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Robert Ragotte
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Robust deep learning–based protein sequence design using ProteinMPNN
J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ...
Science 378 (6615), 49-56, 2022
5462022
De novo design of protein structure and function with RFdiffusion
JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ...
Nature 620 (7976), 1089-1100, 2023
479*2023
Scaffolding protein functional sites using deep learning
J Wang, S Lisanza, D Juergens, D Tischer, JL Watson, KM Castro, ...
Science 377 (6604), 387-394, 2022
2412022
Hallucinating symmetric protein assemblies
BIM Wicky, LF Milles, A Courbet, RJ Ragotte, J Dauparas, E Kinfu, S Tipps, ...
Science 378 (6615), 56-61, 2022
1232022
JAK1 gain-of-function causes an autosomal dominant immune dysregulatory and hypereosinophilic syndrome
KL Del Bel, RJ Ragotte, A Saferali, S Lee, SM Vercauteren, SA Mostafavi, ...
Journal of Allergy and Clinical Immunology 139 (6), 2016-2020. e5, 2017
1202017
The RH5-CyRPA-Ripr complex as a malaria vaccine target
RJ Ragotte, MK Higgins, SJ Draper
Trends in parasitology 36 (6), 545-559, 2020
552020
The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus
RJ Ragotte, A Dhanrajani, J Pleydell-Pearce, KL Del Bel, ...
Clinical immunology 175, 143-146, 2017
492017
Human Basigin (CD147) Does Not Directly Interact with SARS-CoV-2 Spike Glycoprotein
RJ Ragotte, D Pulido, FR Donnellan, ML Hill, G Gorini, H Davies, J Brun, ...
mSphere 6 (4), e0064721, 2021
40*2021
Heterotypic interactions drive antibody synergy against a malaria vaccine candidate
RJ Ragotte, D Pulido, AM Lias, D Quinkert, DGW Alanine, A Jamwal, ...
Nature communications 13 (1), 933, 2022
242022
A systematic review and meta-analysis of patient data from the west Africa (2013–16) Ebola virus disease epidemic
AM Rojek, A Salam, RJ Ragotte, E Liddiard, A Elhussain, A Carlqvist, ...
Clinical Microbiology and Infection 25 (11), 1307-1314, 2019
162019
Human JAK1 gain of function causes dysregulated myelopoeisis and severe allergic inflammation
CM Biggs, A Cordeiro-Santanach, SV Prykhozhij, AP Deveau, Y Lin, ...
JCI insight 7 (24), 2022
62022
The PfRCR complex bridges malaria parasite and erythrocyte during invasion
B Farrell, N Alam, MN Hart, A Jamwal, RJ Ragotte, H Walters-Morgan, ...
Nature 625 (7995), 578-584, 2024
52024
Structure of the PfRCR complex which bridges the malaria parasite and erythrocyte during invasion
B Farrell, N Alam, MN Hart, A Jamwal, RJ Ragotte, H Walters-Morgan, ...
bioRxiv, 2023.01. 30.526221, 2023
32023
The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites
GE Weiss, RJ Ragotte, D Quinkert, AM Lias, MG Dans, C Boulet, O Looker, ...
PLoS Pathogens 19 (9), e1011182, 2023
22023
Atomically accurate de novo design of single-domain antibodies
NR Bennett, JL Watson, RJ Ragotte, AJ Borst, DL See, C Weidle, ...
bioRxiv, 2024.03. 14.585103, 2024
12024
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex
BG Williams, LDW King, D Pulido, D Quinker, AM Lias, SE Silk, ...
bioRxiv, 2024.02. 08.579322, 2024
12024
Idiopathic splenomegaly in childhood and the spectrum of RAS-associated lymphoproliferative disease: a case report
G Blanchard-Rohner, RJ Ragotte, AK Junker, M Sharma, KL Del Bel, ...
BMC pediatrics 21, 1-4, 2021
12021
De Novo Designed Homo-Oligomeric Protein Assemblies
D Baker, B Wicky, L Milles, A Courbet, R Ragotte, E Kinfu, S Tipps, ...
US Patent App. 18/348,528, 2024
2024
Scaffolding protein functional sites using deep learning
D Baker, J Wang, R Ragotte, L Milles, JL Watson, D Juergens, S Lisanza, ...
US Patent App. 18/339,519, 2023
2023
Track: Machine Learning in Protein Science De Novo Design of Viral Epitope Mimetics with Non-Regular Structural Features
K Castro, J Wang, L Milles, J Watson, R Ragotte, A Vorobieva, D Baker, ...
Protein Science 32, 2023
2023
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