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| Preliminary biochemical characterization of two angiotensin II receptor subtypes S Whitebread, M Mele, B Kamber, M de Gasparo Biochemical and biophysical research communications 163 (1), 284-291, 1989 | 987 | 1989 |
| Large-scale prediction and testing of drug activity on side-effect targets E Lounkine, MJ Keiser, S Whitebread, D Mikhailov, J Hamon, JL Jenkins, ... Nature 486 (7403), 361-367, 2012 | 927 | 2012 |
| Reducing safety-related drug attrition: the use of in vitro pharmacological profiling J Bowes, AJ Brown, J Hamon, W Jarolimek, A Sridhar, G Waldron, ... Nature reviews Drug discovery 11 (12), 909-922, 2012 | 747 | 2012 |
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| Three new epoxy-spirolactone derivatives: characterization in vivo and in vitro. M De Gasparo, U Joss, HP Ramjoue, SE Whitebread, H Haenni, ... Journal of Pharmacology and Experimental Therapeutics 240 (2), 650-656, 1987 | 422 | 1987 |
| Analysis of pharmacology data and the prediction of adverse drug reactions and off‐target effects from chemical structure A Bender, J Scheiber, M Glick, JW Davies, K Azzaoui, J Hamon, L Urban, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 861-873, 2007 | 391 | 2007 |
| Pharmacological profile of valsartan: a potent, orally active, nonpeptide antagonist of the angiotensin II AT1‐receptor subtype L Criscione, M de Gasparo, P Bühlmayer, S Whitebread, HR Ramjoué, ... British journal of pharmacology 110 (2), 761-771, 1993 | 318 | 1993 |
| Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor. L Criscione, P Rigollier, C Batzl-Hartmann, H Rüeger, A Stricker-Krongrad, ... The Journal of clinical investigation 102 (12), 2136-2145, 1998 | 275 | 1998 |
| Inhibition of food intake by neuropeptide Y Y5 receptor antisense oligodeoxynucleotides AO Schaffhauser, A Stricker-Krongrad, L Brunner, F Cumin, C Gerald, ... Diabetes 46 (11), 1792-1798, 1997 | 233 | 1997 |
| Modeling promiscuity based on in vitro safety pharmacology profiling data K Azzaoui, J Hamon, B Faller, S Whitebread, E Jacoby, A Bender, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 874-880, 2007 | 208 | 2007 |
| Mapping adverse drug reactions in chemical space J Scheiber, JL Jenkins, SCK Sukuru, A Bender, D Mikhailov, M Milik, ... Journal of medicinal chemistry 52 (9), 3103-3107, 2009 | 200 | 2009 |
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| Angiotensin II AT2 receptors do not interact with guanine nucleotide binding proteins SP Bottari, V Taylor, IN King, Y Bogdal, S Whitebread, M de Gasparo European Journal of Pharmacology: Molecular Pharmacology 207 (2), 157-163, 1991 | 188 | 1991 |
| Ghrelin acts on leptin‐responsive neurones in the rat arcuate nucleus M Traebert, T Riediger, S Whitebread, E Scharrer, HA Schmid Journal of neuroendocrinology 14 (7), 580-586, 2002 | 162 | 2002 |
| Valsartan, a potent, orally active angiotensin II antagonist developed from the structurally new amino acid series P Bühlmayer, P Furet, L Criscione, M de Gasparo, S Whitebread, ... Bioorganic & Medicinal Chemistry Letters 4 (1), 29-34, 1994 | 149 | 1994 |
| Biochemical characterization of two angiotensin II receptor subtypes in the rat M de Gasparo, S Whitebread, M Mele, AS Motani, PJ Whitcombe, ... Journal of cardiovascular pharmacology 16, S31-S35, 1990 | 141 | 1990 |
| Binding of valsartan to mammalian angiotensin AT1 receptors M de Gasparo, S Whitebread Regulatory peptides 59 (3), 303-311, 1995 | 140 | 1995 |
| Radioiodinated cgp 42111A: a novel high affinity and highly selective ligand for the characterization of angiotensin AT2 receptors SE Whitebread, V Taylor, SP Bottari, B Kamber, M de Gasparo Biochemical and biophysical research communications 181 (3), 1365-1371, 1991 | 117 | 1991 |
| Antialdosterones: incidence and prevention of sexual side effects M De Gasparo, SE Whitebread, G Preiswerk, X Jeunemaitre, P Corvol, ... Journal of steroid biochemistry 32 (1), 223-227, 1989 | 109 | 1989 |
