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| Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation P Zhang, D Wang, Y Zhao, S Ren, K Gao, Z Ye, S Wang, CW Pan, Y Zhu, ... Nature medicine 23 (9), 1055-1062, 2017 | 254 | 2017 |
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| Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer Y He, S Peng, J Wang, H Chen, X Cong, A Chen, M Hu, M Qin, H Wu, ... Nature communications 7 (1), 13122, 2016 | 80 | 2016 |
| Destruction of DNA‐binding proteins by programmable oligonucleotide PROTAC (O'PROTAC): effective targeting of LEF1 and ERG J Shao, Y Yan, D Ding, D Wang, Y He, Y Pan, W Yan, A Kharbanda, H Li, ... Advanced Science 8 (20), 2102555, 2021 | 70 | 2021 |
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| TMPRSS2-ERG Controls Luminal Epithelial Lineage and Antiandrogen Sensitivity in PTEN and TP53-Mutated Prostate Cancer AM Blee, Y He, Y Yang, Z Ye, Y Yan, Y Pan, T Ma, J Dugdale, E Kuehn, ... Clinical Cancer Research 24 (18), 4551-4565, 2018 | 60 | 2018 |
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| A noncanonical AR addiction drives enzalutamide resistance in prostate cancer Y He, T Wei, Z Ye, JJ Orme, D Lin, H Sheng, L Fazli, R Jeffrey Karnes, ... Nature communications 12 (1), 1521, 2021 | 54 | 2021 |
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| Targeting pyruvate carboxylase by a small molecule suppresses breast cancer progression Q Lin, Y He, X Wang, Y Zhang, M Hu, W Guo, Y He, T Zhang, L Lai, Z Sun, ... Advanced Science 7 (9), 1903483, 2020 | 42 | 2020 |
| Aberrant activation of super enhancer and choline metabolism drive antiandrogen therapy resistance in prostate cancer S Wen, Y He, L Wang, J Zhang, C Quan, Y Niu, H Huang Oncogene 39 (42), 6556-6571, 2020 | 37 | 2020 |
| A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer J Wang, Y Xing, Y Wang, Y He, L Wang, S Peng, L Yang, J Xie, X Li, ... Journal of Experimental & Clinical Cancer Research 38, 1-14, 2019 | 33 | 2019 |
| Mutated SPOP E3 ligase promotes 17βHSD4 protein degradation to drive androgenesis and prostate cancer progression L Shi, Y Yan, Y He, B Yan, Y Pan, JJ Orme, J Zhang, W Xu, J Pang, ... Cancer research 81 (13), 3593-3606, 2021 | 19 | 2021 |
| SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition J Ma, Q Shi, G Cui, H Sheng, MV Botuyan, Y Zhou, Y Yan, Y He, L Wang, ... Nature communications 12 (1), 5779, 2021 | 16 | 2021 |
