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Niamh M C Connolly
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Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
NMC Connolly, P Theurey, V Adam-Vizi, NG Bazan, P Bernardi, ...
Cell Death & Differentiation, 1, 2017
1472017
Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus
R Raoof, EM Jimenez-Mateos, S Bauer, B Tackenberg, F Rosenow, ...
Scientific reports 7 (1), 3328, 2017
1142017
Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy
R Raoof, S Bauer, H El Naggar, NMC Connolly, GP Brennan, E Brindley, ...
EBioMedicine 38, 127-141, 2018
982018
Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate
D Davila, NMC Connolly, H Bonner, P Weisová, H Dussmann, ...
Cell Death & Differentiation 19 (10), 1677-1688, 2012
812012
Single-cell imaging of bioenergetic responses to neuronal excitotoxicity and oxygen and glucose deprivation
NMC Connolly, H Düssmann, U Anilkumar, HJ Huber, JHM Prehn
Journal of Neuroscience 34 (31), 10192-10205, 2014
672014
miRNAmeConverter: an R/bioconductor package for translating mature miRNA names to different miRBase versions
SJ Haunsberger, NMC Connolly, JHM Prehn
Bioinformatics 33 (4), 592-593, 2017
552017
Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer's disease neurons
P Theurey, NMC Connolly, I Fortunati, E Basso, S Lauwen, C Ferrante, ...
Aging cell 18 (3), e12924, 2019
542019
A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy
MT Venø, CR Reschke, G Morris, NMC Connolly, J Su, Y Yan, T Engel, ...
Proceedings of the National Academy of Sciences 117 (27), 15977-15988, 2020
512020
Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy
GP Brennan, S Bauer, T Engel, EM Jimenez-Mateos, F Del Gallo, ...
Neurobiology of Disease 144, 105048, 2020
452020
The metabolic response to excitotoxicity–lessons from single-cell imaging
NMC Connolly, JHM Prehn
Journal of bioenergetics and biomembranes 47 (1-2), 75-88, 2015
372015
Mechanisms and mathematical modeling of ROS production by the mitochondrial electron transport chain
S Chenna, WJH Koopman, JHM Prehn, NMC Connolly
American Journal of Physiology-Cell Physiology 323 (1), C69-C83, 2022
322022
Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
L Naia, CM Pinho, G Dentoni, J Liu, NS Leal, DMS Ferreira, B Schreiner, ...
BMC biology 19, 1-21, 2021
292021
Altered biogenesis and microRNA content of hippocampal exosomes following experimental status epilepticus
A Batool, TDM Hill, NT Nguyen, E Langa, M Diviney, C Mooney, ...
Frontiers in neuroscience 13, 1404, 2020
242020
Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy
CR Reschke, LFA Silva, VR Vangoor, M Rosso, B David, BL Cavanagh, ...
Molecular Therapy 29 (6), 2041-2052, 2021
232021
AMPK Preferentially Depresses Retrograde Transport of Axonal Mitochondria during Localized Nutrient Deprivation
O Watters, NMC Connolly, HG König, H Düssmann, JHM Prehn
Journal of Neuroscience 40 (25), 4798-4812, 2020
222020
Electrical stimulation of the ventral hippocampal commissure delays experimental epilepsy and is associated with altered microRNA expression
LS Costard, V Neubert, MT Venø, J Su, J Kjems, NMC Connolly, ...
Brain Stimulation 12 (6), 1390-1401, 2019
182019
Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform
U Anilkumar, P Weisova, J Schmid, T Bernas, HJ Huber, H Düssmann, ...
PloS one 12 (11), e0188343, 2017
152017
Computational Analysis of AMPK-Mediated Neuroprotection Suggests Acute Excitotoxic Bioenergetics and Glucose Dynamics Are Regulated by a Minimal Set of Critical Reactions
NMC Connolly, B D¢Orsi, N Monsefi, HJ Huber, JHM Prehn
PloS one 11 (2), e0148326, 2016
142016
MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control
M Heiland, NMC Connolly, O Mamad, NT Nguyen, JC Kesavan, E Langa, ...
Proceedings of the National Academy of Sciences 120 (30), e2216658120, 2023
112023
Targeting the apoptosis pathway to treat tumours of the paediatric nervous system
MC Fitzgerald, PJ O¢Halloran, NMC Connolly, BM Murphy
Cell Death & Disease 13 (5), 460, 2022
112022
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Articles 1–20