Joseph Mougous
Joseph Mougous
University of Washington, Howard Hughes Medical Institute
Verified email at - Homepage
Cited by
Cited by
A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus
JD Mougous, ME Cuff, S Raunser, A Shen, M Zhou, CA Gifford, ...
Science 312 (5779), 1526-1530, 2006
A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria
RD Hood, P Singh, FS Hsu, T Güvener, MA Carl, RRS Trinidad, ...
Cell host & microbe 7 (1), 25-37, 2010
Type VI secretion delivers bacteriolytic effectors to target cells
AB Russell, RD Hood, NK Bui, M LeRoux, W Vollmer, JD Mougous
Nature 475 (7356), 343-347, 2011
Type VI secretion system effectors: poisons with a purpose
AB Russell, SB Peterson, JD Mougous
Nature reviews microbiology 12 (2), 137-148, 2014
A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing
BY Mok, MH de Moraes, J Zeng, DE Bosch, AV Kotrys, A Raguram, ...
Nature 583 (7817), 631-637, 2020
Structure and regulation of the type VI secretion system
JM Silverman, YR Brunet, E Cascales, JD Mougous
Annual review of microbiology 66, 453-472, 2012
Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions
S Schwarz, TE West, F Boyer, WC Chiang, MA Carl, RD Hood, L Rohmer, ...
PLoS pathogens 6 (8), e1001068, 2010
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors
AB Russell, M LeRoux, K Hathazi, DM Agnello, T Ishikawa, PA Wiggins, ...
Nature 496 (7446), 508, 2013
Threonine phosphorylation post-translationally regulates protein secretion in Pseudomonas aeruginosa
JD Mougous, CA Gifford, TL Ramsdell, JJ Mekalanos
Nature cell biology 9 (7), 797-803, 2007
A type VI secretion-related pathway in Bacteroidetes mediates interbacterial antagonism
AB Russell, AG Wexler, BN Harding, JC Whitney, AJ Bohn, YA Goo, ...
Cell host & microbe 16 (2), 227-236, 2014
In vitro self-assembly of tailorable nanotubes from a simple protein building block
ER Ballister, AH Lai, RN Zuckermann, Y Cheng, JD Mougous
Proceedings of the National Academy of Sciences 105 (10), 3733-3738, 2008
A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach
AB Russell, P Singh, M Brittnacher, NK Bui, RD Hood, MA Carl, ...
Cell host & microbe 11 (5), 538-549, 2012
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence
SE Converse, JD Mougous, MD Leavell, JA Leary, CR Bertozzi, JS Cox
Proceedings of the National Academy of Sciences 100 (10), 6121-6126, 2003
Haemolysin coregulated protein is an exported receptor and chaperone of type VI secretion substrates
JM Silverman, DM Agnello, H Zheng, BT Andrews, M Li, CE Catalano, ...
Molecular cell 51 (5), 584-593, 2013
What is type VI secretion doing in all those bugs?
S Schwarz, RD Hood, JD Mougous
Trends in microbiology 18 (12), 531-537, 2010
Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling
M Jain, CJ Petzold, MW Schelle, MD Leavell, JD Mougous, CR Bertozzi, ...
Proceedings of the National Academy of Sciences 104 (12), 5133-5138, 2007
An interbacterial NAD (P)+ glycohydrolase toxin requires elongation factor Tu for delivery to target cells
JC Whitney, D Quentin, S Sawai, M LeRoux, BN Harding, HE Ledvina, ...
Cell 163 (3), 607-619, 2015
Human symbionts inject and neutralize antibacterial toxins to persist in the gut
AG Wexler, Y Bao, JC Whitney, LM Bobay, JB Xavier, WB Schofield, ...
Proceedings of the National Academy of Sciences 113 (13), 3639-3644, 2016
Genetically distinct pathways guide effector export through the type VI secretion system
JC Whitney, CM Beck, YA Goo, AB Russell, BN Harding, JA De Leon, ...
Molecular microbiology 92 (3), 529-542, 2014
VgrG-5 is a Burkholderia type VI secretion system-exported protein required for multinucleated giant cell formation and virulence
S Schwarz, P Singh, JD Robertson, M LeRoux, SJ Skerrett, DR Goodlett, ...
Infection and immunity 82 (4), 1445-1452, 2014
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