... BioRxiv, 591495, 2019 | 3 | 2019 |
| Potentiator ivacaftor abrogates pharmacological correction of ÄF508 CFTR in cystic fibrosis. Sci Transl Med. 2014; 6: 246ra96 DM Cholon, NL Quinney, ML Fulcher, CR Esther, J Das, NV Dokholyan | 3 | |
| Molecular Mechanisms of the R61T Mutation in Apolipoprotein E4: A Dynamic Rescue B Williams, M Convertino, J Das, NV Dokholyan Biophysical journal 113 (10), 2192-2198, 2017 | 2 | 2017 |
| Microcalorimetry reveals multi-state thermal denaturation of G. stearothermophilus tryptophanyl-tRNA synthetase SN Chandrasekaran, J Das, NV Dokholyan, CW Carter Structural Dynamics 10 (4), 2023 | 1 | 2023 |
| Leveraging high-throughput screening data and conditional generative adversarial networks to advance predictive toxicology AJ Green, MJ Mohlenkamp, J Das, M Chaudhari, L Truong, RL Tanguay, ... bioRxiv, 2020.10. 02.322917, 2020 | 1 | 2020 |
| Knowledge-Based Models: RNA R Méndez, A Krokhotin, M Convertino, J Das, A Tandon, NV Dokholyan Coarse-Grained Modeling of Biomolecules, 221-270, 2017 | 1 | 2017 |
Nikolay DokholyanG. Thomas Passananti ProfessorVerified email at psu.edu
